diff --git a/packages/@jsii/python-runtime/setup.py b/packages/@jsii/python-runtime/setup.py
index 440c5e9305..e61844806e 100644
--- a/packages/@jsii/python-runtime/setup.py
+++ b/packages/@jsii/python-runtime/setup.py
@@ -32,7 +32,7 @@
     install_requires=[
         "attrs~=21.2",
         "cattrs~=1.0.0 ; python_version < '3.7'",
-        "cattrs>=1.8,<1.11 ; python_version >= '3.7'",
+        "cattrs>=1.8,<22.2 ; python_version >= '3.7'",
         "importlib_resources ; python_version < '3.7'",
         "python-dateutil",
         "typing_extensions>=3.7,<5.0",