diff --git a/recipes/confindr/meta.yaml b/recipes/confindr/meta.yaml
index 3bcd0c3415826..20bb623ad1856 100644
--- a/recipes/confindr/meta.yaml
+++ b/recipes/confindr/meta.yaml
@@ -1,5 +1,5 @@
-{% set version = "0.4.1" %}
-{% set sha256 = "f49a26afbc5aae4d3039fe01c7b193dff19cf2bdb5e6b6c2ddfdc50d638ea818" %}
+{% set version = "0.4.2" %}
+{% set sha256 = "17777e432a0f63c4612d3ea3f2dbe96395202f2e397a9f79efcc7ce8570cc532" %}
 
 package:
   name: confindr
@@ -21,7 +21,7 @@ requirements:
   run:
     - python >=3
     - biopython
-    - pysam
+    - pysam >=0.15
     - pytest
     - bbmap >=38
     - mash >=2