diff --git a/packages/block-editor/src/components/block-variation-picker/index.js b/packages/block-editor/src/components/block-variation-picker/index.js
index ecdf8b23bec3f..f3687a305e84f 100644
--- a/packages/block-editor/src/components/block-variation-picker/index.js
+++ b/packages/block-editor/src/components/block-variation-picker/index.js
@@ -64,8 +64,7 @@ function BlockVariationPicker( {
 			{ allowSkip && (
 				<div className="block-editor-block-variation-picker__skip">
 					<Button
-						// TODO: Switch to `true` (40px size) if possible
-						__next40pxDefaultSize={ false }
+						__next40pxDefaultSize
 						variant="link"
 						onClick={ () => onSelect() }
 					>
diff --git a/packages/block-editor/src/components/block-variation-transforms/index.js b/packages/block-editor/src/components/block-variation-transforms/index.js
index 97a3f98054184..79cf891112629 100644
--- a/packages/block-editor/src/components/block-variation-transforms/index.js
+++ b/packages/block-editor/src/components/block-variation-transforms/index.js
@@ -35,8 +35,8 @@ function VariationsButtons( {
 			</VisuallyHidden>
 			{ variations.map( ( variation ) => (
 				<Button
-					// TODO: Switch to `true` (40px size) if possible
-					__next40pxDefaultSize={ false }
+					__next40pxDefaultSize
+					size="compact"
 					key={ variation.name }
 					icon={ <BlockIcon icon={ variation.icon } showColors /> }
 					isPressed={ selectedValue === variation.name }
diff --git a/packages/block-editor/src/components/button-block-appender/content.scss b/packages/block-editor/src/components/button-block-appender/content.scss
index e462278c07c10..f5486d3f6f608 100644
--- a/packages/block-editor/src/components/button-block-appender/content.scss
+++ b/packages/block-editor/src/components/button-block-appender/content.scss
@@ -8,11 +8,6 @@
 	color: $gray-900;
 	box-shadow: inset 0 0 0 $border-width $gray-900;
 
-	// Needs specificity to override button styles.
-	&.components-button.components-button {
-		padding: $grid-unit-15;
-	}
-
 	.is-dark-theme & {
 		color: $light-gray-placeholder;
 		box-shadow: inset 0 0 0 $border-width $light-gray-placeholder;
diff --git a/packages/block-editor/src/components/button-block-appender/index.js b/packages/block-editor/src/components/button-block-appender/index.js
index c4a6854c6d6cc..53b15e2fd2cfd 100644
--- a/packages/block-editor/src/components/button-block-appender/index.js
+++ b/packages/block-editor/src/components/button-block-appender/index.js
@@ -60,8 +60,7 @@ function ButtonBlockAppender(
 
 				return (
 					<Button
-						// TODO: Switch to `true` (40px size) if possible
-						__next40pxDefaultSize={ false }
+						__next40pxDefaultSize
 						ref={ mergedInserterButtonRef }
 						onFocus={ onFocus }
 						tabIndex={ tabIndex }
diff --git a/packages/block-editor/src/components/colors-gradients/dropdown.js b/packages/block-editor/src/components/colors-gradients/dropdown.js
index d3cf59a2a5e6e..71b27c06e7ccf 100644
--- a/packages/block-editor/src/components/colors-gradients/dropdown.js
+++ b/packages/block-editor/src/components/colors-gradients/dropdown.js
@@ -88,11 +88,7 @@ const renderToggle =
 		};
 
 		return (
-			<Button
-				// TODO: Switch to `true` (40px size) if possible
-				__next40pxDefaultSize={ false }
-				{ ...toggleProps }
-			>
+			<Button __next40pxDefaultSize { ...toggleProps }>
 				<LabeledColorIndicator
 					colorValue={ colorValue }
 					label={ label }
diff --git a/packages/block-editor/src/components/global-styles/color-panel.js b/packages/block-editor/src/components/global-styles/color-panel.js
index 87c19adedbb27..a55a7b331bd0d 100644
--- a/packages/block-editor/src/components/global-styles/color-panel.js
+++ b/packages/block-editor/src/components/global-styles/color-panel.js
@@ -239,11 +239,7 @@ function ColorPanelDropdown( {
 					};
 
 					return (
-						<Button
-							// TODO: Switch to `true` (40px size) if possible
-							__next40pxDefaultSize={ false }
-							{ ...toggleProps }
-						>
+						<Button __next40pxDefaultSize { ...toggleProps }>
 							<LabeledColorIndicators
 								indicators={ indicators }
 								label={ label }
diff --git a/packages/block-editor/src/components/global-styles/filters-panel.js b/packages/block-editor/src/components/global-styles/filters-panel.js
index de6e58b3334f1..581661e0c8407 100644
--- a/packages/block-editor/src/components/global-styles/filters-panel.js
+++ b/packages/block-editor/src/components/global-styles/filters-panel.js
@@ -190,8 +190,7 @@ export default function FiltersPanel( {
 							return (
 								<ItemGroup isBordered isSeparated>
 									<Button
-										// TODO: Switch to `true` (40px size) if possible
-										__next40pxDefaultSize={ false }
+										__next40pxDefaultSize
 										{ ...toggleProps }
 									>
 										<LabeledColorIndicator
diff --git a/packages/block-editor/src/components/global-styles/shadow-panel-components.js b/packages/block-editor/src/components/global-styles/shadow-panel-components.js
index 1ed367e3c3ad0..1cfdff0be286e 100644
--- a/packages/block-editor/src/components/global-styles/shadow-panel-components.js
+++ b/packages/block-editor/src/components/global-styles/shadow-panel-components.js
@@ -11,6 +11,7 @@ import {
 	FlexItem,
 	Dropdown,
 	Composite,
+	Tooltip,
 } from '@wordpress/components';
 import { useMemo } from '@wordpress/element';
 import { shadow as shadowIcon, Icon, check } from '@wordpress/icons';
@@ -42,8 +43,7 @@ export function ShadowPopoverContainer( { shadow, onShadowChange, settings } ) {
 				/>
 				<div className="block-editor-global-styles__clear-shadow">
 					<Button
-						// TODO: Switch to `true` (40px size) if possible
-						__next40pxDefaultSize={ false }
+						__next40pxDefaultSize
 						variant="tertiary"
 						onClick={ () => onShadowChange( undefined ) }
 					>
@@ -80,32 +80,31 @@ export function ShadowPresets( { presets, activeShadow, onSelect } ) {
 
 export function ShadowIndicator( { type, label, isActive, onSelect, shadow } ) {
 	return (
-		<Composite.Item
-			role="option"
-			aria-label={ label }
-			aria-selected={ isActive }
-			className={ clsx( 'block-editor-global-styles__shadow__item', {
-				'is-active': isActive,
-			} ) }
-			render={
-				<Button
-					// TODO: Switch to `true` (40px size) if possible
-					__next40pxDefaultSize={ false }
-					className={ clsx(
-						'block-editor-global-styles__shadow-indicator',
-						{
-							unset: type === 'unset',
-						}
-					) }
-					onClick={ onSelect }
-					label={ label }
-					style={ { boxShadow: shadow } }
-					showTooltip
-				>
-					{ isActive && <Icon icon={ check } /> }
-				</Button>
-			}
-		/>
+		<Tooltip text={ label }>
+			<Composite.Item
+				role="option"
+				aria-label={ label }
+				aria-selected={ isActive }
+				className={ clsx( 'block-editor-global-styles__shadow__item', {
+					'is-active': isActive,
+				} ) }
+				render={
+					<button
+						className={ clsx(
+							'block-editor-global-styles__shadow-indicator',
+							{
+								unset: type === 'unset',
+							}
+						) }
+						onClick={ onSelect }
+						style={ { boxShadow: shadow } }
+						aria-label={ label }
+					>
+						{ isActive && <Icon icon={ check } /> }
+					</button>
+				}
+			/>
+		</Tooltip>
 	);
 }
 
@@ -143,11 +142,7 @@ function renderShadowToggle() {
 		};
 
 		return (
-			<Button
-				// TODO: Switch to `true` (40px size) if possible
-				__next40pxDefaultSize={ false }
-				{ ...toggleProps }
-			>
+			<Button __next40pxDefaultSize { ...toggleProps }>
 				<HStack justify="flex-start">
 					<Icon
 						className="block-editor-global-styles__toggle-icon"
diff --git a/packages/block-editor/src/components/global-styles/style.scss b/packages/block-editor/src/components/global-styles/style.scss
index 3ba4f81d09daf..e0782fdb01b1d 100644
--- a/packages/block-editor/src/components/global-styles/style.scss
+++ b/packages/block-editor/src/components/global-styles/style.scss
@@ -37,10 +37,15 @@
 
 // These styles are similar to the color palette.
 .block-editor-global-styles__shadow-indicator {
+	appearance: none;
+	background: none;
 	color: $gray-800;
 	border: $gray-200 $border-width solid;
 	border-radius: $radius-small;
 	cursor: pointer;
+	display: inline-flex;
+	align-items: center;
+
 	padding: 0;
 
 	height: $button-size-small + 2 * $border-width;
diff --git a/packages/block-library/src/group/editor.scss b/packages/block-library/src/group/editor.scss
index 11beecbab0eb6..739a9cd0cf852 100644
--- a/packages/block-library/src/group/editor.scss
+++ b/packages/block-library/src/group/editor.scss
@@ -39,9 +39,9 @@
 	&::after {
 		content: "";
 		display: flex;
-		flex: 1 0 $grid-unit-60;
+		flex: 1 0 $button-size-next-default-40px;
 		pointer-events: none;
-		min-height: $grid-unit-60 - $border-width - $border-width;
+		min-height: $button-size-next-default-40px - $border-width - $border-width;
 		border: $border-width dashed currentColor;
 	}