diff --git a/src/libexpr/eval.cc b/src/libexpr/eval.cc
index a489686565e4..a65099a90155 100644
--- a/src/libexpr/eval.cc
+++ b/src/libexpr/eval.cc
@@ -326,6 +326,20 @@ static Symbol getName(const AttrName & name, EvalState & state, Env & env)
 }
 
 
+class BoehmDisableGC : public DisableGC {
+public:
+    BoehmDisableGC() {
+#if HAVE_BOEHMGC
+        GC_disable();
+#endif
+    };
+    virtual ~BoehmDisableGC() override {
+#if HAVE_BOEHMGC
+        GC_enable();
+#endif
+    };
+};
+
 static bool gcInitialised = false;
 
 void initGC()
@@ -349,6 +363,12 @@ void initGC()
 
     StackAllocator::defaultAllocator = &boehmGCStackAllocator;
 
+
+    /* Used to disable GC when entering coroutines on macOS */
+    DisableGC::create = []() {
+        return std::dynamic_pointer_cast<DisableGC>(std::make_shared<BoehmDisableGC>());
+    };
+
     /* Set the initial heap size to something fairly big (25% of
        physical RAM, up to a maximum of 384 MiB) so that in most cases
        we don't need to garbage collect at all.  (Collection has a
diff --git a/src/libexpr/tests/coro-gc.cc b/src/libexpr/tests/coro-gc.cc
index 6023b9b5e556..8d9585cc7c59 100644
--- a/src/libexpr/tests/coro-gc.cc
+++ b/src/libexpr/tests/coro-gc.cc
@@ -25,6 +25,7 @@ namespace nix {
 
     // Generate 2 objects, discard one, run gc,
     // see if one got collected and the other didn't
+    // GC is disabled inside coroutines on __APPLE__
     static void testFinalizerCalls() {
         bool* do_collect_collected = uncollectable_bool();
         bool* dont_collect_collected = uncollectable_bool();
@@ -37,7 +38,9 @@ namespace nix {
         GC_gcollect();
         GC_invoke_finalizers();
 
+#if !__APPLE__
         ASSERT_TRUE(*do_collect_collected);
+#endif
         ASSERT_FALSE(*dont_collect_collected);
         ASSERT_NE(nullptr, dont_collect);
     }
@@ -58,6 +61,10 @@ namespace nix {
         }
 
         auto source = sinkToSource([&](Sink& sink) {
+
+#if __APPLE__
+            ASSERT_TRUE(GC_is_disabled());
+#endif
             testFinalizerCalls();
 
             bool* dont_collect_inner_collected = uncollectable_bool();
@@ -71,6 +78,9 @@ namespace nix {
             }
             // pass control to main
             writeString("foo", sink);
+#if __APPLE__
+            ASSERT_TRUE(GC_is_disabled());
+#endif
 
             ASSERT_TRUE(*do_collect_inner_collected);
             ASSERT_FALSE(*dont_collect_inner_collected);
@@ -84,6 +94,7 @@ namespace nix {
         std::string foo = readString(*source);
         ASSERT_EQ(foo, "foo");
 
+        ASSERT_FALSE(GC_is_disabled());
         GC_gcollect();
         GC_invoke_finalizers();
 
diff --git a/src/libutil/serialise.cc b/src/libutil/serialise.cc
index c653db9d05e7..531100c017da 100644
--- a/src/libutil/serialise.cc
+++ b/src/libutil/serialise.cc
@@ -186,6 +186,10 @@ static DefaultStackAllocator defaultAllocatorSingleton;
 StackAllocator *StackAllocator::defaultAllocator = &defaultAllocatorSingleton;
 
 
+std::shared_ptr<DisableGC> (*DisableGC::create)() = []() {
+    return std::dynamic_pointer_cast<DisableGC>(std::make_shared<DisableGC>());
+};
+
 std::unique_ptr<FinishSink> sourceToSink(std::function<void(Source &)> fun)
 {
     struct SourceToSink : FinishSink
@@ -206,7 +210,11 @@ std::unique_ptr<FinishSink> sourceToSink(std::function<void(Source &)> fun)
             if (in.empty()) return;
             cur = in;
 
-            if (!coro)
+            if (!coro) {
+#if __APPLE__
+                /* Disable GC when entering the coroutine on macOS, since it doesn't find the main thread stack in this case */
+                auto disablegc = DisableGC::create();
+#endif
                 coro = coro_t::push_type(VirtualStackAllocator{}, [&](coro_t::pull_type & yield) {
                     LambdaSource source([&](char *out, size_t out_len) {
                         if (cur.empty()) {
@@ -223,17 +231,28 @@ std::unique_ptr<FinishSink> sourceToSink(std::function<void(Source &)> fun)
                     });
                     fun(source);
                 });
+            }
 
             if (!*coro) { abort(); }
 
-            if (!cur.empty()) (*coro)(false);
+            if (!cur.empty()) {
+#if __APPLE__
+                auto disablegc = DisableGC::create();
+#endif
+                (*coro)(false);
+            }
         }
 
         void finish() override
         {
             if (!coro) return;
             if (!*coro) abort();
-            (*coro)(true);
+            {
+#if __APPLE__
+                auto disablegc = DisableGC::create();
+#endif
+                (*coro)(true);
+            }
             if (*coro) abort();
         }
     };
@@ -264,18 +283,27 @@ std::unique_ptr<Source> sinkToSource(
 
         size_t read(char * data, size_t len) override
         {
-            if (!coro)
+            if (!coro) {
+#if __APPLE__
+                auto disablegc = DisableGC::create();
+#endif
                 coro = coro_t::pull_type(VirtualStackAllocator{}, [&](coro_t::push_type & yield) {
                     LambdaSink sink([&](std::string_view data) {
                         if (!data.empty()) yield(std::string(data));
                     });
                     fun(sink);
                 });
+            }
 
             if (!*coro) { eof(); abort(); }
 
             if (pos == cur.size()) {
-                if (!cur.empty()) (*coro)();
+                if (!cur.empty()) {
+#if __APPLE__
+                    auto disablegc = DisableGC::create();
+#endif
+                    (*coro)();
+                }
                 cur = coro->get();
                 pos = 0;
             }
diff --git a/src/libutil/serialise.hh b/src/libutil/serialise.hh
index 7da5b07fd335..fb1f14a3b1b2 100644
--- a/src/libutil/serialise.hh
+++ b/src/libutil/serialise.hh
@@ -501,4 +501,14 @@ struct StackAllocator {
     static StackAllocator *defaultAllocator;
 };
 
+/* Disabling GC when entering a coroutine (on macos).
+   ::create is to avoid boehm gc dependency in libutil.
+ */
+class DisableGC {
+public:
+    DisableGC() {};
+    virtual ~DisableGC() {};
+    static std::shared_ptr<DisableGC> (*create)();
+};
+
 }