diff --git a/pkgs/development/libraries/science/math/faiss/default.nix b/pkgs/development/libraries/science/math/faiss/default.nix
index 9b7b4d268197767..ac19356d1a73a06 100644
--- a/pkgs/development/libraries/science/math/faiss/default.nix
+++ b/pkgs/development/libraries/science/math/faiss/default.nix
@@ -63,6 +63,15 @@ stdenv.mkDerivation {
     })
   ];
 
+  postPatch = ''
+    # Remove the following substituteInPlace when updating
+    # to a release that contains change from PR
+    # https://github.com/facebookresearch/faiss/issues/3239
+    # that fixes building faiss with swig 4.2.x
+    substituteInPlace faiss/python/swigfaiss.swig \
+      --replace-fail '#ifdef SWIGWORDSIZE64' '#if (__SIZEOF_LONG__ == 8)'
+  '';
+
   buildInputs = [
     blas
     swig
diff --git a/pkgs/development/tools/misc/swig/4.nix b/pkgs/development/tools/misc/swig/4.nix
index 6b6d1bc02db9895..bae53ad42f9d374 100644
--- a/pkgs/development/tools/misc/swig/4.nix
+++ b/pkgs/development/tools/misc/swig/4.nix
@@ -1,19 +1,19 @@
-{ lib, stdenv, fetchFromGitHub, autoconf, automake, libtool, bison, pcre }:
+{ lib, stdenv, fetchFromGitHub, autoconf, automake, libtool, bison, pcre2 }:
 
-stdenv.mkDerivation rec {
+stdenv.mkDerivation (finalAttrs: {
   pname = "swig";
-  version = "4.0.2";
+  version = "4.2.1";
 
   src = fetchFromGitHub {
     owner = "swig";
     repo = "swig";
-    rev = "rel-${version}";
-    sha256 = "12vlps766xvwck8q0i280s8yx21qm2dxl34710ybpmz3c1cfdjsc";
+    rev = "v${finalAttrs.version}";
+    hash = "sha256-VlUsiRZLScmbC7hZDzKqUr9481YXVwo0eXT/jy6Fda8=";
   };
 
-  PCRE_CONFIG = "${pcre.dev}/bin/pcre-config";
+  PCRE_CONFIG = "${pcre2.dev}/bin/pcre-config";
   nativeBuildInputs = [ autoconf automake libtool bison ];
-  buildInputs = [ pcre ];
+  buildInputs = [ pcre2 ];
 
   configureFlags = [ "--without-tcl" ];
 
@@ -26,12 +26,14 @@ stdenv.mkDerivation rec {
     ./autogen.sh
   '';
 
-  meta = with lib; {
-    description = "SWIG, an interface compiler that connects C/C++ code to higher-level languages";
+  meta = {
+    changelog = "https://github.com/swig/swig/blob/${finalAttrs.src.rev}/CHANGES.current";
+    description = "Interface compiler that connects C/C++ code to higher-level languages";
     homepage = "https://swig.org/";
-    # Different types of licenses available: http://www.swig.org/Release/LICENSE .
-    license = licenses.gpl3Plus;
-    maintainers = with maintainers; [ orivej ];
-    platforms = with platforms; linux ++ darwin;
+    # Different types of licenses available: https://www.swig.org/Release/LICENSE .
+    license = lib.licenses.gpl3Plus;
+    maintainers = with lib.maintainers; [ orivej ];
+    mainProgram = "swig";
+    platforms = with lib.platforms; linux ++ darwin;
   };
-}
+})