diff --git a/pkgs/top-level/perl-packages.nix b/pkgs/top-level/perl-packages.nix
index 492e5baf70c5d8..9fb6c31575779b 100644
--- a/pkgs/top-level/perl-packages.nix
+++ b/pkgs/top-level/perl-packages.nix
@@ -255,6 +255,7 @@ let
       url = "mirror://cpan/authors/id/P/PL/PLICEASE/Alien-Build-2.37.tar.gz";
       hash = "sha256-MAC8vphIJkP3a7z/zkL9SPJMY6ZFf4qiwWlfSBrJ7VE=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     propagatedBuildInputs = [ CaptureTiny FFICheckLib FileWhich Filechdir PathTiny PkgConfig ];
     buildInputs = [ DevelHide Test2Suite ];
     meta = {
@@ -304,7 +305,7 @@ let
       hash = "sha256-c7RSRPC1w25TMsM1abgqGrLDPiY/HQB4XSADvK7GjbM=";
     };
     strictDeps = true;
-    nativeBuildInputs = [ pkgs.pkg-config ];
+    nativeBuildInputs = [ buildPackages.perl buildPackages.pkg-config ];
     propagatedBuildInputs = [ AlienBuild ];
     buildInputs = [ pkgs.libxml2 MojoDOM58 SortVersions Test2Suite URI ];
     meta = {
@@ -1585,6 +1586,7 @@ let
       url = "mirror://cpan/authors/id/E/ET/ETHER/B-Hooks-EndOfScope-0.24.tar.gz";
       hash = "sha256-A6o9/l0KpkcalvQ/6DGBedGXlNSmQHCPAoj5IW7HrMY=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     propagatedBuildInputs = [ ModuleImplementation SubExporterProgressive ];
     meta = {
       description = "Execute code after a scope finished compilation";
@@ -6406,6 +6408,7 @@ let
       url = "mirror://cpan/authors/id/D/DR/DROLSKY/DateTime-Locale-1.28.tar.gz";
       hash = "sha256-bGBNjFycJzm3jgU4pAIoO4Kx30GeYL7yCwSEPkWEut4=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     buildInputs = [ CPANMetaCheck FileShareDirInstall IPCSystemSimple PathTiny Test2PluginNoWarnings Test2Suite TestFileShareDir ];
     propagatedBuildInputs = [ FileShareDir ParamsValidationCompiler Specio namespaceautoclean ];
     meta = {
@@ -8794,6 +8797,7 @@ let
       url = "mirror://cpan/authors/id/A/AM/AMBS/ExtUtils-LibBuilder-0.08.tar.gz";
       hash = "sha256-xRFx4G3lMDnwvKHZemRx7DeUH/Weij0csXDr3SVztdI=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     perlPreHook = "export LD=$CC";
     meta = {
       description = "A tool to build C libraries";
@@ -9595,6 +9599,7 @@ let
       url = "mirror://cpan/authors/id/R/RE/REHSACK/File-ShareDir-1.118.tar.gz";
       hash = "sha256-O7KiC6Nd+VjcCk8jBvwF2QPYuMTePIvu/OF3OdKByVg=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     propagatedBuildInputs = [ ClassInspector ];
     buildInputs = [ FileShareDirInstall ];
     meta = {
@@ -13264,6 +13269,7 @@ let
       url = "mirror://cpan/authors/id/A/AL/ALINKE/Lingua-Translit-0.28.tar.gz";
       hash = "sha256-ET+R2PwsYwQ3FTpJ+3pSsCOvj2J47ZbAcLH2CCS46uE=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     doCheck = false;
     meta = {
       description = "Transliterates text between writing systems";
@@ -13433,6 +13439,7 @@ let
       url = "mirror://cpan/authors/id/R/RE/REHSACK/List-MoreUtils-0.430.tar.gz";
       hash = "sha256-Y7H3hCzULZtTjR404DMN5f8VWeTCc3NCUGQYJ29kZSc=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     propagatedBuildInputs = [ ExporterTiny ListMoreUtilsXS ];
     buildInputs = [ TestLeakTrace ];
     meta = {
@@ -13449,8 +13456,9 @@ let
       hash = "sha256-6M5G1XwXnuzYdYKT6UAP8wCq8g/v4KnRW5/iMCucskI=";
     };
     preConfigure = ''
-      export LD=$CC
+      makeMakerFlags="CC=$CC LD=$CC";
     '';
+    nativeBuildInputs = [ buildPackages.perl ];
     meta = {
       description = "Provide the stuff missing in List::Util in XS";
       homepage = "https://metacpan.org/release/List-MoreUtils-XS";
@@ -13465,6 +13473,7 @@ let
       url = "mirror://cpan/authors/id/D/DR/DROLSKY/List-SomeUtils-0.58.tar.gz";
       hash = "sha256-lur7NZM50ivyot5CEpiEejxA9qKLbUQAXQll2oalRp0=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     buildInputs = [ TestLeakTrace ];
     propagatedBuildInputs = [ ModuleImplementation ];
     meta = {
@@ -13481,6 +13490,7 @@ let
       url = "mirror://cpan/authors/id/P/PE/PEVANS/List-UtilsBy-0.11.tar.gz";
       hash = "sha256-+t30O0vCHbjkwOiaJuXyP+YmzeNJHsZRtqozhif1d1o=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     meta = {
       description = "Higher-order list utility functions";
       license = with lib.licenses; [ artistic1 gpl1Plus ];
@@ -15017,6 +15027,7 @@ let
       url = "mirror://cpan/authors/id/N/NE/NEZUMI/MIME-Charset-1.012.2.tar.gz";
       hash = "sha256-h4x3nAJWxZFma9BsDN5MDXgg7uuY/RGDCCrumh57HRM=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     meta = {
       description = "Charset Information for MIME";
       license = with lib.licenses; [ artistic1 gpl1Plus ];
@@ -15259,6 +15270,7 @@ let
       url = "mirror://cpan/authors/id/L/LE/LEONT/Module-Build-0.4231.tar.gz";
       hash = "sha256-fg9MaSwXQMGshOoU1+o9i8eYsvsmwJh3Ip4E9DCytxc=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     meta = {
       description = "Build and install Perl modules";
       license = with lib.licenses; [ artistic1 gpl1Plus ];
@@ -15334,6 +15346,7 @@ let
       url = "mirror://cpan/authors/id/L/LE/LEONT/Module-Build-Tiny-0.039.tar.gz";
       hash = "sha256-fVgP9qzgy+VVvza4bcjqIyWBUwy+quoJvMtXtVeX8Rw=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     buildInputs = [ FileShareDir ];
     propagatedBuildInputs = [ ExtUtilsHelpers ExtUtilsInstallPaths ];
     meta = {
@@ -15687,6 +15700,7 @@ let
       url = "mirror://cpan/authors/id/Z/ZE/ZEFRAM/Module-Runtime-0.016.tar.gz";
       hash = "sha256-aDAuxkaDNUfUEL4o4JZ223UAb0qlihHzvbRP/pnw8CQ=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     meta = {
       description = "Runtime module handling";
       license = with lib.licenses; [ artistic1 gpl1Plus ];
@@ -18226,7 +18240,7 @@ let
     preConfigure = ''
       mkdir openssl
       ln -s ${lib.getLib pkgs.openssl}/lib openssl
-      ln -s ${pkgs.openssl.bin}/bin openssl
+      ln -s ${buildPackages.openssl.bin}/bin openssl
       ln -s ${pkgs.openssl.dev}/include openssl
       export OPENSSL_PREFIX=$(realpath openssl)
     '';
@@ -18724,6 +18738,7 @@ let
       url = "mirror://cpan/authors/id/E/ET/ETHER/Package-Stash-0.39.tar.gz";
       hash = "sha256-kWX1VREuCASTzg6RKd4Ihtowslk/s1Oiq9HHay0mIbU=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     buildInputs = [ CPANMetaCheck TestFatal TestNeeds TestRequires ];
     propagatedBuildInputs = [ DistCheckConflicts ModuleImplementation ];
     meta = {
@@ -18849,7 +18864,10 @@ let
     };
     buildInputs = [ TestFatal TestRequires ];
     propagatedBuildInputs = [ ModuleImplementation ];
-    perlPreHook = "export LD=$CC";
+    nativeBuildInputs = [ buildPackages.perl ];
+    preConfigure = ''
+      makeMakerFlags="CC=$CC LD=$CC";
+    '';
     meta = {
       description = "Validate method/function parameters";
       homepage = "https://metacpan.org/release/Params-Validate";
@@ -19016,6 +19034,7 @@ let
       url = "mirror://cpan/authors/id/J/JT/JTBRAUN/Parse-RecDescent-1.967015.tar.gz";
       hash = "sha256-GUMzaky1TxeIpzPwgnwMVdtDENXq4V5UJjnJ3YVlbjc=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     meta = {
       description = "Generate Recursive-Descent Parsers";
       license = with lib.licenses; [ artistic1 gpl1Plus ];
@@ -20721,6 +20740,7 @@ let
       url = "mirror://cpan/authors/id/S/SA/SANKO/Readonly-2.05.tar.gz";
       hash = "sha256-SyNUJJGvAQ1EpcfIYSRHOKzHSrq65riDjTVN+xlGK14=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     buildInputs = [ ModuleBuildTiny ];
     meta = {
       description = "Facility for creating read-only scalars, arrays, hashes";
@@ -23980,6 +24000,10 @@ let
       url = "mirror://cpan/authors/id/L/LE/LEEJO/Test-LeakTrace-0.16.tar.gz";
       hash = "sha256-Xwie7ZFfHsjHQ/bSd3w+zQygHfL3ueEAONMWlSWD5AM=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
+    preConfigure = ''
+      makeMakerFlags="CC=$CC LD=$CC";
+    '';
     meta = {
       description = "Traces memory leaks";
       homepage = "https://metacpan.org/release/Test-LeakTrace";
@@ -25099,6 +25123,7 @@ let
     };
     # libbtparse.so: cannot open shared object file (aarch64 only)
     patches = [ ../development/perl-modules/TextBibTeX-use-lib-on-aarch64.patch ];
+    nativeBuildInputs = [ buildPackages.perl ];
     perlPreHook = "export LD=$CC";
     perlPostHook = lib.optionalString stdenv.isDarwin ''
       oldPath="$(pwd)/btparse/src/libbtparse.dylib"
@@ -25149,6 +25174,7 @@ let
       url = "mirror://cpan/authors/id/I/IS/ISHIGAKI/Text-CSV-2.00.tar.gz";
       hash = "sha256-jMvZGVgFIi2ZWEQRTQ5ZW7JM4Yj4UoTb8lYIAxHLssI=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     meta = {
       description = "Comma-separated values manipulator (using XS or PurePerl)";
       license = with lib.licenses; [ artistic1 gpl1Plus ];
@@ -25780,6 +25806,7 @@ let
       url = "mirror://cpan/authors/id/M/MA/MARKF/Test-utf8-1.02.tar.gz";
       hash = "sha256-34LwnFlAgwslpJ8cgWL6JNNx5gKIDt742aTUv9Zri9c=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     meta = {
       description = "Handy utf8 tests";
       homepage = "https://github.com/2shortplanks/Test-utf8/tree";
@@ -27320,6 +27347,10 @@ let
     buildInputs = [ AlienBuild AlienLibxml2 ]
       ++ lib.optionals stdenv.isDarwin (with pkgs; [ libiconv zlib ]);
     propagatedBuildInputs = [ XMLSAX ];
+    nativeBuildInputs = [ buildPackages.perl ];
+    preConfigure = ''
+      makeMakerFlags="CC=$CC LD=$LD";
+    '';
     meta = {
       description = "Perl Binding for libxml2";
       license = with lib.licenses; [ artistic1 gpl1Plus ];
@@ -27347,7 +27378,18 @@ let
       url = "mirror://cpan/authors/id/S/SH/SHLOMIF/XML-LibXSLT-1.99.tar.gz";
       hash = "sha256-En4XqHf7YeR7nouHv42q0xM5pioAEh+XUdUitDiw9/A=";
     };
-    nativeBuildInputs = [ pkgs.pkg-config ];
+    patches = lib.optional (!stdenv.buildPlatform.canExecute stdenv.hostPlatform)
+      (fetchpatch {
+        # Remove the 'have_library()' check. It breaks cross compilation.
+        # The checked for libxslt and libexslt are pulled in via buildInputs and
+        # therefore do exist, anyway.
+        url = "https://raw.githubusercontent.com/void-linux/void-packages/5c37bd5f21c4be14761d85c98c996b2d11ae80c4/srcpkgs/perl-XML-LibXSLT/patches/fix-cross-remove-have_library.patch";
+        hash = "sha256-ejSdl3HVrMgWLmJK9YEioeheTVJ1J4OHMiQP1oZAsqI=";
+      });
+    preConfigure = lib.optionalString (!stdenv.buildPlatform.canExecute stdenv.hostPlatform) ''
+      makeMakerFlags="CC=$CC LD=$LD INC=-I${pkgs.libxml2.dev}/include/libxml2";
+    '';
+    nativeBuildInputs = [ buildPackages.perl buildPackages.pkg-config ];
     buildInputs = [ pkgs.zlib pkgs.libxml2 pkgs.libxslt ];
     propagatedBuildInputs = [ XMLLibXML ];
     meta = {
@@ -27511,6 +27553,7 @@ let
       url = "mirror://cpan/authors/id/G/GR/GRANTM/XML-SAX-1.02.tar.gz";
       hash = "sha256-RQbDhwQ6pqd7RV8A9XQJ83IKp+VTSVqyU1JjtO0eoSo=";
     };
+    nativeBuildInputs = [ buildPackages.perl ];
     propagatedBuildInputs = [ XMLNamespaceSupport XMLSAXBase ];
     postInstall = ''
       perl -MXML::SAX -e "XML::SAX->add_parser(q(XML::SAX::PurePerl))->save_parsers()"