diff --git a/apps/web/app/api/cron/syncAppMeta/route.ts b/apps/web/app/api/cron/syncAppMeta/route.ts
index c5479da49536c7..927fe991bb9fd3 100644
--- a/apps/web/app/api/cron/syncAppMeta/route.ts
+++ b/apps/web/app/api/cron/syncAppMeta/route.ts
@@ -3,6 +3,7 @@ import type { NextRequest } from "next/server";
 import { NextResponse } from "next/server";
 
 import { getAppWithMetadata } from "@calcom/app-store/_appRegistry";
+import { shouldEnableApp } from "@calcom/app-store/_utils/validateAppKeys";
 import logger from "@calcom/lib/logger";
 import { prisma } from "@calcom/prisma";
 import type { AppCategories, Prisma } from "@calcom/prisma/client";
@@ -48,6 +49,17 @@ async function postHandler(request: NextRequest) {
       updates["dirName"] = app.dirName ?? app.slug;
     }
 
+    // Ensure app is only enabled if it has valid keys (or doesn't require keys)
+    const shouldBeEnabled = shouldEnableApp(dbApp.dirName, dbApp.keys);
+    if (dbApp.enabled !== shouldBeEnabled) {
+      updates["enabled"] = shouldBeEnabled;
+      if (!shouldBeEnabled && dbApp.enabled) {
+        log.warn(
+          `⚠️ Disabling app ${dbApp.slug} - required keys are missing or invalid. Please configure keys in admin settings.`
+        );
+      }
+    }
+
     if (Object.keys(updates).length > 0) {
       log.info(`🔨 Updating app ${dbApp.slug} with ${Object.keys(updates).join(", ")}`);
       if (!isDryRun) {
diff --git a/packages/app-store/_utils/validateAppKeys.test.ts b/packages/app-store/_utils/validateAppKeys.test.ts
new file mode 100644
index 00000000000000..94957d2fb4be40
--- /dev/null
+++ b/packages/app-store/_utils/validateAppKeys.test.ts
@@ -0,0 +1,167 @@
+import { describe, expect, it } from "vitest";
+
+import { shouldEnableApp } from "./validateAppKeys";
+
+describe("shouldEnableApp", () => {
+  describe("Apps without key schemas", () => {
+    it("should return true for apps that don't require keys", () => {
+      // Use a dirName that doesn't have a schema (e.g., a non-existent app)
+      const result = shouldEnableApp("non-existent-app", null);
+      expect(result).toBe(true);
+    });
+
+    it("should return true even if keys are null for apps without schemas", () => {
+      const result = shouldEnableApp("non-existent-app", null);
+      expect(result).toBe(true);
+    });
+
+    it("should return true even if keys are empty object for apps without schemas", () => {
+      const result = shouldEnableApp("non-existent-app", {});
+      expect(result).toBe(true);
+    });
+  });
+
+  describe("Apps with key schemas", () => {
+    it("should return false when keys are null", () => {
+      // dailyvideo requires api_key and has scale_plan with default
+      const result = shouldEnableApp("dailyvideo", null);
+      expect(result).toBe(false);
+    });
+
+    it("should return false when keys are undefined", () => {
+      const result = shouldEnableApp("dailyvideo", undefined);
+      expect(result).toBe(false);
+    });
+
+    it("should return false when keys is an empty object", () => {
+      // Empty object doesn't have required api_key field
+      const result = shouldEnableApp("dailyvideo", {});
+      expect(result).toBe(false);
+    });
+
+    it("should return false when keys is an array", () => {
+      const result = shouldEnableApp("dailyvideo", [] as any);
+      expect(result).toBe(false);
+    });
+
+    it("should return false when keys is a string", () => {
+      const result = shouldEnableApp("dailyvideo", "invalid" as any);
+      expect(result).toBe(false);
+    });
+
+    it("should return false when keys is a number", () => {
+      const result = shouldEnableApp("dailyvideo", 123 as any);
+      expect(result).toBe(false);
+    });
+
+    it("should return false when required keys are missing", () => {
+      // Missing required api_key field
+      const result = shouldEnableApp("dailyvideo", {
+        scale_plan: "true",
+      });
+      expect(result).toBe(false);
+    });
+
+    it("should return false when required keys are empty strings", () => {
+      // api_key is empty string, which violates .min(1)
+      const result = shouldEnableApp("dailyvideo", {
+        api_key: "",
+        scale_plan: "false",
+      });
+      expect(result).toBe(false);
+    });
+
+    it("should return true when all required keys are present and valid", () => {
+      const result = shouldEnableApp("dailyvideo", {
+        api_key: "valid-api-key",
+        scale_plan: "false",
+      });
+      expect(result).toBe(true);
+    });
+
+    it("should return true when required keys are present and optional fields use defaults", () => {
+      // scale_plan has a default, so we can omit it
+      const result = shouldEnableApp("dailyvideo", {
+        api_key: "valid-api-key",
+      });
+      expect(result).toBe(true);
+    });
+
+    it("should return false when keys have wrong types", () => {
+      // api_key should be string, not number
+      const result = shouldEnableApp("dailyvideo", {
+        api_key: 123 as any,
+        scale_plan: "false",
+      });
+      expect(result).toBe(false);
+    });
+  });
+
+  describe("Apps with multiple required fields", () => {
+    it("should return false when any required field is missing", () => {
+      // vital requires mode, region, api_key, and webhook_secret
+      const result = shouldEnableApp("vital", {
+        mode: "sandbox",
+        region: "us",
+        api_key: "test-key",
+        // Missing webhook_secret
+      });
+      expect(result).toBe(false);
+    });
+
+    it("should return true when all required fields are present", () => {
+      const result = shouldEnableApp("vital", {
+        mode: "sandbox",
+        region: "us",
+        api_key: "test-key",
+        webhook_secret: "test-secret",
+      });
+      expect(result).toBe(true);
+    });
+
+    it("should return false when any required field is empty", () => {
+      const result = shouldEnableApp("vital", {
+        mode: "",
+        region: "us",
+        api_key: "test-key",
+        webhook_secret: "test-secret",
+      });
+      expect(result).toBe(false);
+    });
+  });
+  
+  describe("Apps with empty key schemas (user-configured apps like PayPal, GTM)", () => {
+    // These apps have `appKeysSchema = z.object({})` - they don't need server-side keys
+    // Users configure them after installation, so they should always be enabled
+
+    it("should return true for PayPal when keys are null", () => {
+      const result = shouldEnableApp("paypal", null);
+      expect(result).toBe(true);
+    });
+
+    it("should return true for PayPal when keys are undefined", () => {
+      const result = shouldEnableApp("paypal", undefined);
+      expect(result).toBe(true);
+    });
+
+    it("should return true for PayPal when keys are empty object", () => {
+      const result = shouldEnableApp("paypal", {});
+      expect(result).toBe(true);
+    });
+
+    it("should return true for GTM when keys are null", () => {
+      const result = shouldEnableApp("gtm", null);
+      expect(result).toBe(true);
+    });
+
+    it("should return true for GTM when keys are undefined", () => {
+      const result = shouldEnableApp("gtm", undefined);
+      expect(result).toBe(true);
+    });
+
+    it("should return true for GA4 when keys are null", () => {
+      const result = shouldEnableApp("ga4", null);
+      expect(result).toBe(true);
+    });
+  });
+});
diff --git a/packages/app-store/_utils/validateAppKeys.ts b/packages/app-store/_utils/validateAppKeys.ts
new file mode 100644
index 00000000000000..72369ea25fd3dc
--- /dev/null
+++ b/packages/app-store/_utils/validateAppKeys.ts
@@ -0,0 +1,28 @@
+import { appKeysSchemas } from "@calcom/app-store/apps.keys-schemas.generated";
+import type { Prisma } from "@calcom/prisma/client";
+/**
+ * Determines if an app should be enabled based on whether it has valid keys.
+ * This is used by app registration scripts to prevent enabling apps without proper configuration.
+ * 
+ * @param dirName - The directory name of the app
+ * @param keys - The keys object (can be undefined/null)
+ */
+export function shouldEnableApp(dirName: string, keys?: Prisma.JsonValue | null): boolean {
+  const keySchema = appKeysSchemas[dirName as keyof typeof appKeysSchemas];
+  
+  // If no schema, the app doesn't require keys - can be enabled
+  if (!keySchema) {
+    return true;
+  }
+
+  // If keys is null/undefined, check if the schema accepts an empty object.
+  if (keys === null || keys === undefined) {
+    const emptyObjectResult = keySchema.safeParse({});
+    return emptyObjectResult.success;
+  }
+
+
+  // Validate keys against schema
+  const result = keySchema.safeParse(keys);
+  return result.success;
+}
diff --git a/packages/features/apps/repository/PrismaAppRepository.ts b/packages/features/apps/repository/PrismaAppRepository.ts
index 80caf3e2167e3c..79119e73856ff4 100644
--- a/packages/features/apps/repository/PrismaAppRepository.ts
+++ b/packages/features/apps/repository/PrismaAppRepository.ts
@@ -1,6 +1,7 @@
 import { captureException } from "@sentry/nextjs";
 
 import { appStoreMetadata } from "@calcom/app-store/appStoreMetaData";
+import { shouldEnableApp } from "@calcom/app-store/_utils/validateAppKeys";
 import { prisma } from "@calcom/prisma";
 import type { Prisma } from "@calcom/prisma/client";
 
@@ -12,13 +13,15 @@ export class PrismaAppRepository {
       throw new Error(`App ${dirName} not found`);
     }
 
+    // Only enable if keys are valid (or app doesn't require keys)
+    const enabled = shouldEnableApp(dirName, keys as Prisma.JsonValue);
     await prisma.app.create({
       data: {
         slug: appMetadata.slug,
         categories: appMetadata.categories,
         dirName: dirName,
         keys,
-        enabled: true,
+        enabled,
       },
     });
   }
diff --git a/scripts/seed-app-store.ts b/scripts/seed-app-store.ts
index e5dea33b22dc99..22e0725a641e69 100644
--- a/scripts/seed-app-store.ts
+++ b/scripts/seed-app-store.ts
@@ -6,6 +6,7 @@ import dotEnv from "dotenv";
 import path from "node:path"
 
 import { appStoreMetadata } from "@calcom/app-store/appStoreMetaData";
+import { shouldEnableApp } from "@calcom/app-store/_utils/validateAppKeys";
 import prisma from "@calcom/prisma";
 import type { Prisma } from "@calcom/prisma/client";
 import { AppCategories } from "@calcom/prisma/enums";
@@ -48,8 +49,9 @@ async function createApp(
       },
     });
 
-    // We need to enable seeded apps as they are used in tests.
-    const data = { slug, dirName, categories, keys, enabled: true };
+    // Only enable apps if they have valid keys (or don't require keys)
+    const enabled = shouldEnableApp(dirName, keys as Prisma.JsonValue);
+    const data = { slug, dirName, categories, keys, enabled };
 
     if (!foundApp) {
       await prisma.app.create({