diff --git a/src/xterm.rs b/src/xterm.rs
index 7e77174..e33e804 100644
--- a/src/xterm.rs
+++ b/src/xterm.rs
@@ -13,6 +13,10 @@ const QUERY_FG: &[u8] = b"\x1b]10;?";
 const FG_RESPONSE_PREFIX: &[u8] = b"\x1b]10;";
 const QUERY_BG: &[u8] = b"\x1b]11;?";
 const BG_RESPONSE_PREFIX: &[u8] = b"\x1b]11;";
+const ST: &[u8] = b"\x1b\\";
+const DA1: &[u8] = b"\x1b[c";
+const ESC: u8 = 0x1b;
+const BEL: u8 = 0x07;
 
 pub(crate) fn foreground_color(options: QueryOptions) -> Result<Color> {
     let quirks = terminal_quirks_from_env();
@@ -68,11 +72,6 @@ fn map_timed_out_err(timeout: Duration) -> impl Fn(Error) -> Error {
     }
 }
 
-const ST: &[u8] = b"\x1b\\";
-const DA1: &[u8] = b"\x1b[c";
-const ESC: u8 = 0x1b;
-const BEL: u8 = 0x07;
-
 fn parse_response(response: Vec<u8>, prefix: &[u8]) -> Result<Color> {
     response
         .strip_prefix(prefix)
diff --git a/src/xterm/quirks.rs b/src/xterm/quirks.rs
index 2765d9e..2132376 100644
--- a/src/xterm/quirks.rs
+++ b/src/xterm/quirks.rs
@@ -1,3 +1,4 @@
+use super::{BEL, ST};
 use std::env;
 use std::io::{self, Write};
 use std::sync::OnceLock;
@@ -14,6 +15,7 @@ fn terminal_quirk_from_env_eager() -> TerminalQuirks {
     match env::var("TERM") {
         Ok(term) if term == "dumb" => Barebones,
         Ok(term) if term == "rxvt-unicode" || term.starts_with("rxvt-unicode-") => Urxvt,
+        Ok(term) if term == "screen" || term.starts_with("screen.") => Screen,
         Ok(_) | Err(_) => None,
     }
 }
@@ -23,6 +25,7 @@ pub(super) enum TerminalQuirks {
     None,
     Barebones,
     Urxvt,
+    Screen,
 }
 
 impl TerminalQuirks {
@@ -33,9 +36,6 @@ impl TerminalQuirks {
     }
 
     pub(super) fn string_terminator(&self) -> &[u8] {
-        const ST: &[u8] = b"\x1b\\";
-        const BEL: u8 = 0x07;
-
         if let TerminalQuirks::Urxvt = self {
             // The currently released version has a bug where it terminates the response with `ESC` instead of `ST`.
             // Fixed by revision [1.600](http://cvs.schmorp.de/rxvt-unicode/src/command.C?revision=1.600&view=markup).
@@ -47,10 +47,119 @@ impl TerminalQuirks {
     }
 
     pub(super) fn write_all(&self, w: &mut dyn Write, bytes: &[u8]) -> io::Result<()> {
-        w.write_all(bytes)
+        if let TerminalQuirks::Screen = self {
+            screen::write_to_host_terminal(w, bytes)
+        } else {
+            w.write_all(bytes)
+        }
     }
 
     pub(super) fn write_string_terminator(&self, writer: &mut dyn Write) -> io::Result<()> {
         self.write_all(writer, self.string_terminator())
     }
 }
+
+// Screen breaks one of our fundamental assumptions:
+// It responds to `DA1` *before* responding to `OSC 10`.
+// To work around this we wrap our query in a `DCS` / `ST` pair.
+//
+// This directs screen to send our query to the underlying terminal instead of
+// interpreting our query itself. Hopefully the underlying terminal is more
+// *sensible* about order...
+mod screen {
+    use super::*;
+    use crate::xterm::{ESC, ST};
+    use memchr::memchr_iter;
+
+    /// From the [manual](https://www.gnu.org/software/screen/manual/html_node/Control-Sequences.html):
+    /// > Device Control String \
+    /// > Outputs a string directly to the host
+    /// > terminal without interpretation.
+    const DCS: &[u8] = b"\x1bP";
+
+    pub(super) fn write_to_host_terminal(w: &mut dyn Write, mut bytes: &[u8]) -> io::Result<()> {
+        loop {
+            // If our query contains `ST` we need to split it across multiple
+            // `DCS` / `ST` pairs to avoid screen from interpreting our `ST` as
+            // the terminator for the `DCS` sequence.
+            if let Some(index) = find_st(bytes) {
+                write_to_host_terminal_unchecked(w, &bytes[..index])?;
+                write_to_host_terminal_unchecked(w, &[ESC])?;
+                write_to_host_terminal_unchecked(w, &[b'\\'])?;
+                bytes = &bytes[(index + ST.len())..];
+            } else {
+                write_to_host_terminal_unchecked(w, bytes)?;
+                break;
+            }
+        }
+
+        Ok(())
+    }
+
+    fn write_to_host_terminal_unchecked(w: &mut dyn Write, bytes: &[u8]) -> io::Result<()> {
+        if !bytes.is_empty() {
+            w.write_all(DCS)?;
+            w.write_all(bytes)?;
+            w.write_all(ST)?;
+        }
+        Ok(())
+    }
+
+    fn find_st(haystack: &[u8]) -> Option<usize> {
+        memchr_iter(ESC, haystack)
+            .filter_map(|index| {
+                let next_byte = *haystack.get(index + 1)?;
+                (next_byte == b'\\').then_some(index)
+            })
+            .next()
+    }
+
+    #[cfg(test)]
+    mod tests {
+        use super::*;
+        use crate::fmt::CaretNotation;
+
+        #[test]
+        fn wraps_query_between_dcs_and_st() {
+            let expected = b"\x1bP\x1b[c\x1b\\";
+            let mut actual = Vec::new();
+            write_to_host_terminal(&mut actual, b"\x1b[c").unwrap_or_else(|_| unreachable!());
+            assert_eq!(to_string(expected.as_slice()), to_string(&actual));
+        }
+
+        #[test]
+        fn splits_st_among_multiple_dcs_and_st_pairs() {
+            let expected = b"\x1bP\x1b]11;?\x1b\\\x1bP\x1b\x1b\\\x1bP\\\x1b\\";
+            let mut actual = Vec::new();
+            write_to_host_terminal(&mut actual, b"\x1b]11;?\x1b\\")
+                .unwrap_or_else(|_| unreachable!());
+            assert_eq!(to_string(expected.as_slice()), to_string(&actual));
+        }
+
+        #[test]
+        fn finds_st_at_start() {
+            assert_eq!(Some(0), find_st(ST));
+        }
+
+        #[test]
+        fn finds_st_after_esc() {
+            assert_eq!(Some(1), find_st(&[ESC, ESC, b'\\']))
+        }
+
+        #[test]
+        fn finds_first_esc() {
+            assert_eq!(
+                Some(3),
+                find_st(&[b'f', b'o', b'o', ESC, b'\\', ESC, b'\\'])
+            )
+        }
+
+        fn to_string(input: &[u8]) -> String {
+            use std::str::from_utf8;
+            format!(
+                "{}",
+                CaretNotation(from_utf8(input).expect("valid utf-8 data"))
+            )
+        }
+    }
+}