diff --git a/study/src/org/labkey/study/model/DatasetDomainKind.java b/study/src/org/labkey/study/model/DatasetDomainKind.java
index adf1d0b68a0..0268268770a 100644
--- a/study/src/org/labkey/study/model/DatasetDomainKind.java
+++ b/study/src/org/labkey/study/model/DatasetDomainKind.java
@@ -118,8 +118,8 @@ public abstract class DatasetDomainKind extends AbstractDomainKind<DatasetDomain
             new PropertyStorageSpec(DSROWID, JdbcType.BIGINT, 0, PropertyStorageSpec.Special.PrimaryKeyNonClustered, false, true, null),
             new PropertyStorageSpec(CONTAINER, JdbcType.GUID).setNullable(false),
             new PropertyStorageSpec(PARTICIPANTID, JdbcType.VARCHAR, 32).setNullable(false),
-            new PropertyStorageSpec(LSID, JdbcType.VARCHAR, 200),
-            new PropertyStorageSpec(SEQUENCENUM, JdbcType.DECIMAL),
+            new PropertyStorageSpec(LSID, JdbcType.VARCHAR, 200).setNullable(false),
+            new PropertyStorageSpec(SEQUENCENUM, JdbcType.DECIMAL).setNullable(false),
             new PropertyStorageSpec(SOURCELSID, JdbcType.VARCHAR, 200),
             new PropertyStorageSpec(_KEY, JdbcType.VARCHAR, 200),
             new PropertyStorageSpec(QCSTATE, JdbcType.INTEGER),
@@ -135,9 +135,9 @@ public abstract class DatasetDomainKind extends AbstractDomainKind<DatasetDomain
 
         BASE_PROPERTIES = new HashSet<>(Arrays.asList(
             new PropertyStorageSpec(DSROWID, JdbcType.BIGINT, 0, PropertyStorageSpec.Special.PrimaryKeyNonClustered, false, true, null),
-            new PropertyStorageSpec(PARTICIPANTID, JdbcType.VARCHAR, 32),
-            new PropertyStorageSpec(LSID, JdbcType.VARCHAR, 200),
-            new PropertyStorageSpec(SEQUENCENUM, JdbcType.DECIMAL),
+            new PropertyStorageSpec(PARTICIPANTID, JdbcType.VARCHAR, 32).setNullable(false),
+            new PropertyStorageSpec(LSID, JdbcType.VARCHAR, 200).setNullable(false),
+            new PropertyStorageSpec(SEQUENCENUM, JdbcType.DECIMAL).setNullable(false),
             new PropertyStorageSpec(SOURCELSID, JdbcType.VARCHAR, 200),
             new PropertyStorageSpec(_KEY, JdbcType.VARCHAR, 200),
             new PropertyStorageSpec(QCSTATE, JdbcType.INTEGER),