diff --git a/Microsoft.Azure.Cosmos/src/DocumentClient.cs b/Microsoft.Azure.Cosmos/src/DocumentClient.cs
index 1f86e7cc78..b52496cf8a 100644
--- a/Microsoft.Azure.Cosmos/src/DocumentClient.cs
+++ b/Microsoft.Azure.Cosmos/src/DocumentClient.cs
@@ -1030,7 +1030,7 @@ internal virtual void Initialize(Uri serviceEndpoint,
             this.ConnectionPolicy = connectionPolicy ?? ConnectionPolicy.Default;
 
 #if !NETSTANDARD16
-            ServicePoint servicePoint = ServicePointManager.FindServicePoint(this.ServiceEndpoint);
+            ServicePointAccessor servicePoint = ServicePointAccessor.FindServicePoint(this.ServiceEndpoint);
             servicePoint.ConnectionLimit = this.ConnectionPolicy.MaxConnectionLimit;
 #endif
 
diff --git a/Microsoft.Azure.Cosmos/src/Routing/LocationCache.cs b/Microsoft.Azure.Cosmos/src/Routing/LocationCache.cs
index 561074321b..9b70757e89 100644
--- a/Microsoft.Azure.Cosmos/src/Routing/LocationCache.cs
+++ b/Microsoft.Azure.Cosmos/src/Routing/LocationCache.cs
@@ -565,7 +565,7 @@ private bool CanUseMultipleWriteLocations()
         private void SetServicePointConnectionLimit(Uri endpoint)
         {
 #if !NETSTANDARD16
-            ServicePoint servicePoint = ServicePointManager.FindServicePoint(endpoint);
+            ServicePointAccessor servicePoint = ServicePointAccessor.FindServicePoint(endpoint);
             servicePoint.ConnectionLimit = this.connectionLimit;
 #endif
         }
diff --git a/Microsoft.Azure.Cosmos/src/Util/ServicePointAccessor.cs b/Microsoft.Azure.Cosmos/src/Util/ServicePointAccessor.cs
new file mode 100644
index 0000000000..fc642ff054
--- /dev/null
+++ b/Microsoft.Azure.Cosmos/src/Util/ServicePointAccessor.cs
@@ -0,0 +1,57 @@
+//------------------------------------------------------------
+// Copyright (c) Microsoft Corporation.  All rights reserved.
+//------------------------------------------------------------
+
+namespace Microsoft.Azure.Cosmos
+{
+    using System;
+    using System.Net;
+    using System.Runtime.InteropServices;
+    using Microsoft.Azure.Cosmos.Core.Trace;
+
+    /// <summary>
+    /// While ServicePoint is a NETStandard 2.0 API, not all runtimes support the operations and some Framework implementations might not support it.
+    /// </summary>
+    internal class ServicePointAccessor
+    {
+        // WebAssembly detection
+        private static bool IsBrowser = RuntimeInformation.IsOSPlatform(OSPlatform.Create("BROWSER")) || RuntimeInformation.IsOSPlatform(OSPlatform.Create("WEBASSEMBLY"));
+
+        private readonly ServicePoint servicePoint;
+
+        private ServicePointAccessor(ServicePoint servicePoint)
+        {
+            this.servicePoint = servicePoint ?? throw new ArgumentNullException(nameof(servicePoint));
+        }
+
+        internal static ServicePointAccessor FindServicePoint(Uri endpoint)
+        {
+            return new ServicePointAccessor(ServicePointManager.FindServicePoint(endpoint));
+        }
+
+        public int ConnectionLimit
+        {
+            get => this.servicePoint.ConnectionLimit;
+            set => this.TrySetConnectionLimit(value);
+        }
+
+        private void TrySetConnectionLimit(int connectionLimit)
+        {
+            if (ServicePointAccessor.IsBrowser)
+            {
+                // Workaround for WebAssembly.
+                // WebAssembly currently throws a SynchronizationLockException and not a PlatformNotSupportedException.
+                return; 
+            }
+
+            try
+            {
+                this.servicePoint.ConnectionLimit = connectionLimit;
+            }
+            catch (PlatformNotSupportedException)
+            {
+                DefaultTrace.TraceWarning("ServicePoint.set_ConnectionLimit - Platform does not support feature.");
+            }
+        }
+    }
+}
diff --git a/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.Tests/ServicePointAccessorTests.cs b/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.Tests/ServicePointAccessorTests.cs
new file mode 100644
index 0000000000..f5258f2b0a
--- /dev/null
+++ b/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.Tests/ServicePointAccessorTests.cs
@@ -0,0 +1,27 @@
+//------------------------------------------------------------
+// Copyright (c) Microsoft Corporation.  All rights reserved.
+//------------------------------------------------------------
+
+namespace Microsoft.Azure.Cosmos.Tests
+{
+    using System;
+    using System.Net;
+    using Microsoft.VisualStudio.TestTools.UnitTesting;
+
+    [TestClass]
+    public class ServicePointAccessorTests
+    {
+        private static Uri uri = new Uri("https://localhost");
+
+        [TestMethod]
+        public void ServicePointAccessor_SetConnectionLimit()
+        {
+            int limit = 10;
+            ServicePointAccessor accessor = ServicePointAccessor.FindServicePoint(ServicePointAccessorTests.uri);
+            Assert.IsNotNull(accessor);
+            accessor.ConnectionLimit = limit;
+            ServicePoint servicePoint = ServicePointManager.FindServicePoint(ServicePointAccessorTests.uri);
+            Assert.AreEqual(limit, servicePoint.ConnectionLimit);
+        }
+    }
+}