diff --git a/src/util.h b/src/util.h
index fd6cc643e..dac86bd77 100644
--- a/src/util.h
+++ b/src/util.h
@@ -173,31 +173,6 @@ static SECP256K1_INLINE void *checked_realloc(const secp256k1_callback* cb, void
 # define SECP256K1_GNUC_EXT
 #endif
 
-/* If SECP256K1_{LITTLE,BIG}_ENDIAN is not explicitly provided, infer from various other system macros. */
-#if !defined(SECP256K1_LITTLE_ENDIAN) && !defined(SECP256K1_BIG_ENDIAN)
-/* Inspired by https://github.com/rofl0r/endianness.h/blob/9853923246b065a3b52d2c43835f3819a62c7199/endianness.h#L52L73 */
-# if (defined(__BYTE_ORDER__) && defined(__ORDER_LITTLE_ENDIAN__) && __BYTE_ORDER__ == __ORDER_LITTLE_ENDIAN__) || \
-     defined(_X86_) || defined(__x86_64__) || defined(__i386__) || \
-     defined(__i486__) || defined(__i586__) || defined(__i686__) || \
-     defined(__MIPSEL) || defined(_MIPSEL) || defined(MIPSEL) || \
-     defined(__ARMEL__) || defined(__AARCH64EL__) || \
-     (defined(__LITTLE_ENDIAN__) && __LITTLE_ENDIAN__ == 1) || \
-     (defined(_LITTLE_ENDIAN) && _LITTLE_ENDIAN == 1) || \
-     defined(_M_IX86) || defined(_M_AMD64) || defined(_M_ARM) /* MSVC */
-#  define SECP256K1_LITTLE_ENDIAN
-# endif
-# if (defined(__BYTE_ORDER__) && defined(__ORDER_BIG_ENDIAN__) && __BYTE_ORDER__ == __ORDER_BIG_ENDIAN__) || \
-     defined(__MIPSEB) || defined(_MIPSEB) || defined(MIPSEB) || \
-     defined(__MICROBLAZEEB__) || defined(__ARMEB__) || defined(__AARCH64EB__) || \
-     (defined(__BIG_ENDIAN__) && __BIG_ENDIAN__ == 1) || \
-     (defined(_BIG_ENDIAN) && _BIG_ENDIAN == 1)
-#  define SECP256K1_BIG_ENDIAN
-# endif
-#endif
-#if defined(SECP256K1_LITTLE_ENDIAN) == defined(SECP256K1_BIG_ENDIAN)
-# error Please make sure that either SECP256K1_LITTLE_ENDIAN or SECP256K1_BIG_ENDIAN is set, see src/util.h.
-#endif
-
 /* Zero memory if flag == 1. Flag must be 0 or 1. Constant time. */
 static SECP256K1_INLINE void secp256k1_memczero(void *s, size_t len, int flag) {
     unsigned char *p = (unsigned char *)s;