diff --git a/configs/resources.config b/configs/resources.config index 594a032..37b6eaa 100644 --- a/configs/resources.config +++ b/configs/resources.config @@ -4,18 +4,18 @@ params { "GRCh37" { fasta = "${params.resource_dir}/GRCh37/Sequence/genome.fa" gatk_known_sites = [ - "${params.resource_dir}/GRCh37/Annotation/1000G_phase1.indels.b37.vcf.gz", - "${params.resource_dir}/GRCh37/Annotation/dbsnp_138.b37.vcf.gz", - "${params.resource_dir}/GRCh37/Annotation/Mills_and_1000G_gold_standard.indels.b37.vcf.gz" + "${params.resource_dir}/GRCh37/Annotation/1000G/1000G_phase1.indels.b37.vcf.gz", + "${params.resource_dir}/GRCh37/Annotation/dbsnp/dbsnp_138.b37.vcf.gz", + "${params.resource_dir}/GRCh37/Annotation/1000G/Mills_and_1000G_gold_standard.indels.b37.vcf.gz" ] - dbsnp = "${params.resource_dir}/GRCh37/Annotation/dbsnp_138.b37.vcf.gz" - dbnsfp = "${params.resource_dir}/GRCh37/Annotation/dbNSFP2.9.3.txt.gz" - cosmic = "${params.resource_dir}/GRCh37/Annotation/CosmicCodingMuts_v80.vcf.gz" - gonl = "${params.resource_dir}/GRCh37/Annotation/gonl.snps_indels.r5.vcf.gz" + dbsnp = "${params.resource_dir}/GRCh37/Annotation/dbsnp/dbsnp_138.b37.vcf.gz" + dbnsfp = "${params.resource_dir}/GRCh37/Annotation/dbNSFP/dbNSFP2.9.3.txt.gz" + cosmic = "${params.resource_dir}/GRCh37/Annotation/Cosmic/CosmicCodingMuts_v80.vcf.gz" + gonl = "${params.resource_dir}/GRCh37/Annotation/GoNL/gonl.snps_indels.r5.vcf.gz" interval_list = "${params.resource_dir}/GRCh37/Sequence/genome.interval_list" freec_chr_len = "${params.resource_dir}/GRCh37/Sequence/genome.len" freec_chr_files = "${params.resource_dir}/GRCh37/Sequence/chr_files" - freec_mappability = "${params.resource_dir}/GRCh37/Annotation/out100m2_hg19.gem" + freec_mappability = "${params.resource_dir}/GRCh37/Annotation/misc/out100m2_hg19.gem" } "UMD3.1" { fasta = "${params.resource_dir}/UMD3.1/Sequence/Bos_taurus.UMD3.1.dna.toplevel.fa" diff --git a/configs/test-run.config b/configs/test-run.config index 536fda0..4d84edf 100644 --- a/configs/test-run.config +++ b/configs/test-run.config @@ -1,7 +1,7 @@ /* Always include process and resources config */ -includeConfig '/home/cog/sboymans/scripts/NF-IAP_dev/configs/nextflow.config' -includeConfig '/home/cog/sboymans/scripts/NF-IAP_dev/configs/process.config' -includeConfig '/home/cog/sboymans/scripts/NF-IAP_dev/configs/resources.config' +includeConfig '/home/cog/sboymans/scripts/NF-IAP/configs/nextflow.config' +includeConfig '/home/cog/sboymans/scripts/NF-IAP/configs/process.config' +includeConfig '/home/cog/sboymans/scripts/NF-IAP/configs/resources.config' params { help = false @@ -11,12 +11,12 @@ params { vcf_path = '' genome = 'GRCh37' - premapQC = false - postmapQC = false + premapQC = true + postmapQC = true germlineCalling = true variantFiltration = true variantAnnotation = true svCalling = false cnvCalling = false - splitVCF = true + //splitVCF = true }