diff --git a/.github/workflows/test.yaml b/.github/workflows/test.yaml
index 5a9dea7d..26e34711 100644
--- a/.github/workflows/test.yaml
+++ b/.github/workflows/test.yaml
@@ -251,6 +251,28 @@ jobs:
         working-directory: build
         run: ctest --output-on-failure --build-config Debug -j 3
 
+  ninja_multi_config_cross_config:
+    name: Test Ninja Multi-Config Cross-Configs
+    runs-on: ubuntu-latest
+    steps:
+      - uses: actions/checkout@v4
+      - name: Install CMake
+        uses: corrosion-rs/install-cmake@v2
+        with:
+          cmake: 3.22.6
+          ninja: 1.10.0
+      # Install cbindgen before Rust to use recent default Rust version.
+      - name: Install cbindgen
+        run: cargo install cbindgen
+      - name: Install Rust
+        id: install_rust
+        uses: dtolnay/rust-toolchain@stable
+      - name: Configure
+        run: cmake -S. -Bbuild -G "Ninja Multi-Config" -DCMAKE_CROSS_CONFIGS="Debug;Release" -DCMAKE_DEFAULT_CONFIGS="Debug;Release"
+      - name: Run Tests
+        working-directory: build
+        run: ctest --output-on-failure -j 3 --build-config Debug
+
 
   test_cxxbridge:
     name: Test cxxbridge integration
diff --git a/test/CMakeLists.txt b/test/CMakeLists.txt
index 1a42ba4d..eb08deb7 100644
--- a/test/CMakeLists.txt
+++ b/test/CMakeLists.txt
@@ -112,6 +112,12 @@ function(corrosion_tests_add_test test_name bin_names)
     if(CMAKE_TOOLCHAIN_FILE)
         list(APPEND configure_cmake_args TOOLCHAIN_FILE "${CMAKE_TOOLCHAIN_FILE}")
     endif()
+    if(CMAKE_CROSS_CONFIGS)
+        list(APPEND configure_cmake_args CMAKE_CROSS_CONFIGS "${CMAKE_CROSS_CONFIGS}")
+    endif()
+    if(CMAKE_DEFAULT_CONFIGS)
+        list(APPEND configure_cmake_args CMAKE_DEFAULT_CONFIGS "${CMAKE_DEFAULT_CONFIGS}")
+    endif()
 
     add_test(NAME "${test_name}_build"
             COMMAND
diff --git a/test/ConfigureAndBuild.cmake b/test/ConfigureAndBuild.cmake
index c3017074..4845731c 100644
--- a/test/ConfigureAndBuild.cmake
+++ b/test/ConfigureAndBuild.cmake
@@ -23,6 +23,8 @@ set(oneValueArgs
     CARGO_PROFILE
     OSX_ARCHITECTURES
     TOOLCHAIN_FILE
+    CMAKE_CROSS_CONFIGS
+    CMAKE_DEFAULT_CONFIGS
 )
 set(multiValueArgs "PASS_THROUGH_ARGS")
 cmake_parse_arguments(TEST "${options}" "${oneValueArgs}"
@@ -59,6 +61,12 @@ endif()
 if(TEST_TOOLCHAIN_FILE)
     list(APPEND configure_args "-DCMAKE_TOOLCHAIN_FILE=${TEST_TOOLCHAIN_FILE}")
 endif()
+if(TEST_CMAKE_CROSS_CONFIGS)
+    list(APPEND configure_args "-DCMAKE_CROSS_CONFIGS=${TEST_CMAKE_CROSS_CONFIGS}")
+endif()
+if(TEST_CMAKE_DEFAULT_CONFIGS)
+    list(APPEND configure_args "-DCMAKE_DEFAULT_CONFIGS=${TEST_CMAKE_DEFAULT_CONFIGS}")
+endif()
 if(TEST_CARGO_PROFILE)
     list(APPEND configure_args "-DCARGO_PROFILE=${TEST_CARGO_PROFILE}")
 endif()