diff --git a/app/core/RPCMethods/RPCMethodMiddleware.ts b/app/core/RPCMethods/RPCMethodMiddleware.ts
index 0389b84ecb8..5b2329c0436 100644
--- a/app/core/RPCMethods/RPCMethodMiddleware.ts
+++ b/app/core/RPCMethods/RPCMethodMiddleware.ts
@@ -324,13 +324,25 @@ export const getRpcMethodMiddleware = ({
       eth_coinbase: getEthAccounts,
       eth_sendTransaction: async () => {
         checkTabActive();
-        await checkActiveAccountAndChainId({
-          hostname,
-          address: req.params[0].from,
-          chainId: req.params[0].chainId,
-          checkSelectedAddress: isMMSDK || isWalletConnect,
+        return RPCMethods.eth_sendTransaction({
+          next,
+          req,
+          res,
+          validateAccountAndChainId: async ({
+            from,
+            chainId,
+          }: {
+            from?: string;
+            chainId?: number;
+          }) => {
+            await checkActiveAccountAndChainId({
+              hostname,
+              address: from,
+              chainId,
+              checkSelectedAddress: isMMSDK || isWalletConnect,
+            });
+          },
         });
-        next();
       },
       eth_signTransaction: async () => {
         // This is implemented later in our middleware stack – specifically, in
diff --git a/app/core/RPCMethods/eth_sendTransaction.test.ts b/app/core/RPCMethods/eth_sendTransaction.test.ts
new file mode 100644
index 00000000000..01667ca4e73
--- /dev/null
+++ b/app/core/RPCMethods/eth_sendTransaction.test.ts
@@ -0,0 +1,110 @@
+// eslint-disable-next-line import/no-nodejs-modules
+import { inspect } from 'util';
+import type { JsonRpcRequest, PendingJsonRpcResponse } from 'json-rpc-engine';
+import eth_sendTransaction from './eth_sendTransaction';
+
+/**
+ * Construct a `eth_sendTransaction` JSON-RPC request.
+ *
+ * @param params - The request parameters.
+ * @returns The JSON-RPC request.
+ */
+function constructSendTransactionRequest(
+  params: unknown,
+): JsonRpcRequest<unknown> & { method: 'eth_sendTransaction' } {
+  return {
+    jsonrpc: '2.0',
+    id: 1,
+    method: 'eth_sendTransaction',
+    params,
+  };
+}
+
+/**
+ * Construct a pending JSON-RPC response.
+ *
+ * @returns A pending JSON-RPC response.
+ */
+function constructPendingJsonRpcResponse(): PendingJsonRpcResponse<unknown> {
+  return {
+    jsonrpc: '2.0',
+    id: 1,
+  };
+}
+
+describe('eth_sendTransaction', () => {
+  it('invokes next middleware for a valid request', async () => {
+    const nextMock = jest.fn();
+    const minimalValidParams = [{}];
+
+    await eth_sendTransaction({
+      next: nextMock,
+      req: constructSendTransactionRequest(minimalValidParams),
+      res: constructPendingJsonRpcResponse(),
+      validateAccountAndChainId: jest.fn(),
+    });
+
+    expect(nextMock).toHaveBeenCalledTimes(1);
+  });
+
+  const invalidParameters = [null, undefined, '', {}];
+  for (const invalidParameter of invalidParameters) {
+    it(`throws a JSON-RPC invalid parameters error if given "${inspect(
+      invalidParameter,
+    )}"`, async () => {
+      const nextMock = jest.fn();
+
+      await expect(
+        async () =>
+          await eth_sendTransaction({
+            next: nextMock,
+            req: constructSendTransactionRequest(invalidParameter),
+            res: constructPendingJsonRpcResponse(),
+            validateAccountAndChainId: jest.fn(),
+          }),
+      ).rejects.toThrow('Invalid parameters: expected an array');
+      expect(nextMock).not.toHaveBeenCalled();
+    });
+  }
+
+  const invalidTransactionParameters = [null, undefined, '', []];
+  for (const invalidTransactionParameter of invalidTransactionParameters) {
+    it(`throws a JSON-RPC invalid parameters error if given "${inspect(
+      invalidTransactionParameter,
+    )}" transaction parameters`, async () => {
+      const nextMock = jest.fn();
+      const invalidParameter = [invalidTransactionParameter];
+
+      await expect(
+        async () =>
+          await eth_sendTransaction({
+            next: nextMock,
+            req: constructSendTransactionRequest(invalidParameter),
+            res: constructPendingJsonRpcResponse(),
+            validateAccountAndChainId: jest.fn(),
+          }),
+      ).rejects.toThrow(
+        'Invalid parameters: expected the first parameter to be an object',
+      );
+      expect(nextMock).not.toHaveBeenCalled();
+    });
+  }
+
+  it('throws any validation errors', async () => {
+    const nextMock = jest.fn();
+    const minimalValidParams = [{}];
+
+    await expect(
+      async () =>
+        await eth_sendTransaction({
+          next: nextMock,
+          req: constructSendTransactionRequest(minimalValidParams),
+          res: constructPendingJsonRpcResponse(),
+          validateAccountAndChainId: jest.fn().mockImplementation(async () => {
+            throw new Error('test validation error');
+          }),
+        }),
+    ).rejects.toThrow('test validation error');
+    expect(nextMock).not.toHaveBeenCalled();
+  });
+});
diff --git a/app/core/RPCMethods/eth_sendTransaction.ts b/app/core/RPCMethods/eth_sendTransaction.ts
new file mode 100644
index 00000000000..0a4b686e78d
--- /dev/null
+++ b/app/core/RPCMethods/eth_sendTransaction.ts
@@ -0,0 +1,55 @@
+import type {
+  AsyncJsonRpcEngineNextCallback,
+  JsonRpcRequest,
+  PendingJsonRpcResponse,
+} from 'json-rpc-engine';
+import { isObject, hasProperty } from '@metamask/utils';
+import { ethErrors } from 'eth-json-rpc-errors';
+
+/**
+ * Handle a `eth_sendTransaction` request.
+ *
+ * @param args - Named arguments.
+ * @param args.checkActiveAccountAndChainId - A function that validates the account and chain ID
+ * used in the transaction.
+ * @param args.req - The JSON-RPC request.
+ * @param args.res - The JSON-RPC response.
+ */
+async function eth_sendTransaction({
+  next,
+  req,
+  res: _res,
+  validateAccountAndChainId,
+}: {
+  validateAccountAndChainId: (args: {
+    from: string;
+    chainId?: number;
+  }) => Promise<void>;
+  next: AsyncJsonRpcEngineNextCallback;
+  req: JsonRpcRequest<unknown> & { method: 'eth_sendTransaction' };
+  res: PendingJsonRpcResponse<unknown>;
+}) {
+  if (
+    !Array.isArray(req.params) &&
+    !(isObject(req.params) && hasProperty(req.params, 0))
+  ) {
+    throw ethErrors.rpc.invalidParams({
+      message: `Invalid parameters: expected an array`,
+    });
+  }
+  const transactionParameters = req.params[0];
+  if (!isObject(transactionParameters)) {
+    throw ethErrors.rpc.invalidParams({
+      message: `Invalid parameters: expected the first parameter to be an object`,
+    });
+  }
+  await validateAccountAndChainId({
+    from: req.params[0].from,
+    chainId: req.params[0].chainId,
+  });
+
+  // This is handled later in the network middleware
+  next();
+}
+
+export default eth_sendTransaction;
diff --git a/app/core/RPCMethods/index.js b/app/core/RPCMethods/index.js
index 2335997a8b5..3c074804744 100644
--- a/app/core/RPCMethods/index.js
+++ b/app/core/RPCMethods/index.js
@@ -1,7 +1,9 @@
+import eth_sendTransaction from './eth_sendTransaction';
 import wallet_addEthereumChain from './wallet_addEthereumChain.js';
 import wallet_switchEthereumChain from './wallet_switchEthereumChain.js';
 
 const RPCMethods = {
+  eth_sendTransaction,
   wallet_addEthereumChain,
   wallet_switchEthereumChain,
 };
diff --git a/package.json b/package.json
index 9a75e41c347..4a980a87396 100644
--- a/package.json
+++ b/package.json
@@ -152,8 +152,8 @@
     "@metamask/message-manager": "^1.0.1",
     "@metamask/network-controller": "^2.0.0",
     "@metamask/permission-controller": "^1.0.2",
-    "@metamask/preferences-controller": "^2.1.0",
     "@metamask/phishing-controller": "^2.0.0",
+    "@metamask/preferences-controller": "^2.1.0",
     "@metamask/sdk-communication-layer": "^0.1.0",
     "@metamask/swaps-controller": "^6.8.0",
     "@metamask/transaction-controller": "^2.0.0",
@@ -324,6 +324,7 @@
     "@metamask/eslint-config": "^7.0.0",
     "@metamask/eslint-config-typescript": "^7.0.0",
     "@metamask/mobile-provider": "^2.1.0",
+    "@metamask/utils": "^5.0.0",
     "@react-native-community/eslint-config": "^2.0.0",
     "@rpii/wdio-html-reporter": "^7.7.1",
     "@storybook/addon-actions": "^5.3",
diff --git a/yarn.lock b/yarn.lock
index 0527edc66bf..0c6dcfc8b6d 100644
--- a/yarn.lock
+++ b/yarn.lock
@@ -1524,6 +1524,27 @@
   resolved "https://registry.yarnpkg.com/@bcoe/v8-coverage/-/v8-coverage-0.2.3.tgz#75a2e8b51cb758a7553d6804a5932d7aace75c39"
   integrity sha512-0hYQ8SB4Db5zvZB4axdMHGwEaQjkZzFjQiN9LVYvIFB2nSUHW9tYpxWriPrWDASIxiaXax83REcLxuSdnGPZtw==
 
+"@chainsafe/as-sha256@^0.3.1":
+  version "0.3.1"
+  resolved "https://registry.yarnpkg.com/@chainsafe/as-sha256/-/as-sha256-0.3.1.tgz#3639df0e1435cab03f4d9870cc3ac079e57a6fc9"
+  integrity sha512-hldFFYuf49ed7DAakWVXSJODuq3pzJEguD8tQ7h+sGkM18vja+OFoJI9krnGmgzyuZC2ETX0NOIcCTy31v2Mtg==
+
+"@chainsafe/persistent-merkle-tree@^0.4.2":
+  version "0.4.2"
+  resolved "https://registry.yarnpkg.com/@chainsafe/persistent-merkle-tree/-/persistent-merkle-tree-0.4.2.tgz#4c9ee80cc57cd3be7208d98c40014ad38f36f7ff"
+  integrity sha512-lLO3ihKPngXLTus/L7WHKaw9PnNJWizlOF1H9NNzHP6Xvh82vzg9F2bzkXhYIFshMZ2gTCEz8tq6STe7r5NDfQ==
+  dependencies:
+    "@chainsafe/as-sha256" "^0.3.1"
+
+"@chainsafe/ssz@0.9.4":
+  version "0.9.4"
+  resolved "https://registry.yarnpkg.com/@chainsafe/ssz/-/ssz-0.9.4.tgz#696a8db46d6975b600f8309ad3a12f7c0e310497"
+  integrity sha512-77Qtg2N1ayqs4Bg/wvnWfg5Bta7iy7IRh8XqXh7oNMeP2HBbBwx8m6yTpA8p0EHItWPEBkgZd5S5/LSlp3GXuQ==
+  dependencies:
+    "@chainsafe/as-sha256" "^0.3.1"
+    "@chainsafe/persistent-merkle-tree" "^0.4.2"
+    case "^1.6.3"
+
 "@cnakazawa/watch@^1.0.3":
   version "1.0.4"
   resolved "https://registry.yarnpkg.com/@cnakazawa/watch/-/watch-1.0.4.tgz#f864ae85004d0fcab6f50be9141c4da368d1656a"
@@ -1913,11 +1934,24 @@
     crc-32 "^1.2.0"
     ethereumjs-util "^7.1.5"
 
+"@ethereumjs/common@^3.1.1":
+  version "3.1.1"
+  resolved "https://registry.yarnpkg.com/@ethereumjs/common/-/common-3.1.1.tgz#6f754c8933727ad781f63ca3929caab542fe184e"
+  integrity sha512-iEl4gQtcrj2udNhEizs04z7WA15ez1QoXL0XzaCyaNgwRyXezIg1DnfNeZUUpJnkrOF/0rYXyq2UFSLxt1NPQg==
+  dependencies:
+    "@ethereumjs/util" "^8.0.5"
+    crc-32 "^1.2.0"
+
 "@ethereumjs/rlp@^4.0.0-beta.2":
   version "4.0.0"
   resolved "https://registry.yarnpkg.com/@ethereumjs/rlp/-/rlp-4.0.0.tgz#66719891bd727251a7f233f9ca80212d1994f8c8"
   integrity sha512-LM4jS5n33bJN60fM5EC8VeyhUgga6/DjCPBV2vWjnfVtobqtOiNC4SQ1MRFqyBSmJGGdB533JZWewyvlcdJtkQ==
 
+"@ethereumjs/rlp@^4.0.1":
+  version "4.0.1"
+  resolved "https://registry.yarnpkg.com/@ethereumjs/rlp/-/rlp-4.0.1.tgz#626fabfd9081baab3d0a3074b0c7ecaf674aaa41"
+  integrity sha512-tqsQiBQDQdmPWE1xkkBq4rlSW5QZpLOUJ5RJh2/9fug+q9tnUhuZoVLk7s0scUIKTOzEtR72DFBXI4WiZcMpvw==
+
 "@ethereumjs/tx@3.0.0":
   version "3.0.0"
   resolved "https://registry.yarnpkg.com/@ethereumjs/tx/-/tx-3.0.0.tgz#8dfd91ed6e91e63996e37b3ddc340821ebd48c81"
@@ -1942,6 +1976,18 @@
     "@ethereumjs/common" "^2.4.0"
     ethereumjs-util "^7.1.0"
 
+"@ethereumjs/tx@^4.1.1":
+  version "4.1.1"
+  resolved "https://registry.yarnpkg.com/@ethereumjs/tx/-/tx-4.1.1.tgz#d1b5bf2c4fd3618f2f333b66e262848530d4686a"
+  integrity sha512-QDj7nuROfoeyK83RObMA0XCZ+LUDdneNkSCIekO498uEKTY25FxI4Whduc/6j0wdd4IqpQvkq+/7vxSULjGIBQ==
+  dependencies:
+    "@chainsafe/ssz" "0.9.4"
+    "@ethereumjs/common" "^3.1.1"
+    "@ethereumjs/rlp" "^4.0.1"
+    "@ethereumjs/util" "^8.0.5"
+    "@ethersproject/providers" "^5.7.2"
+    ethereum-cryptography "^1.1.2"
+
 "@ethereumjs/util@^8.0.0":
   version "8.0.2"
   resolved "https://registry.yarnpkg.com/@ethereumjs/util/-/util-8.0.2.tgz#b7348fc7253649b0f00685a94546c6eee1fad819"
@@ -1951,6 +1997,15 @@
     async "^3.2.4"
     ethereum-cryptography "^1.1.2"
 
+"@ethereumjs/util@^8.0.5":
+  version "8.0.5"
+  resolved "https://registry.yarnpkg.com/@ethereumjs/util/-/util-8.0.5.tgz#b9088fc687cc13f0c1243d6133d145dfcf3fe446"
+  integrity sha512-259rXKK3b3D8HRVdRmlOEi6QFvwxdt304hhrEAmpZhsj7ufXEOTIc9JRZPMnXatKjECokdLNBcDOFBeBSzAIaw==
+  dependencies:
+    "@chainsafe/ssz" "0.9.4"
+    "@ethereumjs/rlp" "^4.0.1"
+    ethereum-cryptography "^1.1.2"
+
 "@ethersproject/abi@5.4.1":
   version "5.4.1"
   resolved "https://registry.yarnpkg.com/@ethersproject/abi/-/abi-5.4.1.tgz#6ac28fafc9ef6f5a7a37e30356a2eb31fa05d39b"
@@ -2469,7 +2524,7 @@
     bech32 "1.1.4"
     ws "7.4.6"
 
-"@ethersproject/providers@5.7.2", "@ethersproject/providers@^5.7.0":
+"@ethersproject/providers@5.7.2", "@ethersproject/providers@^5.7.0", "@ethersproject/providers@^5.7.2":
   version "5.7.2"
   resolved "https://registry.yarnpkg.com/@ethersproject/providers/-/providers-5.7.2.tgz#f8b1a4f275d7ce58cf0a2eec222269a08beb18cb"
   integrity sha512-g34EWZ1WWAVgr4aptGlVBF8mhl3VWjv+8hoAnzStu8Ah22VHBsuGzP17eb6xDVRzw895G4W7vvx60lFFur/1Rg==
@@ -4300,6 +4355,17 @@
   resolved "https://registry.yarnpkg.com/@metamask/types/-/types-1.1.0.tgz#9bd14b33427932833c50c9187298804a18c2e025"
   integrity sha512-EEV/GjlYkOSfSPnYXfOosxa3TqYtIW3fhg6jdw+cok/OhMgNn4wCfbENFqjytrHMU2f7ZKtBAvtiP5V8H44sSw==
 
+"@metamask/utils@^5.0.0":
+  version "5.0.0"
+  resolved "https://registry.yarnpkg.com/@metamask/utils/-/utils-5.0.0.tgz#592dea36bb83d8cbf8f12ee236dd9fa49827e5e9"
+  integrity sha512-bsy7YiGxMo3rvyYbZc33yfMIfX4vVENFcxKctvNjLwCMx9d0xbLPT1T8yiqobb4NkZbwlacYEGxnv3GkTePGig==
+  dependencies:
+    "@ethereumjs/tx" "^4.1.1"
+    "@types/debug" "^4.1.7"
+    debug "^4.3.4"
+    semver "^7.3.8"
+    superstruct "^1.0.3"
+
 "@ngraveio/bc-ur@^1.1.5", "@ngraveio/bc-ur@^1.1.6":
   version "1.1.6"
   resolved "https://registry.yarnpkg.com/@ngraveio/bc-ur/-/bc-ur-1.1.6.tgz#8f8c75fff22f6a5e4dfbc5a6b540d7fe8f42cd39"
@@ -5443,6 +5509,13 @@
   dependencies:
     "@types/node" "*"
 
+"@types/debug@^4.1.7":
+  version "4.1.7"
+  resolved "https://registry.yarnpkg.com/@types/debug/-/debug-4.1.7.tgz#7cc0ea761509124709b8b2d1090d8f6c17aadb82"
+  integrity sha512-9AonUzyTjXXhEOa0DnqpzZi6VHlqKMswga9EXjpXnnqxwLtdvPPtlO8evrI5D9S6asFRCQ6v+wpiUKbw+vKqyg==
+  dependencies:
+    "@types/ms" "*"
+
 "@types/deep-freeze-strict@^1.1.0":
   version "1.1.0"
   resolved "https://registry.yarnpkg.com/@types/deep-freeze-strict/-/deep-freeze-strict-1.1.0.tgz#447a6a2576191344aa42310131dd3df5c41492c4"
@@ -5622,6 +5695,11 @@
   resolved "https://registry.yarnpkg.com/@types/mockery/-/mockery-1.4.30.tgz#25f07fa7340371c7ee0fb9239511a34e0a19d5b7"
   integrity sha512-uv53RrNdhbkV/3VmVCtfImfYCWC3GTTRn3R11Whni3EJ+gb178tkZBVNj2edLY5CMrB749dQi+SJkg87jsN8UQ==
 
+"@types/ms@*":
+  version "0.7.31"
+  resolved "https://registry.yarnpkg.com/@types/ms/-/ms-0.7.31.tgz#31b7ca6407128a3d2bbc27fe2d21b345397f6197"
+  integrity sha512-iiUgKzV9AuaEkZqkOLDIvlQiL6ltuZd9tGcW3gwpnX8JbuiuhFlEGmmFXEXkN50Cvq7Os88IY2v0dkDqXYWVgA==
+
 "@types/node@*":
   version "16.0.1"
   resolved "https://registry.yarnpkg.com/@types/node/-/node-16.0.1.tgz#70cedfda26af7a2ca073fdcc9beb2fff4aa693f8"
@@ -9031,6 +9109,11 @@ capture-exit@^2.0.0:
   dependencies:
     rsvp "^4.8.4"
 
+case@^1.6.3:
+  version "1.6.3"
+  resolved "https://registry.yarnpkg.com/case/-/case-1.6.3.tgz#0a4386e3e9825351ca2e6216c60467ff5f1ea1c9"
+  integrity sha512-mzDSXIPaFwVDvZAHqZ9VlbyF4yyXRuX6IvB06WvPYkqJVO24kX1PPhv9bfpKNFZyxYFmmgo03HUiD8iklmJYRQ==
+
 caseless@^0.12.0, caseless@~0.12.0:
   version "0.12.0"
   resolved "https://registry.yarnpkg.com/caseless/-/caseless-0.12.0.tgz#1b681c21ff84033c826543090689420d187151dc"
@@ -21996,7 +22079,7 @@ semver@^7.0.0, semver@^7.3.2, semver@^7.3.5:
   dependencies:
     lru-cache "^6.0.0"
 
-semver@^7.2.1:
+semver@^7.2.1, semver@^7.3.8:
   version "7.3.8"
   resolved "https://registry.yarnpkg.com/semver/-/semver-7.3.8.tgz#07a78feafb3f7b32347d725e33de7e2a2df67798"
   integrity sha512-NB1ctGL5rlHrPJtFDVIVzTyQylMLu9N9VICA6HSFJo8MCGVTMW6gfpicwKmmK/dAjTOrqu5l63JJOpDSrAis3A==
@@ -23067,6 +23150,11 @@ superagent@^3.8.1:
     qs "^6.5.1"
     readable-stream "^2.3.5"
 
+superstruct@^1.0.3:
+  version "1.0.3"
+  resolved "https://registry.yarnpkg.com/superstruct/-/superstruct-1.0.3.tgz#de626a5b49c6641ff4d37da3c7598e7a87697046"
+  integrity sha512-8iTn3oSS8nRGn+C2pgXSKPI3jmpm6FExNazNpjvqS6ZUJQCej3PUXEKM8NjHBOs54ExM+LPW/FBRhymrdcCiSg==
+
 supports-color@8.1.1, supports-color@^8.0.0, supports-color@^8.1.1:
   version "8.1.1"
   resolved "https://registry.yarnpkg.com/supports-color/-/supports-color-8.1.1.tgz#cd6fc17e28500cff56c1b86c0a7fd4a54a73005c"