diff --git a/cookiecutter.json b/cookiecutter.json
index 4994bb6..54a4e9c 100644
--- a/cookiecutter.json
+++ b/cookiecutter.json
@@ -5,6 +5,7 @@
   "org_domain" : "kitware.com",
   "org_name" : "Kitware, Inc.",
   "app_name" : "{{ cookiecutter.project_name }}",
+  "bundle_identifier" : "{{ cookiecutter.org_domain.split('.') | reverse | join('.') }}.{{ cookiecutter.project_name | lower }}",
   "app_version_major": "0",
   "app_version_minor": "1",
   "app_version_patch": "0",
diff --git a/{{cookiecutter.project_name}}/CMakeLists.txt b/{{cookiecutter.project_name}}/CMakeLists.txt
index fa6e2dd..8ad7aa4 100644
--- a/{{cookiecutter.project_name}}/CMakeLists.txt
+++ b/{{cookiecutter.project_name}}/CMakeLists.txt
@@ -57,6 +57,11 @@ endif()
 include(SlicerInitializeBuildType)
 include(SlicerInitializeReleaseType)
 
+# Set application bundle identifier for macOS
+if(APPLE)
+  set(Slicer_MACOSX_BUNDLE_GUI_IDENTIFIER "{{cookiecutter.bundle_identifier}}")
+endif()
+
 # Installation folder and admin account requirement for Windows
 if(WIN32)
   # Note: To avoid escaping issue, make sure to use forward slash when setting