diff --git a/packages/react/src/components/DatePicker/DatePicker.js b/packages/react/src/components/DatePicker/DatePicker.js
index ca800fdf8552..f546d0f91083 100644
--- a/packages/react/src/components/DatePicker/DatePicker.js
+++ b/packages/react/src/components/DatePicker/DatePicker.js
@@ -12,6 +12,7 @@ import flatpickr from 'flatpickr';
 import l10n from 'flatpickr/dist/l10n/index';
 import { settings } from 'carbon-components';
 import DatePickerInput from '../DatePickerInput';
+import carbonFlatpickrAppendToPlugin from './plugins/appendToPlugin';
 import carbonFlatpickrFixEventsPlugin from './plugins/fixEventsPlugin';
 import carbonFlatpickrRangePlugin from './plugins/rangePlugin';
 import { match, keys } from '../../internal/keyboard';
@@ -340,7 +341,6 @@ export default class DatePicker extends Component {
         this.cal = new flatpickr(this.inputField, {
           disableMobile: true,
           defaultDate: value,
-          appendTo,
           mode: datePickerType,
           allowInput: true,
           dateFormat: dateFormat,
@@ -351,6 +351,11 @@ export default class DatePicker extends Component {
             datePickerType === 'range'
               ? new carbonFlatpickrRangePlugin({ input: this.toInputField })
               : () => {},
+            appendTo
+              ? carbonFlatpickrAppendToPlugin({
+                  appendTo,
+                })
+              : () => {},
             carbonFlatpickrMonthSelectPlugin({
               selectorFlatpickrMonthYearContainer: '.flatpickr-current-month',
               selectorFlatpickrYearContainer: '.numInputWrapper',
diff --git a/packages/react/src/components/DatePicker/plugins/appendToPlugin.js b/packages/react/src/components/DatePicker/plugins/appendToPlugin.js
new file mode 100644
index 000000000000..bbf0976ee853
--- /dev/null
+++ b/packages/react/src/components/DatePicker/plugins/appendToPlugin.js
@@ -0,0 +1,64 @@
+/**
+ * @license
+ *
+ * Copyright IBM Corp. 2019
+ *
+ * This source code is licensed under the Apache-2.0 license found in the
+ * LICENSE file in the root directory of this source tree.
+ */
+
+/**
+ * @param {object} config Plugin configuration.
+ * @returns {Plugin} A Flatpickr plugin to put adjust the position of calendar dropdown.
+ */
+export default config => fp => {
+  /**
+   * Adjusts the floating meun position after Flatpicker sets it.
+   */
+  const handlePreCalendarPosition = () => {
+    Promise.resolve().then(() => {
+      const {
+        calendarContainer,
+        config: fpConfig,
+        _positionElement: positionElement,
+      } = fp;
+      const { appendTo } = fpConfig;
+      const {
+        left: containerLeft,
+        top: containerTop,
+      } = appendTo.getBoundingClientRect();
+      const {
+        left: refLeft,
+        bottom: refBottom,
+      } = positionElement.getBoundingClientRect();
+      if (
+        (appendTo !== appendTo.ownerDocument.body ||
+          containerLeft !== 0 ||
+          containerTop !== 0) &&
+        appendTo.ownerDocument.defaultView
+          .getComputedStyle(appendTo)
+          .getPropertyValue('position') === 'static'
+      ) {
+        throw new Error(
+          'Floating menu container must not have `position:static`.'
+        );
+      }
+      // `2` for negative mergin on calendar dropdown
+      calendarContainer.style.top = `${refBottom - containerTop + 2}px`;
+      calendarContainer.style.left = `${refLeft - containerLeft}px`;
+    });
+  };
+
+  /**
+   * Registers this Flatpickr plugin.
+   */
+  const register = () => {
+    fp.loadedPlugins.push('carbonFlatpickrAppendToPlugin');
+  };
+
+  return {
+    appendTo: config.appendTo,
+    onReady: register,
+    onPreCalendarPosition: handlePreCalendarPosition,
+  };
+};