diff --git a/src/array.rs b/src/array.rs
index eee82a71f..1e2e56343 100644
--- a/src/array.rs
+++ b/src/array.rs
@@ -298,15 +298,6 @@ impl<T, D> PyArray<T, D> {
         self.len() == 0
     }
 
-    fn strides_usize(&self) -> &[usize] {
-        let n = self.ndim();
-        let ptr = self.as_array_ptr();
-        unsafe {
-            let p = (*ptr).strides;
-            slice::from_raw_parts(p as *const _, n)
-        }
-    }
-
     /// Returns the pointer to the first element of the inner array.
     pub(crate) unsafe fn data(&self) -> *mut T {
         let ptr = self.as_array_ptr();
@@ -318,6 +309,16 @@ impl<T, D> PyArray<T, D> {
     }
 }
 
+struct InvertedAxises(Vec<Axis>);
+
+impl InvertedAxises {
+    fn invert<S: RawData, D: Dimension>(self, array: &mut ArrayBase<S, D>) {
+        for axis in self.0 {
+            array.invert_axis(axis);
+        }
+    }
+}
+
 impl<T: Element, D: Dimension> PyArray<T, D> {
     /// Same as [shape](#method.shape), but returns `D`
     #[inline(always)]
@@ -325,13 +326,33 @@ impl<T: Element, D: Dimension> PyArray<T, D> {
         D::from_dimension(&Dim(self.shape())).expect("PyArray::dims different dimension")
     }
 
-    fn ndarray_shape(&self) -> StrideShape<D> {
+    fn ndarray_shape_ptr(&self) -> (StrideShape<D>, *mut T, InvertedAxises) {
+        const ERR_MSG: &str = "PyArray::ndarray_shape: dimension mismatching";
+        let shape_slice = self.shape();
         let shape: Shape<_> = Dim(self.dims()).into();
-        let size = mem::size_of::<T>();
-        let mut st = D::from_dimension(&Dim(self.strides_usize()))
-            .expect("PyArray::ndarray_shape: dimension mismatching");
-        st.slice_mut().iter_mut().for_each(|e| *e /= size);
-        shape.strides(st)
+        let sizeof_t = mem::size_of::<T>();
+        let strides = self.strides();
+        let mut new_strides = D::zeros(strides.len());
+        let mut data_ptr = unsafe { self.data() };
+        let mut inverted_axises = vec![];
+        for i in 0..strides.len() {
+            // TODO(kngwyu): Replace this hacky negative strides support with
+            // a proper constructor, when it's implemented.
+            // See https://github.com/rust-ndarray/ndarray/issues/842 for more.
+            if strides[i] < 0 {
+                // Move the pointer to the start position
+                let offset = strides[i] * (shape_slice[i] as isize - 1) / sizeof_t as isize;
+                unsafe {
+                    data_ptr = data_ptr.offset(offset);
+                }
+                new_strides[i] = (-strides[i]) as usize / sizeof_t;
+                inverted_axises.push(Axis(i));
+            } else {
+                new_strides[i] = strides[i] as usize / sizeof_t;
+            }
+        }
+        let st = D::from_dimension(&Dim(new_strides)).expect(ERR_MSG);
+        (shape.strides(st), data_ptr, InvertedAxises(inverted_axises))
     }
 
     /// Creates a new uninitialized PyArray in python heap.
@@ -632,7 +653,10 @@ impl<T: Element, D: Dimension> PyArray<T, D> {
     /// If the internal array is not readonly and can be mutated from Python code,
     /// holding the `ArrayView` might cause undefined behavior.
     pub unsafe fn as_array(&self) -> ArrayView<'_, T, D> {
-        ArrayView::from_shape_ptr(self.ndarray_shape(), self.data())
+        let (shape, ptr, inverted_axises) = self.ndarray_shape_ptr();
+        let mut res = ArrayView::from_shape_ptr(shape, ptr);
+        inverted_axises.invert(&mut res);
+        res
     }
 
     /// Returns the internal array as `ArrayViewMut`. See also [`as_array`](#method.as_array).
@@ -641,7 +665,10 @@ impl<T: Element, D: Dimension> PyArray<T, D> {
     /// If another reference to the internal data exists(e.g., `&[T]` or `ArrayView`),
     /// it might cause undefined behavior.
     pub unsafe fn as_array_mut(&self) -> ArrayViewMut<'_, T, D> {
-        ArrayViewMut::from_shape_ptr(self.ndarray_shape(), self.data())
+        let (shape, ptr, inverted_axises) = self.ndarray_shape_ptr();
+        let mut res = ArrayViewMut::from_shape_ptr(shape, ptr);
+        inverted_axises.invert(&mut res);
+        res
     }
 
     /// Get a copy of `PyArray` as
diff --git a/tests/array.rs b/tests/array.rs
index d69f9b474..7e2e964bf 100644
--- a/tests/array.rs
+++ b/tests/array.rs
@@ -220,3 +220,17 @@ fn array_cast() {
     let arr_i32: &PyArray2<i32> = arr_f64.cast(false).unwrap();
     assert_eq!(arr_i32.readonly().as_array(), array![[1, 2, 3], [1, 2, 3]]);
 }
+
+#[test]
+fn handle_negative_strides() {
+    let gil = pyo3::Python::acquire_gil();
+    let py = gil.python();
+    let arr = array![[2, 3], [4, 5u32]];
+    let pyarr = arr.to_pyarray(py);
+    let negstr_pyarr: &numpy::PyArray2<u32> = py
+        .eval("a[::-1]", Some([("a", pyarr)].into_py_dict(py)), None)
+        .unwrap()
+        .downcast()
+        .unwrap();
+    assert_eq!(negstr_pyarr.to_owned_array(), arr.slice(s![..;-1, ..]));
+}