diff --git a/ext/DynamicPPLEnzymeCoreExt.jl b/ext/DynamicPPLEnzymeCoreExt.jl
index f83d6e8f7..ceb3f4981 100644
--- a/ext/DynamicPPLEnzymeCoreExt.jl
+++ b/ext/DynamicPPLEnzymeCoreExt.jl
@@ -10,4 +10,9 @@ end
 
 @inline EnzymeCore.EnzymeRules.inactive_type(::Type{<:DynamicPPL.SamplingContext}) = true
 
+# Mark istrans as having 0 derivative. The `nothing` return value is not significant, Enzyme
+# only checks whether such a method exists, and never runs it.
+@inline EnzymeCore.EnzymeRules.inactive_noinl(::typeof(DynamicPPL.istrans), args...) =
+    nothing
+
 end