diff --git a/app/brave_main_delegate.cc b/app/brave_main_delegate.cc
index bd01ff807d74..26b6df5ec5b8 100644
--- a/app/brave_main_delegate.cc
+++ b/app/brave_main_delegate.cc
@@ -104,6 +104,7 @@ bool BraveMainDelegate::BasicStartupComplete(int* exit_code) {
   base::CommandLine& command_line =
       *base::CommandLine::ForCurrentProcess();
   command_line.AppendSwitch(switches::kEnableTabAudioMuting);
+  command_line.AppendSwitch(switches::kDisableDomainReliability);
 
   std::stringstream enabled_features;
   enabled_features << features::kEnableEmojiContextMenu.name
diff --git a/app/brave_main_delegate_browsertest.cc b/app/brave_main_delegate_browsertest.cc
new file mode 100644
index 000000000000..73f71abd3609
--- /dev/null
+++ b/app/brave_main_delegate_browsertest.cc
@@ -0,0 +1,18 @@
+/* This Source Code Form is subject to the terms of the Mozilla Public
+ * License, v. 2.0. If a copy of the MPL was not distributed with this file,
+ * You can obtain one at http://mozilla.org/MPL/2.0/. */
+
+#include "chrome/browser/ui/browser.h"
+#include "chrome/test/base/in_process_browser_test.h"
+#include "chrome/common/chrome_switches.h"
+#include "chrome/browser/domain_reliability/service_factory.h"
+#include "components/domain_reliability/service.h"
+
+using BraveMainDelegateBrowserTest = InProcessBrowserTest;
+
+IN_PROC_BROWSER_TEST_F(BraveMainDelegateBrowserTest, DomainReliabilityServiceDisabled) {
+  EXPECT_TRUE(base::CommandLine::ForCurrentProcess()->HasSwitch(
+      switches::kDisableDomainReliability));
+  ASSERT_EQ(domain_reliability::DomainReliabilityServiceFactory::GetForBrowserContext(
+        ((content::BrowserContext *)browser()->profile())), nullptr);
+}
diff --git a/browser/brave_profile_prefs_browsertest.cc b/browser/brave_profile_prefs_browsertest.cc
index bfee9bbbd72b..ffd726de9cbc 100644
--- a/browser/brave_profile_prefs_browsertest.cc
+++ b/browser/brave_profile_prefs_browsertest.cc
@@ -17,6 +17,9 @@ using BraveProfilePrefsBrowserTest = InProcessBrowserTest;
 IN_PROC_BROWSER_TEST_F(BraveProfilePrefsBrowserTest, DownloadPromptDefault) {
   EXPECT_TRUE(
       browser()->profile()->GetPrefs()->GetBoolean(prefs::kPromptForDownload));
+}
+
+IN_PROC_BROWSER_TEST_F(BraveProfilePrefsBrowserTest, WidevineOptInDisabledByDefault) {
   EXPECT_FALSE(
       browser()->profile()->GetPrefs()->GetBoolean(kWidevineOptedIn));
 }
diff --git a/test/BUILD.gn b/test/BUILD.gn
index a19ca901da83..2845e6e95339 100644
--- a/test/BUILD.gn
+++ b/test/BUILD.gn
@@ -133,6 +133,7 @@ static_library("browser_tests_runner") {
 
 test("brave_browser_tests") {
   sources = [
+    "//brave/app/brave_main_delegate_browsertest.cc",
     "//brave/chromium_src/third_party/blink/renderer/modules/battery/navigator_batterytest.cc",
     "//brave/chromium_src/third_party/blink/renderer/modules/bluetooth/navigator_bluetoothtest.cc",
     "//brave/chromium_src/third_party/blink/renderer/modules/credentialmanager/credentials_containertest.cc",