diff --git a/Dockerfile b/Dockerfile
index 023fb2442946c..141e6e129d7b9 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -473,11 +473,14 @@ function common::get_packaging_tool() {
         echo
         export PACKAGING_TOOL="uv"
         export PACKAGING_TOOL_CMD="uv pip"
-        if [[ ${AIRFLOW_INSTALLATION_METHOD=} == "." && -f "./pyproject.toml" ]]; then
+        # --no-binary  is needed in order to avoid libxml and xmlsec using different version of libxml2
+         # (binary lxml embeds its own libxml2, while xmlsec uses system one).
+         # See https://bugs.launchpad.net/lxml/+bug/2110068
+         if [[ ${AIRFLOW_INSTALLATION_METHOD=} == "." && -f "./pyproject.toml" ]]; then
             # for uv only install dev group when we install from sources
-            export EXTRA_INSTALL_FLAGS="--group=dev"
+            export EXTRA_INSTALL_FLAGS="--group=dev --no-binary lxml --no-binary xmlsec"
         else
-            export EXTRA_INSTALL_FLAGS=""
+            export EXTRA_INSTALL_FLAGS="--no-binary lxml --no-binary xmlsec"
         fi
         export EXTRA_UNINSTALL_FLAGS=""
         export UPGRADE_TO_HIGHEST_RESOLUTION="--upgrade --resolution highest"
@@ -875,8 +878,12 @@ function install_from_sources() {
         echo
         echo "${COLOR_BLUE}Attempting to upgrade all packages to highest versions.${COLOR_RESET}"
         echo
+        # --no-binary  is needed in order to avoid libxml and xmlsec using different version of libxml2
+        # (binary lxml embeds its own libxml2, while xmlsec uses system one).
+        # See https://bugs.launchpad.net/lxml/+bug/2110068
         set -x
-        uv sync --all-packages --resolution highest --group dev --group docs --group docs-gen --group leveldb ${extra_sync_flags}
+        uv sync --all-packages --resolution highest --group dev --group docs --group docs-gen \
+            --group leveldb ${extra_sync_flags} --no-binary-package lxml --no-binary-package xmlsec
     else
         # We only use uv here but Installing using constraints is not supported with `uv sync`, so we
         # do not use ``uv sync`` because we are not committing and using uv.lock yet.
@@ -933,8 +940,12 @@ function install_from_sources() {
             echo
             echo "${COLOR_BLUE}Falling back to no-constraints installation.${COLOR_RESET}"
             echo
+            # --no-binary  is needed in order to avoid libxml and xmlsec using different version of libxml2
+            # (binary lxml embeds its own libxml2, while xmlsec uses system one).
+            # See https://bugs.launchpad.net/lxml/+bug/2110068
             set -x
-            uv sync --all-packages --group dev --group docs --group docs-gen --group leveldb ${extra_sync_flags}
+            uv sync --all-packages --group dev --group docs --group docs-gen \
+                --group leveldb ${extra_sync_flags} --no-binary-package lxml --no-binary-packag xmlsec
             set +x
         fi
     fi
diff --git a/Dockerfile.ci b/Dockerfile.ci
index 7fc0d572bf0c0..8168cc5187cf8 100644
--- a/Dockerfile.ci
+++ b/Dockerfile.ci
@@ -412,11 +412,14 @@ function common::get_packaging_tool() {
         echo
         export PACKAGING_TOOL="uv"
         export PACKAGING_TOOL_CMD="uv pip"
-        if [[ ${AIRFLOW_INSTALLATION_METHOD=} == "." && -f "./pyproject.toml" ]]; then
+        # --no-binary  is needed in order to avoid libxml and xmlsec using different version of libxml2
+         # (binary lxml embeds its own libxml2, while xmlsec uses system one).
+         # See https://bugs.launchpad.net/lxml/+bug/2110068
+         if [[ ${AIRFLOW_INSTALLATION_METHOD=} == "." && -f "./pyproject.toml" ]]; then
             # for uv only install dev group when we install from sources
-            export EXTRA_INSTALL_FLAGS="--group=dev"
+            export EXTRA_INSTALL_FLAGS="--group=dev --no-binary lxml --no-binary xmlsec"
         else
-            export EXTRA_INSTALL_FLAGS=""
+            export EXTRA_INSTALL_FLAGS="--no-binary lxml --no-binary xmlsec"
         fi
         export EXTRA_UNINSTALL_FLAGS=""
         export UPGRADE_TO_HIGHEST_RESOLUTION="--upgrade --resolution highest"
@@ -628,8 +631,12 @@ function install_from_sources() {
         echo
         echo "${COLOR_BLUE}Attempting to upgrade all packages to highest versions.${COLOR_RESET}"
         echo
+        # --no-binary  is needed in order to avoid libxml and xmlsec using different version of libxml2
+        # (binary lxml embeds its own libxml2, while xmlsec uses system one).
+        # See https://bugs.launchpad.net/lxml/+bug/2110068
         set -x
-        uv sync --all-packages --resolution highest --group dev --group docs --group docs-gen --group leveldb ${extra_sync_flags}
+        uv sync --all-packages --resolution highest --group dev --group docs --group docs-gen \
+            --group leveldb ${extra_sync_flags} --no-binary-package lxml --no-binary-package xmlsec
     else
         # We only use uv here but Installing using constraints is not supported with `uv sync`, so we
         # do not use ``uv sync`` because we are not committing and using uv.lock yet.
@@ -686,8 +693,12 @@ function install_from_sources() {
             echo
             echo "${COLOR_BLUE}Falling back to no-constraints installation.${COLOR_RESET}"
             echo
+            # --no-binary  is needed in order to avoid libxml and xmlsec using different version of libxml2
+            # (binary lxml embeds its own libxml2, while xmlsec uses system one).
+            # See https://bugs.launchpad.net/lxml/+bug/2110068
             set -x
-            uv sync --all-packages --group dev --group docs --group docs-gen --group leveldb ${extra_sync_flags}
+            uv sync --all-packages --group dev --group docs --group docs-gen \
+                --group leveldb ${extra_sync_flags} --no-binary-package lxml --no-binary-packag xmlsec
             set +x
         fi
     fi
@@ -1125,13 +1136,19 @@ function check_force_lowest_dependencies() {
             exit 0
         fi
         cd "${AIRFLOW_SOURCES}/providers/${provider_id/.//}" || exit 1
-        uv sync --resolution lowest-direct
+        # --no-binary  is needed in order to avoid libxml and xmlsec using different version of libxml2
+        # (binary lxml embeds its own libxml2, while xmlsec uses system one).
+        # See https://bugs.launchpad.net/lxml/+bug/2110068
+        uv sync --resolution lowest-direct --no-binary-package lxml --no-binary-package xmlsec
     else
         echo
         echo "${COLOR_BLUE}Forcing dependencies to lowest versions for Airflow.${COLOR_RESET}"
         echo
         cd "${AIRFLOW_SOURCES}/airflow-core"
-        uv sync --resolution lowest-direct
+        # --no-binary  is needed in order to avoid libxml and xmlsec using different version of libxml2
+        # (binary lxml embeds its own libxml2, while xmlsec uses system one).
+        # See https://bugs.launchpad.net/lxml/+bug/2110068
+        uv sync --resolution lowest-direct --no-binary-package lxml --no-binary-package xmlsec
     fi
 }
 
diff --git a/scripts/docker/common.sh b/scripts/docker/common.sh
index 4568aa2183b14..259ac7a76ec2e 100644
--- a/scripts/docker/common.sh
+++ b/scripts/docker/common.sh
@@ -42,11 +42,14 @@ function common::get_packaging_tool() {
         echo
         export PACKAGING_TOOL="uv"
         export PACKAGING_TOOL_CMD="uv pip"
-        if [[ ${AIRFLOW_INSTALLATION_METHOD=} == "." && -f "./pyproject.toml" ]]; then
+        # --no-binary  is needed in order to avoid libxml and xmlsec using different version of libxml2
+         # (binary lxml embeds its own libxml2, while xmlsec uses system one).
+         # See https://bugs.launchpad.net/lxml/+bug/2110068
+         if [[ ${AIRFLOW_INSTALLATION_METHOD=} == "." && -f "./pyproject.toml" ]]; then
             # for uv only install dev group when we install from sources
-            export EXTRA_INSTALL_FLAGS="--group=dev"
+            export EXTRA_INSTALL_FLAGS="--group=dev --no-binary lxml --no-binary xmlsec"
         else
-            export EXTRA_INSTALL_FLAGS=""
+            export EXTRA_INSTALL_FLAGS="--no-binary lxml --no-binary xmlsec"
         fi
         export EXTRA_UNINSTALL_FLAGS=""
         export UPGRADE_TO_HIGHEST_RESOLUTION="--upgrade --resolution highest"
diff --git a/scripts/docker/entrypoint_ci.sh b/scripts/docker/entrypoint_ci.sh
index e62e0a58c8002..b8a4e994ceb21 100755
--- a/scripts/docker/entrypoint_ci.sh
+++ b/scripts/docker/entrypoint_ci.sh
@@ -336,13 +336,19 @@ function check_force_lowest_dependencies() {
             exit 0
         fi
         cd "${AIRFLOW_SOURCES}/providers/${provider_id/.//}" || exit 1
-        uv sync --resolution lowest-direct
+        # --no-binary  is needed in order to avoid libxml and xmlsec using different version of libxml2
+        # (binary lxml embeds its own libxml2, while xmlsec uses system one).
+        # See https://bugs.launchpad.net/lxml/+bug/2110068
+        uv sync --resolution lowest-direct --no-binary-package lxml --no-binary-package xmlsec
     else
         echo
         echo "${COLOR_BLUE}Forcing dependencies to lowest versions for Airflow.${COLOR_RESET}"
         echo
         cd "${AIRFLOW_SOURCES}/airflow-core"
-        uv sync --resolution lowest-direct
+        # --no-binary  is needed in order to avoid libxml and xmlsec using different version of libxml2
+        # (binary lxml embeds its own libxml2, while xmlsec uses system one).
+        # See https://bugs.launchpad.net/lxml/+bug/2110068
+        uv sync --resolution lowest-direct --no-binary-package lxml --no-binary-package xmlsec
     fi
 }
 
diff --git a/scripts/docker/install_airflow_when_building_images.sh b/scripts/docker/install_airflow_when_building_images.sh
index 3291a6b4cc0b4..78ddc7eaf8589 100644
--- a/scripts/docker/install_airflow_when_building_images.sh
+++ b/scripts/docker/install_airflow_when_building_images.sh
@@ -56,8 +56,12 @@ function install_from_sources() {
         echo
         echo "${COLOR_BLUE}Attempting to upgrade all packages to highest versions.${COLOR_RESET}"
         echo
+        # --no-binary  is needed in order to avoid libxml and xmlsec using different version of libxml2
+        # (binary lxml embeds its own libxml2, while xmlsec uses system one).
+        # See https://bugs.launchpad.net/lxml/+bug/2110068
         set -x
-        uv sync --all-packages --resolution highest --group dev --group docs --group docs-gen --group leveldb ${extra_sync_flags}
+        uv sync --all-packages --resolution highest --group dev --group docs --group docs-gen \
+            --group leveldb ${extra_sync_flags} --no-binary-package lxml --no-binary-package xmlsec
     else
         # We only use uv here but Installing using constraints is not supported with `uv sync`, so we
         # do not use ``uv sync`` because we are not committing and using uv.lock yet.
@@ -114,8 +118,12 @@ function install_from_sources() {
             echo
             echo "${COLOR_BLUE}Falling back to no-constraints installation.${COLOR_RESET}"
             echo
+            # --no-binary  is needed in order to avoid libxml and xmlsec using different version of libxml2
+            # (binary lxml embeds its own libxml2, while xmlsec uses system one).
+            # See https://bugs.launchpad.net/lxml/+bug/2110068
             set -x
-            uv sync --all-packages --group dev --group docs --group docs-gen --group leveldb ${extra_sync_flags}
+            uv sync --all-packages --group dev --group docs --group docs-gen \
+                --group leveldb ${extra_sync_flags} --no-binary-package lxml --no-binary-packag xmlsec
             set +x
         fi
     fi