diff --git a/src/wp-includes/class-wp-theme-json.php b/src/wp-includes/class-wp-theme-json.php
index 30c24173f4b0b..b28cab868149d 100644
--- a/src/wp-includes/class-wp-theme-json.php
+++ b/src/wp-includes/class-wp-theme-json.php
@@ -262,6 +262,35 @@ class WP_Theme_JSON {
 		'box-shadow'                        => array( 'shadow' ),
 	);
 
+	/**
+	 * Indirect metadata for style properties that are not directly output.
+	 *
+	 * Each element maps from a CSS property name to an array of
+	 * paths to the value in theme.json & block attributes.
+	 *
+	 * Indirect properties are not output directly by `compute_style_properties`,
+	 * but are used elsewhere in the processing of global styles. The indirect
+	 * property is used to validate whether or not a style value is allowed.
+	 *
+	 * @since 6.1.2
+	 * @var array
+	 */
+	const INDIRECT_PROPERTIES_METADATA = array(
+		'gap'        => array(
+			array( 'spacing', 'blockGap' ),
+		),
+		'column-gap' => array(
+			array( 'spacing', 'blockGap', 'left' ),
+		),
+		'row-gap'    => array(
+			array( 'spacing', 'blockGap', 'top' ),
+		),
+		'max-width'  => array(
+			array( 'layout', 'contentSize' ),
+			array( 'layout', 'wideSize' ),
+		),
+	);
+
 	/**
 	 * Protected style properties.
 	 *
@@ -2949,6 +2978,10 @@ protected static function remove_insecure_settings( $input ) {
 				}
 			}
 		}
+
+		// Ensure indirect properties not included in any `PRESETS_METADATA` value are allowed.
+		static::remove_indirect_properties( $input, $output );
+
 		return $output;
 	}
 
@@ -2977,6 +3010,10 @@ protected static function remove_insecure_styles( $input ) {
 				}
 			}
 		}
+
+		// Ensure indirect properties not handled by `compute_style_properties` are allowed.
+		static::remove_indirect_properties( $input, $output );
+
 		return $output;
 	}
 
@@ -2995,6 +3032,29 @@ protected static function is_safe_css_declaration( $property_name, $property_val
 		return ! empty( trim( $filtered ) );
 	}
 
+	/**
+	 * Removes indirect properties from the given input node and
+	 * sets in the given output node.
+	 *
+	 * @since 6.1.2
+	 *
+	 * @param array $input  Node to process.
+	 * @param array $output The processed node. Passed by reference.
+	 */
+	private static function remove_indirect_properties( $input, &$output ) {
+		foreach ( static::INDIRECT_PROPERTIES_METADATA as $property => $paths ) {
+			foreach ( $paths as $path ) {
+				$value = _wp_array_get( $input, $path );
+				if (
+					is_string( $value ) &&
+					static::is_safe_css_declaration( $property, $value )
+				) {
+					_wp_array_set( $output, $path, $value );
+				}
+			}
+		}
+	}
+
 	/**
 	 * Returns the raw data.
 	 *
diff --git a/tests/phpunit/tests/theme/wpThemeJson.php b/tests/phpunit/tests/theme/wpThemeJson.php
index b2d05d9fe3d4a..26d410e322102 100644
--- a/tests/phpunit/tests/theme/wpThemeJson.php
+++ b/tests/phpunit/tests/theme/wpThemeJson.php
@@ -2426,6 +2426,67 @@ public function test_remove_insecure_properties_applies_safe_styles() {
 		$this->assertEqualSetsWithIndex( $expected, $actual );
 	}
 
+	/**
+	 * @ticket 57321
+	 *
+	 * @covers WP_Theme_JSON::remove_insecure_properties
+	 */
+	public function test_remove_insecure_properties_should_allow_indirect_properties() {
+		$actual = WP_Theme_JSON::remove_insecure_properties(
+			array(
+				'version'  => WP_Theme_JSON::LATEST_SCHEMA,
+				'styles'   => array(
+					'spacing' => array(
+						'blockGap' => '3em',
+					),
+					'blocks'  => array(
+						'core/social-links' => array(
+							'spacing' => array(
+								'blockGap' => array(
+									'left' => '2em',
+									'top'  => '1em',
+								),
+							),
+						),
+					),
+				),
+				'settings' => array(
+					'layout' => array(
+						'contentSize' => '800px',
+						'wideSize'    => '1000px',
+					),
+				),
+			)
+		);
+
+		$expected = array(
+			'version'  => WP_Theme_JSON::LATEST_SCHEMA,
+			'styles'   => array(
+				'spacing' => array(
+					'blockGap' => '3em',
+				),
+				'blocks'  => array(
+					'core/social-links' => array(
+						'spacing' => array(
+							'blockGap' => array(
+								'left' => '2em',
+								'top'  => '1em',
+							),
+						),
+					),
+				),
+			),
+			'settings' => array(
+				'layout' => array(
+					'contentSize' => '800px',
+					'wideSize'    => '1000px',
+				),
+			),
+		);
+
+		$this->assertSameSetsWithIndex( $expected, $actual );
+	}
+
 	/**
 	 * @ticket 56467
 	 */