diff --git a/src/Mapster.Tests/WhenMappingToInterface.cs b/src/Mapster.Tests/WhenMappingToInterface.cs
index 5e6f0358..c1261003 100644
--- a/src/Mapster.Tests/WhenMappingToInterface.cs
+++ b/src/Mapster.Tests/WhenMappingToInterface.cs
@@ -9,6 +9,8 @@ namespace Mapster.Tests
     [TestClass]
     public class WhenMappingToInterface
     {
+
+        #region Tests
         [TestInitialize]
         public void Setup()
         {
@@ -266,6 +268,52 @@ public void MappingToInteraceWithReadonlyProps_AllPropsInitialized()
             );
         }
 
+        /// <summary>
+        /// https://github.com/MapsterMapper/Mapster/issues/723
+        /// </summary>
+        [TestMethod]
+        public void MappingToInteraceWithIgnorePrivateSetProperty()
+        {
+            TypeAdapterConfig<InterfaceSource723, InterfaceDestination723>
+                .NewConfig()
+                .TwoWays()
+                .Ignore(dest => dest.Ignore);
+
+            InterfaceSource723 dataSourse = new Data723() { Inter = "IterDataSourse", Ignore = "IgnoreDataSourse" };
+            InterfaceDestination723 dataDestination = new Data723() { Inter = "IterDataDestination", Ignore = "IgnoreDataDestination" };
+
+            var idestination = dataDestination.Adapt<InterfaceDestination723>();
+            var isourse = dataDestination.Adapt<InterfaceSource723>();
+
+            var result = dataSourse.Adapt(dataDestination);
+
+            idestination.Ignore.ShouldBeNull(); // Not create initializer and param in constructor  
+            idestination.Inter.ShouldBe("IterDataDestination");
+
+            result.Ignore.ShouldBe("IgnoreDataDestination");
+            result.Inter.ShouldBe("IterDataSourse");
+        }
+
+        #endregion Tests
+
+        #region TestClasses
+        public interface InterfaceDestination723 : InterfaceSource723
+        {
+            public string Ignore { get; }
+        }
+
+        public interface InterfaceSource723
+        {
+            public string Inter { get; set; }
+        }
+
+        private class Data723 : InterfaceDestination723
+        {
+            public string Ignore { get; set; }
+
+            public string Inter { get; set; }
+        }
+
         public interface IInheritedDtoWithoutProperties : IInheritedDto
         {
         }
@@ -374,6 +422,6 @@ public class PropertyInitializationTestSource
             public int Property1 { get; set; }
             public int Property2 { get; set; }
         }
-
+        #endregion TestClasses
     }
 }
diff --git a/src/Mapster/Adapters/ReadOnlyInterfaceAdapter.cs b/src/Mapster/Adapters/ReadOnlyInterfaceAdapter.cs
index df4a0f66..160767ca 100644
--- a/src/Mapster/Adapters/ReadOnlyInterfaceAdapter.cs
+++ b/src/Mapster/Adapters/ReadOnlyInterfaceAdapter.cs
@@ -33,7 +33,7 @@ protected override Expression CreateInstantiationExpression(Expression source, E
                 if (arg.GetConstructUsing() != null)
                     return base.CreateInstantiationExpression(source, destination, arg);
 
-                var destType = DynamicTypeGenerator.GetTypeForInterface(arg.DestinationType, arg.Settings.Includes.Count > 0);
+                var destType = DynamicTypeGenerator.GetTypeForInterface(arg.DestinationType, arg.Settings.Includes.Count > 0, arg.Settings.Ignore);
                 if (destType == null)
                     return base.CreateInstantiationExpression(source, destination, arg);
                 var ctor = destType.GetConstructors()[0];
diff --git a/src/Mapster/Utils/DynamicTypeGenerator.cs b/src/Mapster/Utils/DynamicTypeGenerator.cs
index 7e901417..82d693bd 100644
--- a/src/Mapster/Utils/DynamicTypeGenerator.cs
+++ b/src/Mapster/Utils/DynamicTypeGenerator.cs
@@ -22,6 +22,16 @@ internal static class DynamicTypeGenerator
         private static readonly ConcurrentDictionary<Type, Type> _generated = new ConcurrentDictionary<Type, Type>();
         private static int _generatedCounter;
 
+        private static IgnoreDictionary ignoreMembers;
+
+        public static Type? GetTypeForInterface(Type interfaceType, bool ignoreError, IgnoreDictionary ignorMembers)
+        {
+            ignoreMembers = ignorMembers;
+
+            return GetTypeForInterface(interfaceType, ignoreError);
+
+        }
+
         public static Type? GetTypeForInterface(Type interfaceType, bool ignoreError)
         {
             try
@@ -86,13 +96,14 @@ private static Type CreateTypeForInterface(Type interfaceType)
 
             if (hasReadonlyProps)
             {
+                var filterargs = DropIgnorMemebers(args);
                 var ctorBuilder = builder.DefineConstructor(MethodAttributes.Public, 
                     CallingConventions.Standard,
-                    args.Select(it => it.FieldType).ToArray());
+                    filterargs.Select(it => it.FieldType).ToArray());
                 var ctorIl = ctorBuilder.GetILGenerator();
-                for (var i = 0; i < args.Count; i++)
+                for (var i = 0; i < filterargs.Count; i++)
                 {
-                    var arg = args[i];
+                    var arg = filterargs[i];
                     ctorBuilder.DefineParameter(i + 1, ParameterAttributes.None, arg.Name.Substring(1));
                     ctorIl.Emit(OpCodes.Ldarg_0);
                     ctorIl.Emit(OpCodes.Ldarg_S, i + 1);
@@ -175,5 +186,27 @@ private static void CreateMethod(TypeBuilder builder, MethodInfo interfaceMethod
 
             builder.DefineMethodOverride(classMethod, interfaceMethod);
         }
+
+        private static List<FieldBuilder> DropIgnorMemebers(List<FieldBuilder> fields)
+        {
+            var ignorFields = ignoreMembers.Select(x => x.Key).ToArray();
+            List<FieldBuilder> filtered = new List<FieldBuilder>();
+
+            if (ignorFields.Length == 0)
+                return fields;
+
+            foreach (var item in fields)
+            {
+                foreach (var check in ignorFields)
+                {
+                    if (item.Name != $"_{MapsterHelper.CamelCase(check)}")
+                    {
+                        filtered.Add(item);
+                    }
+                }
+            }
+
+            return filtered;
+        }
     }
 }