diff --git a/pkg/cmd/roachtest/registry/test_spec.go b/pkg/cmd/roachtest/registry/test_spec.go
index a06ef44f92f1..98feded22697 100644
--- a/pkg/cmd/roachtest/registry/test_spec.go
+++ b/pkg/cmd/roachtest/registry/test_spec.go
@@ -224,6 +224,8 @@ func (l LeaseType) String() string {
 		return "epoch"
 	case ExpirationLeases:
 		return "expiration"
+	case LeaderLeases:
+		return "leader"
 	case MetamorphicLeases:
 		return "metamorphic"
 	default:
@@ -238,8 +240,11 @@ const (
 	EpochLeases
 	// ExpirationLeases uses expiration leases for all ranges.
 	ExpirationLeases
+	// LeaderLeases uses leader leases where possible.
+	LeaderLeases
 	// MetamorphicLeases randomly chooses epoch or expiration
-	// leases (across the entire cluster)
+	// leases (across the entire cluster).
+	// TODO(nvanbenschoten): add leader leases to this mix.
 	MetamorphicLeases
 )
 
diff --git a/pkg/cmd/roachtest/test_runner.go b/pkg/cmd/roachtest/test_runner.go
index f05b3acbe6f2..da14016903f2 100644
--- a/pkg/cmd/roachtest/test_runner.go
+++ b/pkg/cmd/roachtest/test_runner.go
@@ -903,8 +903,12 @@ func (r *testRunner) runWorker(
 				case registry.DefaultLeases:
 				case registry.EpochLeases:
 					c.clusterSettings["kv.expiration_leases_only.enabled"] = "false"
+					c.clusterSettings["kv.raft.leader_fortification.fraction_enabled"] = "0.0"
 				case registry.ExpirationLeases:
 					c.clusterSettings["kv.expiration_leases_only.enabled"] = "true"
+				case registry.LeaderLeases:
+					c.clusterSettings["kv.expiration_leases_only.enabled"] = "false"
+					c.clusterSettings["kv.raft.leader_fortification.fraction_enabled"] = "1.0"
 				case registry.MetamorphicLeases:
 					enabled := prng.Float64() < 0.5
 					c.status(fmt.Sprintf("metamorphically setting kv.expiration_leases_only.enabled = %t",
diff --git a/pkg/cmd/roachtest/tests/failover.go b/pkg/cmd/roachtest/tests/failover.go
index 91cc4d74d1dd..3db946f714bf 100644
--- a/pkg/cmd/roachtest/tests/failover.go
+++ b/pkg/cmd/roachtest/tests/failover.go
@@ -59,10 +59,20 @@ var rangeLeaseRenewalDuration = func() time.Duration {
 // requests are successful with nominal latencies. See also:
 // https://github.com/cockroachdb/cockroach/issues/103654
 func registerFailover(r registry.Registry) {
-	for _, leases := range []registry.LeaseType{registry.EpochLeases, registry.ExpirationLeases} {
+	leaseTypes := []registry.LeaseType{registry.EpochLeases, registry.ExpirationLeases, registry.LeaderLeases}
+	for _, leases := range leaseTypes {
 		var leasesStr string
-		if leases == registry.ExpirationLeases {
+		switch leases {
+		case registry.EpochLeases:
+			// TODO(nvanbenschoten): when leader leases become the default, we should
+			// change this to "/lease=epoch" and change leader leases to "".
+			leasesStr = ""
+		case registry.ExpirationLeases:
 			leasesStr = "/lease=expiration"
+		case registry.LeaderLeases:
+			leasesStr = "/lease=leader"
+		default:
+			panic(errors.AssertionFailedf("unknown lease type: %v", leases))
 		}
 
 		for _, readOnly := range []bool{false, true} {
diff --git a/pkg/cmd/roachtest/tests/tpcc.go b/pkg/cmd/roachtest/tests/tpcc.go
index 6361501e38f3..5705321cd756 100644
--- a/pkg/cmd/roachtest/tests/tpcc.go
+++ b/pkg/cmd/roachtest/tests/tpcc.go
@@ -1280,7 +1280,8 @@ type tpccBenchSpec struct {
 	// Encryption-At-Rest / EAR).
 	EncryptionEnabled bool
 	// ExpirationLeases enables use of expiration-based leases.
-	ExpirationLeases             bool
+	ExpirationLeases bool
+	// TODO(nvanbenschoten): add a leader lease variant.
 	EnableDefaultScheduledBackup bool
 	// SharedProcessMT, if true, indicates that the cluster should run in
 	// shared-process mode of multi-tenancy.