diff --git a/packages/core/src/domain/configuration.spec.ts b/packages/core/src/domain/configuration.spec.ts
index 216c6d9a03..3f2983431a 100644
--- a/packages/core/src/domain/configuration.spec.ts
+++ b/packages/core/src/domain/configuration.spec.ts
@@ -132,6 +132,16 @@ describe('configuration', () => {
       expect(configuration.isIntakeUrl('https://trace.browser-intake-datadoghq.com/v1/input/xxx')).toBe(true)
     })
 
+    it('should handle sites with subdomains', () => {
+      const configuration = buildConfiguration(
+        { clientToken, site: 'us3.datadoghq.com', useAlternateIntakeDomains: true },
+        usEnv
+      )
+      expect(configuration.isIntakeUrl('https://rum.browser-intake-us3-datadoghq.com/v1/input/xxx')).toBe(true)
+      expect(configuration.isIntakeUrl('https://logs.browser-intake-us3-datadoghq.com/v1/input/xxx')).toBe(true)
+      expect(configuration.isIntakeUrl('https://trace.browser-intake-us3-datadoghq.com/v1/input/xxx')).toBe(true)
+    })
+
     it('should detect proxy intake request', () => {
       let configuration = buildConfiguration({ clientToken, proxyHost: 'www.proxy.com' }, usEnv)
       expect(configuration.isIntakeUrl('https://www.proxy.com/v1/input/xxx')).toBe(true)
diff --git a/packages/core/src/domain/configuration.ts b/packages/core/src/domain/configuration.ts
index f1b41c51fc..8fa7bead08 100644
--- a/packages/core/src/domain/configuration.ts
+++ b/packages/core/src/domain/configuration.ts
@@ -250,7 +250,9 @@ function getEndpoint(
 function getHost(intakeType: IntakeType, endpointType: EndpointType, site: string) {
   const middleDomain = INTAKE_MIDDLE_DOMAINS[intakeType]
   const endpoint = ENDPOINTS[intakeType][endpointType]
-  return `${endpoint}${middleDomain}${site}`
+  const domainParts = site.split('.')
+  const ext = domainParts.pop()
+  return `${endpoint}${middleDomain}${domainParts.join('-')}.${ext}`
 }
 
 function getIntakeUrls(intakeType: IntakeType, conf: TransportConfiguration, withReplica: boolean) {