diff --git a/.github/workflows/project.yml b/.github/workflows/project.yml
index 38c43297947..92a97c56457 100644
--- a/.github/workflows/project.yml
+++ b/.github/workflows/project.yml
@@ -18,7 +18,7 @@ jobs:
       # setting fail-fast to false in an attempt to prevent this from happening
       fail-fast: false
       matrix:
-        version: [18, 20, latest]
+        version: [18, 20, 22, latest]
     runs-on: ubuntu-latest
     steps:
       - uses: actions/checkout@v4
@@ -34,7 +34,7 @@ jobs:
   integration-guardrails:
     strategy:
       matrix:
-        version: [12, 14, 16]
+        version: [12.0.0, 12, 14.0.0, 14, 16.0.0, 16, 18.0.0, 18.1.0, 20.0.0, 22.0.0]
     runs-on: ubuntu-latest
     steps:
       - uses: actions/checkout@v4
diff --git a/init.js b/init.js
index 8b183fc17ab..d9286b0307f 100644
--- a/init.js
+++ b/init.js
@@ -2,7 +2,9 @@
 
 /* eslint-disable no-var */
 
-var NODE_MAJOR = require('./version').NODE_MAJOR
+var nodeVersion = require('./version')
+var NODE_MAJOR = nodeVersion.NODE_MAJOR
+var NODE_MINOR = nodeVersion.NODE_MINOR
 
 // We use several things that are not supported by older versions of Node:
 // - AsyncLocalStorage
@@ -11,7 +13,7 @@ var NODE_MAJOR = require('./version').NODE_MAJOR
 // - Mocha (for testing)
 // and probably others.
 // TODO: Remove all these dependencies so that we can report telemetry.
-if (NODE_MAJOR >= 12) {
+if ((NODE_MAJOR === 12 && NODE_MINOR >= 17) || NODE_MAJOR > 12) {
   var path = require('path')
   var Module = require('module')
   var semver = require('semver')
diff --git a/initialize.mjs b/initialize.mjs
index 777f45cc046..104e253d22d 100644
--- a/initialize.mjs
+++ b/initialize.mjs
@@ -31,11 +31,16 @@ ${result.source}`
   return result
 }
 
+const [NODE_MAJOR, NODE_MINOR] = process.versions.node.split('.').map(x => +x)
+
+const brokenLoaders = NODE_MAJOR === 18 && NODE_MINOR === 0
+
 export async function load (...args) {
-  return insertInit(await origLoad(...args))
+  const loadHook = brokenLoaders ? args[args.length - 1] : origLoad
+  return insertInit(await loadHook(...args))
 }
 
-export const resolve = origResolve
+export const resolve = brokenLoaders ? undefined : origResolve
 
 export const getFormat = origGetFormat
 
diff --git a/integration-tests/init.spec.js b/integration-tests/init.spec.js
index 571179276e1..3c37004f607 100644
--- a/integration-tests/init.spec.js
+++ b/integration-tests/init.spec.js
@@ -20,6 +20,7 @@ const telemetryGood = ['complete', 'injection_forced:false']
 const { engines } = require('../package.json')
 const supportedRange = engines.node
 const currentVersionIsSupported = semver.satisfies(process.versions.node, supportedRange)
+const currentVersionCanLog = semver.satisfies(process.versions.node, '>=12.17.0')
 
 // These are on by default in release tests, so we'll turn them off for
 // more fine-grained control of these variables in these tests.
@@ -83,7 +84,30 @@ function testRuntimeVersionChecks (arg, filename) {
       }
     }
 
-    if (!currentVersionIsSupported) {
+    if (!currentVersionCanLog) {
+      context('when node version is too low for AsyncLocalStorage', () => {
+        useEnv({ NODE_OPTIONS })
+
+        it('should initialize the tracer, if no DD_INJECTION_ENABLED', () =>
+          doTest('false\n'))
+        context('with DD_INJECTION_ENABLED', () => {
+          useEnv({ DD_INJECTION_ENABLED })
+
+          context('without debug', () => {
+            it('should not initialize the tracer', () => doTest('false\n'))
+            it('should not, if DD_INJECT_FORCE', () => doTestForced('false\n'))
+          })
+          context('with debug', () => {
+            useEnv({ DD_TRACE_DEBUG })
+
+            it('should not initialize the tracer', () =>
+              doTest('false\n'))
+            it('should initialize the tracer, if DD_INJECT_FORCE', () =>
+              doTestForced('false\n'))
+          })
+        })
+      })
+    } else if (!currentVersionIsSupported) {
       context('when node version is less than engines field', () => {
         useEnv({ NODE_OPTIONS })
 
@@ -165,17 +189,22 @@ describe('init.js', () => {
   testRuntimeVersionChecks('require', 'init.js')
 })
 
-// ESM is not supportable prior to Node.js 12
-if (semver.satisfies(process.versions.node, '>=12')) {
+// ESM is not supportable prior to Node.js 12.17.0, 14.13.1 on the 14.x line,
+// or on 18.0.0 in particular.
+if (
+  semver.satisfies(process.versions.node, '>=12.17.0') &&
+  semver.satisfies(process.versions.node, '>=14.13.1')
+) {
   describe('initialize.mjs', () => {
     useSandbox()
     stubTracerIfNeeded()
 
     context('as --loader', () => {
-      testInjectionScenarios('loader', 'initialize.mjs', true)
+      testInjectionScenarios('loader', 'initialize.mjs',
+        process.versions.node !== '18.0.0')
       testRuntimeVersionChecks('loader', 'initialize.mjs')
     })
-    if (Number(process.versions.node.split('.')[0]) >= 18) {
+    if (semver.satisfies(process.versions.node, '>=20.6.0')) {
       context('as --import', () => {
         testInjectionScenarios('import', 'initialize.mjs', true)
         testRuntimeVersionChecks('loader', 'initialize.mjs')