diff --git a/clients/client-omics/src/commands/GetReadSetMetadataCommand.ts b/clients/client-omics/src/commands/GetReadSetMetadataCommand.ts
index 00784f5f020a..373c933152de 100644
--- a/clients/client-omics/src/commands/GetReadSetMetadataCommand.ts
+++ b/clients/client-omics/src/commands/GetReadSetMetadataCommand.ts
@@ -85,6 +85,7 @@ export interface GetReadSetMetadataCommandOutput extends GetReadSetMetadataRespo
  * //     },
  * //   },
  * //   statusMessage: "STRING_VALUE",
+ * //   creationType: "STRING_VALUE",
  * // };
  *
  * ```
diff --git a/clients/client-omics/src/commands/ListReadSetsCommand.ts b/clients/client-omics/src/commands/ListReadSetsCommand.ts
index d9bd21e2b1d7..d3f09b0175d3 100644
--- a/clients/client-omics/src/commands/ListReadSetsCommand.ts
+++ b/clients/client-omics/src/commands/ListReadSetsCommand.ts
@@ -56,6 +56,7 @@ export interface ListReadSetsCommandOutput extends ListReadSetsResponse, __Metad
  *     sampleId: "STRING_VALUE",
  *     subjectId: "STRING_VALUE",
  *     generatedFrom: "STRING_VALUE",
+ *     creationType: "STRING_VALUE",
  *   },
  * };
  * const command = new ListReadSetsCommand(input);
@@ -82,6 +83,7 @@ export interface ListReadSetsCommandOutput extends ListReadSetsResponse, __Metad
  * //       },
  * //       creationTime: new Date("TIMESTAMP"), // required
  * //       statusMessage: "STRING_VALUE",
+ * //       creationType: "STRING_VALUE",
  * //     },
  * //   ],
  * // };
diff --git a/clients/client-omics/src/models/models_0.ts b/clients/client-omics/src/models/models_0.ts
index 4327f42fbea7..00062da150fa 100644
--- a/clients/client-omics/src/models/models_0.ts
+++ b/clients/client-omics/src/models/models_0.ts
@@ -2144,6 +2144,20 @@ export interface CreateWorkflowResponse {
   tags?: Record<string, string>;
 }
 
+/**
+ * @public
+ * @enum
+ */
+export const CreationType = {
+  IMPORT: "IMPORT",
+  UPLOAD: "UPLOAD",
+} as const;
+
+/**
+ * @public
+ */
+export type CreationType = (typeof CreationType)[keyof typeof CreationType];
+
 /**
  * @public
  */
@@ -2908,6 +2922,13 @@ export interface GetReadSetMetadataResponse {
    *     </p>
    */
   statusMessage?: string;
+
+  /**
+   * <p>
+   *       The creation type of the read set.
+   *     </p>
+   */
+  creationType?: CreationType | string;
 }
 
 /**
@@ -4365,6 +4386,13 @@ export interface ReadSetFilter {
    *     </p>
    */
   generatedFrom?: string;
+
+  /**
+   * <p>
+   *       The creation type of the read set.
+   *     </p>
+   */
+  creationType?: CreationType | string;
 }
 
 /**
@@ -4463,6 +4491,13 @@ export interface ReadSetListItem {
    *     </p>
    */
   statusMessage?: string;
+
+  /**
+   * <p>
+   *       The creation type of the read set.
+   *     </p>
+   */
+  creationType?: CreationType | string;
 }
 
 /**
diff --git a/clients/client-omics/src/protocols/Aws_restJson1.ts b/clients/client-omics/src/protocols/Aws_restJson1.ts
index 7dc724464795..3da33921bdbb 100644
--- a/clients/client-omics/src/protocols/Aws_restJson1.ts
+++ b/clients/client-omics/src/protocols/Aws_restJson1.ts
@@ -4916,6 +4916,7 @@ export const de_GetReadSetMetadataCommand = async (
   const doc = take(data, {
     arn: __expectString,
     creationTime: (_) => __expectNonNull(__parseRfc3339DateTimeWithOffset(_)),
+    creationType: __expectString,
     description: __expectString,
     fileType: __expectString,
     files: _json,
@@ -8196,6 +8197,7 @@ const se_ReadSetFilter = (input: ReadSetFilter, context: __SerdeContext): any =>
   return take(input, {
     createdAfter: (_) => _.toISOString().split(".")[0] + "Z",
     createdBefore: (_) => _.toISOString().split(".")[0] + "Z",
+    creationType: [],
     generatedFrom: [],
     name: [],
     referenceArn: [],
@@ -8548,6 +8550,7 @@ const de_ReadSetListItem = (output: any, context: __SerdeContext): ReadSetListIt
   return take(output, {
     arn: __expectString,
     creationTime: (_: any) => __expectNonNull(__parseRfc3339DateTimeWithOffset(_)),
+    creationType: __expectString,
     description: __expectString,
     fileType: __expectString,
     id: __expectString,
diff --git a/codegen/sdk-codegen/aws-models/omics.json b/codegen/sdk-codegen/aws-models/omics.json
index 6b1f23ed37de..8b2911d6de47 100644
--- a/codegen/sdk-codegen/aws-models/omics.json
+++ b/codegen/sdk-codegen/aws-models/omics.json
@@ -2058,6 +2058,21 @@
         "smithy.api#timestampFormat": "date-time"
       }
     },
+    "com.amazonaws.omics#CreationType": {
+      "type": "string",
+      "traits": {
+        "smithy.api#enum": [
+          {
+            "value": "IMPORT",
+            "name": "IMPORT"
+          },
+          {
+            "value": "UPLOAD",
+            "name": "UPLOAD"
+          }
+        ]
+      }
+    },
     "com.amazonaws.omics#DeleteAnnotationStore": {
       "type": "operation",
       "input": {
@@ -4195,6 +4210,12 @@
           "traits": {
             "smithy.api#documentation": "<p>\n      The status message for a read set. It provides more detail as to why the read set has a status. \n    </p>"
           }
+        },
+        "creationType": {
+          "target": "com.amazonaws.omics#CreationType",
+          "traits": {
+            "smithy.api#documentation": "<p>\n      The creation type of the read set.\n    </p>"
+          }
         }
       },
       "traits": {
@@ -9429,55 +9450,55 @@
         "smithy.rules#endpointTests": {
           "testCases": [
             {
-              "documentation": "For region us-gov-east-1 with FIPS enabled and DualStack enabled",
+              "documentation": "For region us-east-1 with FIPS enabled and DualStack enabled",
               "expect": {
                 "endpoint": {
-                  "url": "https://omics-fips.us-gov-east-1.api.aws"
+                  "url": "https://omics-fips.us-east-1.api.aws"
                 }
               },
               "params": {
-                "UseDualStack": true,
-                "Region": "us-gov-east-1",
-                "UseFIPS": true
+                "Region": "us-east-1",
+                "UseFIPS": true,
+                "UseDualStack": true
               }
             },
             {
-              "documentation": "For region us-gov-east-1 with FIPS enabled and DualStack disabled",
+              "documentation": "For region us-east-1 with FIPS enabled and DualStack disabled",
               "expect": {
                 "endpoint": {
-                  "url": "https://omics-fips.us-gov-east-1.amazonaws.com"
+                  "url": "https://omics-fips.us-east-1.amazonaws.com"
                 }
               },
               "params": {
-                "UseDualStack": false,
-                "Region": "us-gov-east-1",
-                "UseFIPS": true
+                "Region": "us-east-1",
+                "UseFIPS": true,
+                "UseDualStack": false
               }
             },
             {
-              "documentation": "For region us-gov-east-1 with FIPS disabled and DualStack enabled",
+              "documentation": "For region us-east-1 with FIPS disabled and DualStack enabled",
               "expect": {
                 "endpoint": {
-                  "url": "https://omics.us-gov-east-1.api.aws"
+                  "url": "https://omics.us-east-1.api.aws"
                 }
               },
               "params": {
-                "UseDualStack": true,
-                "Region": "us-gov-east-1",
-                "UseFIPS": false
+                "Region": "us-east-1",
+                "UseFIPS": false,
+                "UseDualStack": true
               }
             },
             {
-              "documentation": "For region us-gov-east-1 with FIPS disabled and DualStack disabled",
+              "documentation": "For region us-east-1 with FIPS disabled and DualStack disabled",
               "expect": {
                 "endpoint": {
-                  "url": "https://omics.us-gov-east-1.amazonaws.com"
+                  "url": "https://omics.us-east-1.amazonaws.com"
                 }
               },
               "params": {
-                "UseDualStack": false,
-                "Region": "us-gov-east-1",
-                "UseFIPS": false
+                "Region": "us-east-1",
+                "UseFIPS": false,
+                "UseDualStack": false
               }
             },
             {
@@ -9488,9 +9509,9 @@
                 }
               },
               "params": {
-                "UseDualStack": true,
                 "Region": "cn-north-1",
-                "UseFIPS": true
+                "UseFIPS": true,
+                "UseDualStack": true
               }
             },
             {
@@ -9501,9 +9522,9 @@
                 }
               },
               "params": {
-                "UseDualStack": false,
                 "Region": "cn-north-1",
-                "UseFIPS": true
+                "UseFIPS": true,
+                "UseDualStack": false
               }
             },
             {
@@ -9514,9 +9535,9 @@
                 }
               },
               "params": {
-                "UseDualStack": true,
                 "Region": "cn-north-1",
-                "UseFIPS": false
+                "UseFIPS": false,
+                "UseDualStack": true
               }
             },
             {
@@ -9527,109 +9548,109 @@
                 }
               },
               "params": {
-                "UseDualStack": false,
                 "Region": "cn-north-1",
-                "UseFIPS": false
+                "UseFIPS": false,
+                "UseDualStack": false
               }
             },
             {
-              "documentation": "For region us-iso-east-1 with FIPS enabled and DualStack enabled",
+              "documentation": "For region us-gov-east-1 with FIPS enabled and DualStack enabled",
               "expect": {
-                "error": "FIPS and DualStack are enabled, but this partition does not support one or both"
+                "endpoint": {
+                  "url": "https://omics-fips.us-gov-east-1.api.aws"
+                }
               },
               "params": {
-                "UseDualStack": true,
-                "Region": "us-iso-east-1",
-                "UseFIPS": true
+                "Region": "us-gov-east-1",
+                "UseFIPS": true,
+                "UseDualStack": true
               }
             },
             {
-              "documentation": "For region us-iso-east-1 with FIPS enabled and DualStack disabled",
+              "documentation": "For region us-gov-east-1 with FIPS enabled and DualStack disabled",
               "expect": {
                 "endpoint": {
-                  "url": "https://omics-fips.us-iso-east-1.c2s.ic.gov"
+                  "url": "https://omics-fips.us-gov-east-1.amazonaws.com"
                 }
               },
               "params": {
-                "UseDualStack": false,
-                "Region": "us-iso-east-1",
-                "UseFIPS": true
+                "Region": "us-gov-east-1",
+                "UseFIPS": true,
+                "UseDualStack": false
               }
             },
             {
-              "documentation": "For region us-iso-east-1 with FIPS disabled and DualStack enabled",
+              "documentation": "For region us-gov-east-1 with FIPS disabled and DualStack enabled",
               "expect": {
-                "error": "DualStack is enabled but this partition does not support DualStack"
+                "endpoint": {
+                  "url": "https://omics.us-gov-east-1.api.aws"
+                }
               },
               "params": {
-                "UseDualStack": true,
-                "Region": "us-iso-east-1",
-                "UseFIPS": false
+                "Region": "us-gov-east-1",
+                "UseFIPS": false,
+                "UseDualStack": true
               }
             },
             {
-              "documentation": "For region us-iso-east-1 with FIPS disabled and DualStack disabled",
+              "documentation": "For region us-gov-east-1 with FIPS disabled and DualStack disabled",
               "expect": {
                 "endpoint": {
-                  "url": "https://omics.us-iso-east-1.c2s.ic.gov"
+                  "url": "https://omics.us-gov-east-1.amazonaws.com"
                 }
               },
               "params": {
-                "UseDualStack": false,
-                "Region": "us-iso-east-1",
-                "UseFIPS": false
+                "Region": "us-gov-east-1",
+                "UseFIPS": false,
+                "UseDualStack": false
               }
             },
             {
-              "documentation": "For region us-east-1 with FIPS enabled and DualStack enabled",
+              "documentation": "For region us-iso-east-1 with FIPS enabled and DualStack enabled",
               "expect": {
-                "endpoint": {
-                  "url": "https://omics-fips.us-east-1.api.aws"
-                }
+                "error": "FIPS and DualStack are enabled, but this partition does not support one or both"
               },
               "params": {
-                "UseDualStack": true,
-                "Region": "us-east-1",
-                "UseFIPS": true
+                "Region": "us-iso-east-1",
+                "UseFIPS": true,
+                "UseDualStack": true
               }
             },
             {
-              "documentation": "For region us-east-1 with FIPS enabled and DualStack disabled",
+              "documentation": "For region us-iso-east-1 with FIPS enabled and DualStack disabled",
               "expect": {
                 "endpoint": {
-                  "url": "https://omics-fips.us-east-1.amazonaws.com"
+                  "url": "https://omics-fips.us-iso-east-1.c2s.ic.gov"
                 }
               },
               "params": {
-                "UseDualStack": false,
-                "Region": "us-east-1",
-                "UseFIPS": true
+                "Region": "us-iso-east-1",
+                "UseFIPS": true,
+                "UseDualStack": false
               }
             },
             {
-              "documentation": "For region us-east-1 with FIPS disabled and DualStack enabled",
+              "documentation": "For region us-iso-east-1 with FIPS disabled and DualStack enabled",
               "expect": {
-                "endpoint": {
-                  "url": "https://omics.us-east-1.api.aws"
-                }
+                "error": "DualStack is enabled but this partition does not support DualStack"
               },
               "params": {
-                "UseDualStack": true,
-                "Region": "us-east-1",
-                "UseFIPS": false
+                "Region": "us-iso-east-1",
+                "UseFIPS": false,
+                "UseDualStack": true
               }
             },
             {
-              "documentation": "For region us-east-1 with FIPS disabled and DualStack disabled",
+              "documentation": "For region us-iso-east-1 with FIPS disabled and DualStack disabled",
               "expect": {
                 "endpoint": {
-                  "url": "https://omics.us-east-1.amazonaws.com"
+                  "url": "https://omics.us-iso-east-1.c2s.ic.gov"
                 }
               },
               "params": {
-                "UseDualStack": false,
-                "Region": "us-east-1",
-                "UseFIPS": false
+                "Region": "us-iso-east-1",
+                "UseFIPS": false,
+                "UseDualStack": false
               }
             },
             {
@@ -9638,9 +9659,9 @@
                 "error": "FIPS and DualStack are enabled, but this partition does not support one or both"
               },
               "params": {
-                "UseDualStack": true,
                 "Region": "us-isob-east-1",
-                "UseFIPS": true
+                "UseFIPS": true,
+                "UseDualStack": true
               }
             },
             {
@@ -9651,9 +9672,9 @@
                 }
               },
               "params": {
-                "UseDualStack": false,
                 "Region": "us-isob-east-1",
-                "UseFIPS": true
+                "UseFIPS": true,
+                "UseDualStack": false
               }
             },
             {
@@ -9662,9 +9683,9 @@
                 "error": "DualStack is enabled but this partition does not support DualStack"
               },
               "params": {
-                "UseDualStack": true,
                 "Region": "us-isob-east-1",
-                "UseFIPS": false
+                "UseFIPS": false,
+                "UseDualStack": true
               }
             },
             {
@@ -9675,22 +9696,35 @@
                 }
               },
               "params": {
-                "UseDualStack": false,
                 "Region": "us-isob-east-1",
-                "UseFIPS": false
+                "UseFIPS": false,
+                "UseDualStack": false
               }
             },
             {
-              "documentation": "For custom endpoint with fips disabled and dualstack disabled",
+              "documentation": "For custom endpoint with region set and fips disabled and dualstack disabled",
               "expect": {
                 "endpoint": {
                   "url": "https://example.com"
                 }
               },
               "params": {
-                "UseDualStack": false,
                 "Region": "us-east-1",
                 "UseFIPS": false,
+                "UseDualStack": false,
+                "Endpoint": "https://example.com"
+              }
+            },
+            {
+              "documentation": "For custom endpoint with region not set and fips disabled and dualstack disabled",
+              "expect": {
+                "endpoint": {
+                  "url": "https://example.com"
+                }
+              },
+              "params": {
+                "UseFIPS": false,
+                "UseDualStack": false,
                 "Endpoint": "https://example.com"
               }
             },
@@ -9700,9 +9734,9 @@
                 "error": "Invalid Configuration: FIPS and custom endpoint are not supported"
               },
               "params": {
-                "UseDualStack": false,
                 "Region": "us-east-1",
                 "UseFIPS": true,
+                "UseDualStack": false,
                 "Endpoint": "https://example.com"
               }
             },
@@ -9712,11 +9746,17 @@
                 "error": "Invalid Configuration: Dualstack and custom endpoint are not supported"
               },
               "params": {
-                "UseDualStack": true,
                 "Region": "us-east-1",
                 "UseFIPS": false,
+                "UseDualStack": true,
                 "Endpoint": "https://example.com"
               }
+            },
+            {
+              "documentation": "Missing region",
+              "expect": {
+                "error": "Invalid Configuration: Missing Region"
+              }
             }
           ],
           "version": "1.0"
@@ -10098,6 +10138,12 @@
           "traits": {
             "smithy.api#documentation": "<p>\n      Where the source originated.\n    </p>"
           }
+        },
+        "creationType": {
+          "target": "com.amazonaws.omics#CreationType",
+          "traits": {
+            "smithy.api#documentation": "<p>\n      The creation type of the read set.\n    </p>"
+          }
         }
       },
       "traits": {
@@ -10274,6 +10320,12 @@
           "traits": {
             "smithy.api#documentation": "<p>\n      The status for a read set. It provides more detail as to why the read set has a status. \n    </p>"
           }
+        },
+        "creationType": {
+          "target": "com.amazonaws.omics#CreationType",
+          "traits": {
+            "smithy.api#documentation": "<p>\n      The creation type of the read set.\n    </p>"
+          }
         }
       },
       "traits": {