diff --git a/crates/uv-cli/src/lib.rs b/crates/uv-cli/src/lib.rs
index ede53be980c2..7856a14c7a65 100644
--- a/crates/uv-cli/src/lib.rs
+++ b/crates/uv-cli/src/lib.rs
@@ -1236,8 +1236,8 @@ pub struct PipSyncArgs {
 }
 
 #[derive(Args)]
-#[allow(clippy::struct_excessive_bools)]
 #[command(group = clap::ArgGroup::new("sources").required(true).multiple(true))]
+#[allow(clippy::struct_excessive_bools)]
 pub struct PipInstallArgs {
     /// Install all listed packages.
     #[arg(group = "sources")]
@@ -1517,8 +1517,8 @@ pub struct PipInstallArgs {
 }
 
 #[derive(Args)]
-#[allow(clippy::struct_excessive_bools)]
 #[command(group = clap::ArgGroup::new("sources").required(true).multiple(true))]
+#[allow(clippy::struct_excessive_bools)]
 pub struct PipUninstallArgs {
     /// Uninstall all listed packages.
     #[arg(group = "sources")]
@@ -2358,11 +2358,18 @@ pub struct LockArgs {
 }
 
 #[derive(Args)]
+#[command(group = clap::ArgGroup::new("sources").required(true).multiple(true))]
 #[allow(clippy::struct_excessive_bools)]
 pub struct AddArgs {
     /// The packages to add, as PEP 508 requirements (e.g., `ruff==0.5.0`).
-    #[arg(required = true)]
-    pub requirements: Vec<String>,
+    #[arg(group = "sources")]
+    pub packages: Vec<String>,
+
+    /// Add all packages listed in the given `requirements.txt` files.
+    ///
+    /// Implies `--raw-sources`.
+    #[arg(long, short, group = "sources", value_parser = parse_file_path)]
+    pub requirements: Vec<PathBuf>,
 
     /// Add the requirements as development dependencies.
     #[arg(long, conflicts_with("optional"))]
diff --git a/crates/uv/src/commands/project/add.rs b/crates/uv/src/commands/project/add.rs
index 3a35c685a83e..483b3cc9402c 100644
--- a/crates/uv/src/commands/project/add.rs
+++ b/crates/uv/src/commands/project/add.rs
@@ -1,7 +1,7 @@
 use std::collections::hash_map::Entry;
-use std::path::PathBuf;
+use std::path::{Path, PathBuf};
 
-use anyhow::{Context, Result};
+use anyhow::{bail, Context, Result};
 use cache_key::RepositoryUrl;
 use owo_colors::OwoColorize;
 use pep508_rs::{ExtraName, Requirement, VersionOrUrl};
@@ -71,6 +71,26 @@ pub(crate) async fn add(
         warn_user_once!("`uv add` is experimental and may change without warning");
     }
 
+    for source in &requirements {
+        match source {
+            RequirementsSource::PyprojectToml(_) => {
+                bail!("Adding requirements from a `pyproject.toml` is not supported in `uv add`");
+            }
+            RequirementsSource::SetupPy(_) => {
+                bail!("Adding requirements from a `setup.py` is not supported in `uv add`");
+            }
+            RequirementsSource::SetupCfg(_) => {
+                bail!("Adding requirements from a `setup.cfg` is not supported in `uv add`");
+            }
+            RequirementsSource::RequirementsTxt(path) => {
+                if path == Path::new("-") {
+                    bail!("Reading requirements from stdin is not supported in `uv add`");
+                }
+            }
+            _ => {}
+        }
+    }
+
     let reporter = PythonDownloadReporter::single(printer);
 
     let target = if let Some(script) = script {
diff --git a/crates/uv/src/lib.rs b/crates/uv/src/lib.rs
index 8d05c177e0a7..42bebb8ad24f 100644
--- a/crates/uv/src/lib.rs
+++ b/crates/uv/src/lib.rs
@@ -1147,14 +1147,35 @@ async fn run_project(
                     .combine(Refresh::from(args.settings.upgrade.clone())),
             );
 
+            // Use raw sources if requirements files are provided as input.
+            let raw_sources = if args.requirements.is_empty() {
+                args.raw_sources
+            } else {
+                if args.raw_sources {
+                    warn_user!("`--raw-sources` is a no-op for `requirements.txt` files, which are always treated as raw sources");
+                }
+                true
+            };
+
+            let requirements = args
+                .packages
+                .into_iter()
+                .map(RequirementsSource::Package)
+                .chain(
+                    args.requirements
+                        .into_iter()
+                        .map(RequirementsSource::from_requirements_file),
+                )
+                .collect::<Vec<_>>();
+
             commands::add(
                 args.locked,
                 args.frozen,
                 args.no_sync,
-                args.requirements,
+                requirements,
                 args.editable,
                 args.dependency_type,
-                args.raw_sources,
+                raw_sources,
                 args.rev,
                 args.tag,
                 args.branch,
diff --git a/crates/uv/src/settings.rs b/crates/uv/src/settings.rs
index 7124da598228..0f290a47b73b 100644
--- a/crates/uv/src/settings.rs
+++ b/crates/uv/src/settings.rs
@@ -28,7 +28,6 @@ use uv_configuration::{
 };
 use uv_normalize::PackageName;
 use uv_python::{Prefix, PythonDownloads, PythonPreference, PythonVersion, Target};
-use uv_requirements::RequirementsSource;
 use uv_resolver::{AnnotationStyle, DependencyMode, ExcludeNewer, PrereleaseMode, ResolutionMode};
 use uv_settings::{
     Combine, FilesystemOptions, Options, PipOptions, ResolverInstallerOptions, ResolverOptions,
@@ -694,7 +693,8 @@ pub(crate) struct AddSettings {
     pub(crate) locked: bool,
     pub(crate) frozen: bool,
     pub(crate) no_sync: bool,
-    pub(crate) requirements: Vec<RequirementsSource>,
+    pub(crate) packages: Vec<String>,
+    pub(crate) requirements: Vec<PathBuf>,
     pub(crate) dependency_type: DependencyType,
     pub(crate) editable: Option<bool>,
     pub(crate) extras: Vec<ExtraName>,
@@ -714,6 +714,7 @@ impl AddSettings {
     #[allow(clippy::needless_pass_by_value)]
     pub(crate) fn resolve(args: AddArgs, filesystem: Option<FilesystemOptions>) -> Self {
         let AddArgs {
+            packages,
             requirements,
             dev,
             optional,
@@ -735,11 +736,6 @@ impl AddSettings {
             python,
         } = args;
 
-        let requirements = requirements
-            .into_iter()
-            .map(RequirementsSource::Package)
-            .collect::<Vec<_>>();
-
         let dependency_type = if let Some(group) = optional {
             DependencyType::Optional(group)
         } else if dev {
@@ -752,6 +748,7 @@ impl AddSettings {
             locked,
             frozen,
             no_sync,
+            packages,
             requirements,
             dependency_type,
             raw_sources,
diff --git a/crates/uv/tests/edit.rs b/crates/uv/tests/edit.rs
index f969e1d9c1d4..7b138f4e4d96 100644
--- a/crates/uv/tests/edit.rs
+++ b/crates/uv/tests/edit.rs
@@ -794,7 +794,7 @@ fn add_raw_error() -> Result<()> {
     ----- stderr -----
     error: the argument '--tag <TAG>' cannot be used with '--raw-sources'
 
-    Usage: uv add --cache-dir [CACHE_DIR] --tag <TAG> --exclude-newer <EXCLUDE_NEWER> <REQUIREMENTS>...
+    Usage: uv add --cache-dir [CACHE_DIR] --tag <TAG> --exclude-newer <EXCLUDE_NEWER> <PACKAGES|--requirements <REQUIREMENTS>>
 
     For more information, try '--help'.
     "###);
@@ -2732,7 +2732,7 @@ fn add_reject_multiple_git_ref_flags() {
     ----- stderr -----
     error: the argument '--tag <TAG>' cannot be used with '--branch <BRANCH>'
 
-    Usage: uv add --cache-dir [CACHE_DIR] --tag <TAG> --exclude-newer <EXCLUDE_NEWER> <REQUIREMENTS>...
+    Usage: uv add --cache-dir [CACHE_DIR] --tag <TAG> --exclude-newer <EXCLUDE_NEWER> <PACKAGES|--requirements <REQUIREMENTS>>
 
     For more information, try '--help'.
     "###
@@ -2753,7 +2753,7 @@ fn add_reject_multiple_git_ref_flags() {
     ----- stderr -----
     error: the argument '--tag <TAG>' cannot be used with '--rev <REV>'
 
-    Usage: uv add --cache-dir [CACHE_DIR] --tag <TAG> --exclude-newer <EXCLUDE_NEWER> <REQUIREMENTS>...
+    Usage: uv add --cache-dir [CACHE_DIR] --tag <TAG> --exclude-newer <EXCLUDE_NEWER> <PACKAGES|--requirements <REQUIREMENTS>>
 
     For more information, try '--help'.
     "###
@@ -2774,7 +2774,7 @@ fn add_reject_multiple_git_ref_flags() {
     ----- stderr -----
     error: the argument '--tag <TAG>' cannot be used multiple times
 
-    Usage: uv add [OPTIONS] <REQUIREMENTS>...
+    Usage: uv add [OPTIONS] <PACKAGES|--requirements <REQUIREMENTS>>
 
     For more information, try '--help'.
     "###
@@ -3410,6 +3410,109 @@ fn add_repeat() -> Result<()> {
     Ok(())
 }
 
+/// Add from requirement file.
+#[test]
+fn add_requirements_file() -> Result<()> {
+    let context = TestContext::new("3.12").with_filtered_counts();
+
+    let pyproject_toml = context.temp_dir.child("pyproject.toml");
+    pyproject_toml.write_str(indoc! {r#"
+        [project]
+        name = "project"
+        version = "0.1.0"
+        # ...
+        requires-python = ">=3.12"
+        dependencies = []
+    "#})?;
+
+    let requirements_txt = context.temp_dir.child("requirements.txt");
+    requirements_txt.write_str("Flask==2.3.2\ngit+https://github.com/agronholm/anyio.git@4.4.0")?;
+
+    uv_snapshot!(context.filters(), context.add(&[]).arg("-r").arg("requirements.txt"), @r###"
+    success: true
+    exit_code: 0
+    ----- stdout -----
+
+    ----- stderr -----
+    warning: `uv add` is experimental and may change without warning
+    Resolved [N] packages in [TIME]
+    Prepared [N] packages in [TIME]
+    Installed [N] packages in [TIME]
+     + anyio==4.4.0 (from git+https://github.com/agronholm/anyio.git@053e8f0a0f7b0f4a47a012eb5c6b1d9d84344e6a)
+     + blinker==1.7.0
+     + click==8.1.7
+     + flask==2.3.2
+     + idna==3.6
+     + itsdangerous==2.1.2
+     + jinja2==3.1.3
+     + markupsafe==2.1.5
+     + project==0.1.0 (from file://[TEMP_DIR]/)
+     + sniffio==1.3.1
+     + werkzeug==3.0.1
+    "###);
+
+    let pyproject_toml = fs_err::read_to_string(context.temp_dir.join("pyproject.toml"))?;
+
+    insta::with_settings!({
+        filters => context.filters(),
+    }, {
+        assert_snapshot!(
+            pyproject_toml, @r###"
+        [project]
+        name = "project"
+        version = "0.1.0"
+        # ...
+        requires-python = ">=3.12"
+        dependencies = [
+            "flask==2.3.2",
+            "anyio @ git+https://github.com/agronholm/anyio.git@4.4.0",
+        ]
+        "###
+        );
+    });
+
+    // Using `--raw-sources` with `-r` should warn.
+    uv_snapshot!(context.filters(), context.add(&[]).arg("-r").arg("requirements.txt").arg("--raw-sources"), @r###"
+    success: true
+    exit_code: 0
+    ----- stdout -----
+
+    ----- stderr -----
+    warning: `--raw-sources` is a no-op for `requirements.txt` files, which are always treated as raw sources
+    warning: `uv add` is experimental and may change without warning
+    Resolved [N] packages in [TIME]
+    Audited [N] packages in [TIME]
+    "###);
+
+    // Passing a `setup.py` should fail.
+    uv_snapshot!(context.filters(), context.add(&[]).arg("-r").arg("setup.py"), @r###"
+    success: false
+    exit_code: 2
+    ----- stdout -----
+
+    ----- stderr -----
+    warning: `uv add` is experimental and may change without warning
+    error: Adding requirements from a `setup.py` is not supported in `uv add`
+    "###);
+
+    // Passing nothing should fail.
+    uv_snapshot!(context.filters(), context.add(&[]), @r###"
+    success: false
+    exit_code: 2
+    ----- stdout -----
+
+    ----- stderr -----
+    error: the following required arguments were not provided:
+      <PACKAGES|--requirements <REQUIREMENTS>>
+
+    Usage: uv add --cache-dir [CACHE_DIR] --exclude-newer <EXCLUDE_NEWER> <PACKAGES|--requirements <REQUIREMENTS>>
+
+    For more information, try '--help'.
+    "###);
+
+    Ok(())
+}
+
 /// Add to a PEP 732 script.
 #[test]
 fn add_script() -> Result<()> {
diff --git a/docs/reference/cli.md b/docs/reference/cli.md
index 90cf40aae2fb..75133695b40a 100644
--- a/docs/reference/cli.md
+++ b/docs/reference/cli.md
@@ -466,12 +466,12 @@ uv will search for a project in the current directory or any parent directory. I
 <h3 class="cli-reference">Usage</h3>
 
 ```
-uv add [OPTIONS] <REQUIREMENTS>...
+uv add [OPTIONS] <PACKAGES|--requirements <REQUIREMENTS>>
 ```
 
 <h3 class="cli-reference">Arguments</h3>
 
-<dl class="cli-reference"><dt><code>REQUIREMENTS</code></dt><dd><p>The packages to add, as PEP 508 requirements (e.g., <code>ruff==0.5.0</code>)</p>
+<dl class="cli-reference"><dt><code>PACKAGES</code></dt><dd><p>The packages to add, as PEP 508 requirements (e.g., <code>ruff==0.5.0</code>)</p>
 
 </dd></dl>
 
@@ -696,6 +696,10 @@ uv add [OPTIONS] <REQUIREMENTS>...
 
 </dd><dt><code>--reinstall-package</code> <i>reinstall-package</i></dt><dd><p>Reinstall a specific package, regardless of whether it&#8217;s already installed. Implies <code>--refresh-package</code></p>
 
+</dd><dt><code>--requirements</code>, <code>-r</code> <i>requirements</i></dt><dd><p>Add all packages listed in the given <code>requirements.txt</code> files.</p>
+
+<p>Implies <code>--raw-sources</code>.</p>
+
 </dd><dt><code>--resolution</code> <i>resolution</i></dt><dd><p>The strategy to use when selecting between the different compatible versions for a given package requirement.</p>
 
 <p>By default, uv will use the latest compatible version of each package (<code>highest</code>).</p>