diff --git a/newsfragments/4317.added.md b/newsfragments/4317.added.md
new file mode 100644
index 00000000000..99849236101
--- /dev/null
+++ b/newsfragments/4317.added.md
@@ -0,0 +1 @@
+Implement `PartialEq` for `Bound<'py, PyInt>` with `u8`, `u16`, `u32`, `u64`, `u128`, `usize`, `i8`, `i16`, `i32`, `i64`, `i128` and `isize`.
diff --git a/src/types/num.rs b/src/types/num.rs
index 517e769742b..f33d85f4a1c 100644
--- a/src/types/num.rs
+++ b/src/types/num.rs
@@ -1,4 +1,6 @@
-use crate::{ffi, PyAny};
+use super::any::PyAnyMethods;
+
+use crate::{ffi, instance::Bound, PyAny};
 
 /// Represents a Python `int` object.
 ///
@@ -17,3 +19,113 @@ pyobject_native_type_core!(PyInt, pyobject_native_static_type_object!(ffi::PyLon
 /// Deprecated alias for [`PyInt`].
 #[deprecated(since = "0.23.0", note = "use `PyInt` instead")]
 pub type PyLong = PyInt;
+
+macro_rules! int_compare {
+    ($rust_type: ty) => {
+        impl PartialEq<$rust_type> for Bound<'_, PyInt> {
+            #[inline]
+            fn eq(&self, other: &$rust_type) -> bool {
+                if let Ok(value) = self.extract::<$rust_type>() {
+                    value == *other
+                } else {
+                    false
+                }
+            }
+        }
+        impl PartialEq<Bound<'_, PyInt>> for $rust_type {
+            #[inline]
+            fn eq(&self, other: &Bound<'_, PyInt>) -> bool {
+                if let Ok(value) = other.extract::<$rust_type>() {
+                    value == *self
+                } else {
+                    false
+                }
+            }
+        }
+    };
+}
+
+int_compare!(i8);
+int_compare!(u8);
+int_compare!(i16);
+int_compare!(u16);
+int_compare!(i32);
+int_compare!(u32);
+int_compare!(i64);
+int_compare!(u64);
+int_compare!(i128);
+int_compare!(u128);
+int_compare!(isize);
+int_compare!(usize);
+
+#[cfg(test)]
+mod tests {
+    use super::PyInt;
+    use crate::{types::PyAnyMethods, IntoPy, Python};
+
+    #[test]
+    fn test_partial_eq() {
+        Python::with_gil(|py| {
+            let v_i8 = 123i8;
+            let v_u8 = 123i8;
+            let v_i16 = 123i16;
+            let v_u16 = 123u16;
+            let v_i32 = 123i32;
+            let v_u32 = 123u32;
+            let v_i64 = 123i64;
+            let v_u64 = 123u64;
+            let v_i128 = 123i128;
+            let v_u128 = 123u128;
+            let v_isize = 123isize;
+            let v_usize = 123usize;
+            let obj = 123_i64.into_py(py).downcast_bound(py).unwrap().clone();
+            assert_eq!(v_i8, obj);
+            assert_eq!(obj, v_i8);
+
+            assert_eq!(v_u8, obj);
+            assert_eq!(obj, v_u8);
+
+            assert_eq!(v_i16, obj);
+            assert_eq!(obj, v_i16);
+
+            assert_eq!(v_u16, obj);
+            assert_eq!(obj, v_u16);
+
+            assert_eq!(v_i32, obj);
+            assert_eq!(obj, v_i32);
+
+            assert_eq!(v_u32, obj);
+            assert_eq!(obj, v_u32);
+
+            assert_eq!(v_i64, obj);
+            assert_eq!(obj, v_i64);
+
+            assert_eq!(v_u64, obj);
+            assert_eq!(obj, v_u64);
+
+            assert_eq!(v_i128, obj);
+            assert_eq!(obj, v_i128);
+
+            assert_eq!(v_u128, obj);
+            assert_eq!(obj, v_u128);
+
+            assert_eq!(v_isize, obj);
+            assert_eq!(obj, v_isize);
+
+            assert_eq!(v_usize, obj);
+            assert_eq!(obj, v_usize);
+
+            let big_num = (u8::MAX as u16) + 1;
+            let big_obj = big_num
+                .into_py(py)
+                .into_bound(py)
+                .downcast_into::<PyInt>()
+                .unwrap();
+
+            for x in 0u8..=u8::MAX {
+                assert_ne!(x, big_obj);
+                assert_ne!(big_obj, x);
+            }
+        });
+    }
+}
diff --git a/tests/test_class_attributes.rs b/tests/test_class_attributes.rs
index 9e544211c3c..a2e099549c0 100644
--- a/tests/test_class_attributes.rs
+++ b/tests/test_class_attributes.rs
@@ -224,7 +224,7 @@ macro_rules! test_case {
                 let struct_obj = struct_class.call0().unwrap();
                 assert!(struct_obj.setattr($renamed_field_name, 2).is_ok());
                 let attr = struct_obj.getattr($renamed_field_name).unwrap();
-                assert_eq!(2, attr.extract().unwrap());
+                assert_eq!(2, attr.extract::<u8>().unwrap());
             });
         }
     };