diff --git a/tracer/build/_build/docker/smoke.dotnet-tool.dockerfile b/tracer/build/_build/docker/smoke.dotnet-tool.dockerfile
index 37c5d0255928..58c422f69173 100644
--- a/tracer/build/_build/docker/smoke.dotnet-tool.dockerfile
+++ b/tracer/build/_build/docker/smoke.dotnet-tool.dockerfile
@@ -32,6 +32,9 @@ ENV DD_TRACE_DEBUG=1
 ENV ASPNETCORE_URLS=http://localhost:5000
 ENV DD_PROFILING_LOG_DIR=/var/log/datadog/dotnet
 
+# see https://github.com/dotnet/runtime/issues/77973
+ENV COMPlus_TieredCompilation=0
+
 # Copy the app across
 COPY --from=builder /src/publish /app/.
 
diff --git a/tracer/build/_build/docker/smoke.dotnet-tool.nuget.dockerfile b/tracer/build/_build/docker/smoke.dotnet-tool.nuget.dockerfile
index bfb6b78b5cd5..631c6bb5b1d6 100644
--- a/tracer/build/_build/docker/smoke.dotnet-tool.nuget.dockerfile
+++ b/tracer/build/_build/docker/smoke.dotnet-tool.nuget.dockerfile
@@ -32,6 +32,9 @@ ENV DD_TRACE_DEBUG=1
 ENV ASPNETCORE_URLS=http://localhost:5000
 ENV DD_PROFILING_LOG_DIR=/var/log/datadog/dotnet
 
+# see https://github.com/dotnet/runtime/issues/77973
+ENV COMPlus_TieredCompilation=0
+
 # Copy the app across
 COPY --from=builder /src/publish /app/.
 
diff --git a/tracer/build/_build/docker/smoke.windows.dockerfile b/tracer/build/_build/docker/smoke.windows.dockerfile
index d4f73c8a83c5..7ba449fe8a8d 100644
--- a/tracer/build/_build/docker/smoke.windows.dockerfile
+++ b/tracer/build/_build/docker/smoke.windows.dockerfile
@@ -43,6 +43,9 @@ ENV DD_PROFILING_ENABLED=1 \
     DD_PROFILING_LOG_DIR="C:\logs" \
     ASPNETCORE_URLS=http://localhost:5000
 
+# see https://github.com/dotnet/runtime/issues/77973
+ENV COMPlus_TieredCompilation=0
+
 # Copy the app across
 COPY --from=builder /src/publish /app/.
 
diff --git a/tracer/build/_build/docker/smoke.windows.dotnet-tool.dockerfile b/tracer/build/_build/docker/smoke.windows.dotnet-tool.dockerfile
index 3a76ff82444f..7a2674291ce2 100644
--- a/tracer/build/_build/docker/smoke.windows.dotnet-tool.dockerfile
+++ b/tracer/build/_build/docker/smoke.windows.dotnet-tool.dockerfile
@@ -43,6 +43,9 @@ ENV DD_PROFILING_ENABLED=1 \
     DD_PROFILING_LOG_DIR="C:\logs" \
     ASPNETCORE_URLS=http://localhost:5000
 
+# see https://github.com/dotnet/runtime/issues/77973
+ENV COMPlus_TieredCompilation=0
+
 # Copy the app across
 COPY --from=builder /src/publish /app/.
 
diff --git a/tracer/build/_build/docker/smoke.windows.nuget.dockerfile b/tracer/build/_build/docker/smoke.windows.nuget.dockerfile
index 1beff6f20bef..74a3b6d5c107 100644
--- a/tracer/build/_build/docker/smoke.windows.nuget.dockerfile
+++ b/tracer/build/_build/docker/smoke.windows.nuget.dockerfile
@@ -46,6 +46,9 @@ ENV CORECLR_ENABLE_PROFILING=1 \
     DD_PROFILING_ENABLED=1 \
     ASPNETCORE_URLS=http://localhost:5000
 
+# see https://github.com/dotnet/runtime/issues/77973
+ENV COMPlus_TieredCompilation=0
+
 # Copy the app across
 COPY --from=builder /src/publish /app/.
 
diff --git a/tracer/build/_build/docker/smoke.windows.tracer-home.dockerfile b/tracer/build/_build/docker/smoke.windows.tracer-home.dockerfile
index 113a0472208b..7f8e02171112 100644
--- a/tracer/build/_build/docker/smoke.windows.tracer-home.dockerfile
+++ b/tracer/build/_build/docker/smoke.windows.tracer-home.dockerfile
@@ -50,6 +50,9 @@ ENV DD_PROFILING_ENABLED=1 \
     DD_PROFILING_LOG_DIR="C:\logs" \
     ASPNETCORE_URLS=http://localhost:5000
 
+# see https://github.com/dotnet/runtime/issues/77973
+ENV COMPlus_TieredCompilation=0
+
 # Copy the app across
 COPY --from=builder /src/publish /app/.
 
diff --git a/tracer/test/Datadog.Trace.TestHelpers/EnvironmentHelper.cs b/tracer/test/Datadog.Trace.TestHelpers/EnvironmentHelper.cs
index 1b57f96a4cb2..2e3a6906a244 100644
--- a/tracer/test/Datadog.Trace.TestHelpers/EnvironmentHelper.cs
+++ b/tracer/test/Datadog.Trace.TestHelpers/EnvironmentHelper.cs
@@ -189,6 +189,7 @@ public void SetEnvironmentVariables(
         {
             string profilerEnabled = AutomaticInstrumentationEnabled ? "1" : "0";
             environmentVariables["DD_DOTNET_TRACER_HOME"] = MonitoringHome;
+            environmentVariables["COMPlus_TieredCompilation"] = "0";
 
             // Everything should be using the native loader now
             var nativeLoaderPath = GetNativeLoaderPath();