diff --git a/monai/bundle/scripts.py b/monai/bundle/scripts.py
index 44e92038b6..637fbb12d8 100644
--- a/monai/bundle/scripts.py
+++ b/monai/bundle/scripts.py
@@ -625,8 +625,11 @@ def run(
 
     Args:
         run_id: ID name of the expected config expression to run, default to "run".
+            to run the config, the target config must contain this ID.
         init_id: ID name of the expected config expression to initialize before running, default to "initialize".
+            it's optional for both configs and this `run` function.
         final_id: ID name of the expected config expression to finalize after running, default to "finalize".
+            it's optional for both configs and this `run` function.
         meta_file: filepath of the metadata file, if it is a list of file paths, the content of them will be merged.
             Default to "configs/metadata.json", which is commonly used for bundles in MONAI model zoo.
         config_file: filepath of the config file, if `None`, must be provided in `args_file`.
diff --git a/monai/bundle/workflows.py b/monai/bundle/workflows.py
index 5a5380057e..48e2944798 100644
--- a/monai/bundle/workflows.py
+++ b/monai/bundle/workflows.py
@@ -148,8 +148,11 @@ class ConfigWorkflow(BundleWorkflow):
 
     Args:
         run_id: ID name of the expected config expression to run, default to "run".
+            to run the config, the target config must contain this ID.
         init_id: ID name of the expected config expression to initialize before running, default to "initialize".
+            allow a config to have no `initialize` logic and the ID.
         final_id: ID name of the expected config expression to finalize after running, default to "finalize".
+            allow a config to have no `finalize` logic and the ID.
         meta_file: filepath of the metadata file, if it is a list of file paths, the content of them will be merged.
             Default to "configs/metadata.json", which is commonly used for bundles in MONAI model zoo.
         config_file: filepath of the config file, if it is a list of file paths, the content of them will be merged.
@@ -235,6 +238,8 @@ def run(self) -> Any:
         Run the bundle workflow, it can be a training, evaluation or inference.
 
         """
+        if self.run_id not in self.parser:
+            raise ValueError(f"run ID '{self.run_id}' doesn't exist in the config file.")
         return self._run_expr(id=self.run_id)
 
     def finalize(self) -> Any:
diff --git a/tests/test_integration_bundle_run.py b/tests/test_integration_bundle_run.py
index 2018ca801e..74ac93bc27 100644
--- a/tests/test_integration_bundle_run.py
+++ b/tests/test_integration_bundle_run.py
@@ -66,6 +66,9 @@ def test_tiny(self):
         # test both CLI entry "run" and "run_workflow"
         command_line_tests(cmd + ["run", "training", "--config_file", config_file])
         command_line_tests(cmd + ["run_workflow", "--run_id", "training", "--config_file", config_file])
+        with self.assertRaises(RuntimeError):
+            # test wrong run_id="run"
+            command_line_tests(cmd + ["run", "run", "--config_file", config_file])
 
     @parameterized.expand([TEST_CASE_1, TEST_CASE_2])
     def test_shape(self, config_file, expected_shape):