diff --git a/src/wp-includes/class-wp-theme-json.php b/src/wp-includes/class-wp-theme-json.php
index acff2963802c7..bf741637c318e 100644
--- a/src/wp-includes/class-wp-theme-json.php
+++ b/src/wp-includes/class-wp-theme-json.php
@@ -931,6 +931,27 @@ public function get_settings() {
 		}
 	}
 
+	/**
+	 * Processes the CSS, to apply nesting.
+	 *
+	 * @param string $css      The CSS to process.
+	 * @param string $selector The selector to nest.
+	 *
+	 * @return string The processed CSS.
+	 */
+	public function process_blocks_custom_css( $css, $selector ) {
+		$processed_css = '';
+
+		// Split CSS nested rules.
+		$parts = explode( '&', $css );
+		foreach ( $parts as $part ) {
+			$processed_css .= ( ! str_contains( $part, '{' ) )
+				? trim( $selector ) . '{' . trim( $part ) . '}' // If the part doesn't contain braces, it applies to the root level.
+				: trim( $selector . $part ); // Prepend the selector, which effectively replaces the "&" character.
+		}
+		return $processed_css;
+	}
+
 	/**
 	 * Returns the stylesheet that results of processing
 	 * the theme.json structure this object represents.
@@ -1005,7 +1026,19 @@ public function get_stylesheet( $types = array( 'variables', 'styles', 'presets'
 
 		// Load the custom CSS last so it has the highest specificity.
 		if ( in_array( 'custom-css', $types, true ) ) {
+			// Add the global styles root CSS.
 			$stylesheet .= _wp_array_get( $this->theme_json, array( 'styles', 'css' ) );
+
+			// Add the global styles block CSS.
+			if ( isset( $this->theme_json['styles']['blocks'] ) ) {
+				foreach ( $this->theme_json['styles']['blocks'] as $name => $node ) {
+					$custom_block_css = _wp_array_get( $this->theme_json, array( 'styles', 'blocks', $name, 'css' ) );
+					if ( $custom_block_css ) {
+						$selector    = static::$blocks_metadata[ $name ]['selector'];
+						$stylesheet .= $this->process_blocks_custom_css( $custom_block_css, $selector );
+					}
+				}
+			}
 		}
 
 		return $stylesheet;
diff --git a/tests/phpunit/tests/theme/wpThemeJson.php b/tests/phpunit/tests/theme/wpThemeJson.php
index 54645bc1dee6b..39dadf3d020e1 100644
--- a/tests/phpunit/tests/theme/wpThemeJson.php
+++ b/tests/phpunit/tests/theme/wpThemeJson.php
@@ -4698,4 +4698,55 @@ public function data_custom_css_for_user_caps() {
 			),
 		);
 	}
+
+	/**
+	 * @dataProvider data_process_blocks_custom_css
+	 *
+	 * @param array  $input    An array containing the selector and css to test.
+	 * @param string $expected Expected results.
+	 */
+	public function test_process_blocks_custom_css( $input, $expected ) {
+		$theme_json = new WP_Theme_JSON(
+			array(
+				'version' => WP_Theme_JSON::LATEST_SCHEMA,
+				'styles'  => array(),
+			)
+		);
+
+		$this->assertEquals( $expected, $theme_json->process_blocks_custom_css( $input['css'], $input['selector'] ) );
+	}
+
+	/**
+	 * Data provider.
+	 *
+	 * @return array[]
+	 */
+	public function data_process_blocks_custom_css() {
+		return array(
+			// Simple CSS without any child selectors.
+			'no child selectors'                => array(
+				'input'    => array(
+					'selector' => '.foo',
+					'css'      => 'color: red; margin: auto;',
+				),
+				'expected' => '.foo{color: red; margin: auto;}',
+			),
+			// CSS with child selectors.
+			'with children'                     => array(
+				'input'    => array(
+					'selector' => '.foo',
+					'css'      => 'color: red; margin: auto; & .bar{color: blue;}',
+				),
+				'expected' => '.foo{color: red; margin: auto;}.foo .bar{color: blue;}',
+			),
+			// CSS with child selectors and pseudo elements.
+			'with children and pseudo elements' => array(
+				'input'    => array(
+					'selector' => '.foo',
+					'css'      => 'color: red; margin: auto; & .bar{color: blue;} &::before{color: green;}',
+				),
+				'expected' => '.foo{color: red; margin: auto;}.foo .bar{color: blue;}.foo::before{color: green;}',
+			),
+		);
+	}
 }