Update README.md

README.md

@@ -34,14 +34,15 @@ All the results in FitHiChIP, like the significant loops, HiChIP peak calling, p
 https://doi.org/10.5281/zenodo.3255048
 
 
-Release notes corresponding to version 9.1 (in progress) (March 15, 2021)
+Major release - version 9.1 (October, 2021)
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 	1. Upgraded merge filtering routine to support Python3, instead of deprecated python2
-	2. Updated README and manual
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+	2. Added support for circular genome. In such a case, the genomic distance between interacting fragments are computed using the minimum of their linear distance and their circular genome specific distance. The configuration file now has a parameter "CircularGenome" which, if 1, denotes that the reference genome is circular. **Note** User must provide the appropriate chromosome size file in the configuration options.
+	3. Updated the genomic distance based filtering of interactions according to the circular genome.
+	4. The FitHiChIP output file (*fithic*.bed) has now one extra field, namely "Dist" (20th column) which explicitly mentions the genomic distance between the interacting fragments. Useful for the circular genome.
+	5. Updated the HiChIP peak calling routine as well. Previously, all the reads from DE, SC, RE and valid pairs (from HiC-pro output) were required as the input set of reads. Now we've relaxed such constraints. If the user does not provide any DE, RE, or SC reads, but only provides the valid pairs, HiChIP peaks will be estimated from the valid pairs itself.	
+	6. Updated README and manual
 
 Release notes corresponding to version 9.0 (January 10, 2021)
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