diff --git a/.changes/next-release/bugfix-region-endpoint-0496c4f3.json b/.changes/next-release/bugfix-region-endpoint-0496c4f3.json
new file mode 100644
index 0000000000..14e33a8306
--- /dev/null
+++ b/.changes/next-release/bugfix-region-endpoint-0496c4f3.json
@@ -0,0 +1,5 @@
+{
+  "type": "bugfix",
+  "category": "region endpoint",
+  "description": "add endpoint suffix for a region"
+}
\ No newline at end of file
diff --git a/lib/region_config.js b/lib/region_config.js
index f2809c5216..04aa8de1b4 100644
--- a/lib/region_config.js
+++ b/lib/region_config.js
@@ -92,6 +92,7 @@ function getEndpointSuffix(region) {
     '^us\\-iso\\-\\w+\\-\\d+$': 'c2s.ic.gov',
     '^us\\-isob\\-\\w+\\-\\d+$': 'sc2s.sgov.gov',
     '^eu\\-isoe\\-west\\-1$': 'cloud.adc-e.uk',
+    '^us\\-isof\\-\\w+\\-\\d+$': 'csp.hci.ic.gov',
   };
   var defaultSuffix = 'amazonaws.com';
   var regexes = Object.keys(regionRegexes);
diff --git a/test/region_config.spec.js b/test/region_config.spec.js
index 4d7ddc0e42..5712c1b051 100644
--- a/test/region_config.spec.js
+++ b/test/region_config.spec.js
@@ -139,6 +139,10 @@ describe('region_config.js', function() {
   it('resolves the endpoint suffix for eu-isoe-west-1', function() {
     expect(getEndpointSuffix('eu-isoe-west-1')).to.equal('cloud.adc-e.uk');
   });
+
+  it('resolves the endpoint suffix for us-isof-south-1', function() {
+    expect(getEndpointSuffix('us-isof-south-1')).to.equal('csp.hci.ic.gov');
+  });
 });
 
 describe('region_config_data.json', function() {