diff --git a/CHANGELOG.md b/CHANGELOG.md
index 4d72b6cd7494..c1fa63e5c91b 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -42,6 +42,7 @@ Every module contains its own CHANGELOG.md. Please refer to the module you are i
 
 ### Features
 
+* (client) [#19905](https://github.com/cosmos/cosmos-sdk/pull/19905) Add grpc client config to `client.toml`.
 * (runtime) [#19571](https://github.com/cosmos/cosmos-sdk/pull/19571) Implement `core/router.Service` it in runtime. This service is present in all modules (when using depinject).
 * (types) [#19164](https://github.com/cosmos/cosmos-sdk/pull/19164) Add a ValueCodec for the math.Uint type that can be used in collections maps.
 * (types) [#19281](https://github.com/cosmos/cosmos-sdk/pull/19281) Added a new method, `IsGT`, for `types.Coin`. This method is used to check if a `types.Coin` is greater than another `types.Coin`.
diff --git a/client/config/config.go b/client/config/config.go
index efe65bd34ec7..ae8cbb70584a 100644
--- a/client/config/config.go
+++ b/client/config/config.go
@@ -1,10 +1,15 @@
 package config
 
 import (
+	"crypto/tls"
 	"fmt"
 	"os"
 	"path/filepath"
 
+	"google.golang.org/grpc"
+	"google.golang.org/grpc/credentials"
+	"google.golang.org/grpc/credentials/insecure"
+
 	"github.com/cosmos/cosmos-sdk/client"
 	"github.com/cosmos/cosmos-sdk/client/flags"
 )
@@ -26,12 +31,19 @@ func DefaultConfig() *Config {
 type ClientConfig Config
 
 type Config struct {
-	ChainID               string `mapstructure:"chain-id" json:"chain-id"`
-	KeyringBackend        string `mapstructure:"keyring-backend" json:"keyring-backend"`
-	KeyringDefaultKeyName string `mapstructure:"keyring-default-keyname" json:"keyring-default-keyname"`
-	Output                string `mapstructure:"output" json:"output"`
-	Node                  string `mapstructure:"node" json:"node"`
-	BroadcastMode         string `mapstructure:"broadcast-mode" json:"broadcast-mode"`
+	ChainID               string     `mapstructure:"chain-id" json:"chain-id"`
+	KeyringBackend        string     `mapstructure:"keyring-backend" json:"keyring-backend"`
+	KeyringDefaultKeyName string     `mapstructure:"keyring-default-keyname" json:"keyring-default-keyname"`
+	Output                string     `mapstructure:"output" json:"output"`
+	Node                  string     `mapstructure:"node" json:"node"`
+	BroadcastMode         string     `mapstructure:"broadcast-mode" json:"broadcast-mode"`
+	GRPC                  GRPCConfig `mapstructure:",squash"`
+}
+
+// GRPCConfig holds the gRPC client configuration.
+type GRPCConfig struct {
+	Address  string `mapstructure:"grpc-address"  json:"grpc-address"`
+	Insecure bool   `mapstructure:"grpc-insecure"  json:"grpc-insecure"`
 }
 
 // ReadFromClientConfig reads values from client.toml file and updates them in client.Context
@@ -138,5 +150,35 @@ func CreateClientConfig(ctx client.Context, customClientTemplate string, customC
 		WithClient(client).
 		WithKeyring(keyring)
 
+	if conf.GRPC.Address != "" {
+		grpcClient, err := getGRPCClient(conf.GRPC)
+		if err != nil {
+			return ctx, fmt.Errorf("couldn't get grpc client: %w", err)
+		}
+
+		ctx = ctx.WithGRPCClient(grpcClient)
+	}
+
 	return ctx, nil
 }
+
+// getGRPCClient creates and returns a new gRPC client connection based on the GRPCConfig.
+// It determines the type of connection (secure or insecure) from the GRPCConfig and
+// uses the specified server address to establish the connection.
+func getGRPCClient(grpcConfig GRPCConfig) (*grpc.ClientConn, error) {
+	transport := grpc.WithTransportCredentials(credentials.NewTLS(&tls.Config{
+		MinVersion: tls.VersionTLS12,
+	}))
+
+	if grpcConfig.Insecure {
+		transport = grpc.WithTransportCredentials(insecure.NewCredentials())
+	}
+
+	dialOptions := []grpc.DialOption{transport}
+	grpcClient, err := grpc.Dial(grpcConfig.Address, dialOptions...)
+	if err != nil {
+		return nil, fmt.Errorf("failed to dial gRPC server at %s: %w", grpcConfig.Address, err)
+	}
+
+	return grpcClient, nil
+}
diff --git a/client/config/config_test.go b/client/config/config_test.go
index ceb052e8acd5..248ed47cea9c 100644
--- a/client/config/config_test.go
+++ b/client/config/config_test.go
@@ -87,7 +87,6 @@ gas-adjustment = {{ .GasConfig.GasAdjustment }}
 # Memo to include in all transactions.
 note = "{{ .Note }}"
 `
-
 	t.Run("custom template and config provided", func(t *testing.T) {
 		clientCtx, cleanup, err := initClientContextWithTemplate(t, "", customClientConfigTemplate, customClientConfig)
 		defer func() {
@@ -181,3 +180,23 @@ func TestConfigCmdEnvFlag(t *testing.T) {
 		})
 	}
 }
+
+func TestGRPCConfig(t *testing.T) {
+	expectedGRPCConfig := config.GRPCConfig{
+		Address:  "localhost:7070",
+		Insecure: true,
+	}
+
+	clientCfg := config.DefaultConfig()
+	clientCfg.GRPC = expectedGRPCConfig
+
+	t.Run("custom template with gRPC config", func(t *testing.T) {
+		clientCtx, cleanup, err := initClientContextWithTemplate(t, "", config.DefaultClientConfigTemplate, clientCfg)
+		defer cleanup()
+
+		require.NoError(t, err)
+
+		require.Equal(t, expectedGRPCConfig.Address, clientCtx.Viper.GetString("grpc-address"))
+		require.Equal(t, expectedGRPCConfig.Insecure, clientCtx.Viper.GetBool("grpc-insecure"))
+	})
+}
diff --git a/client/config/toml.go b/client/config/toml.go
index 7c43eccc15b8..35787219a236 100644
--- a/client/config/toml.go
+++ b/client/config/toml.go
@@ -8,7 +8,8 @@ import (
 	"github.com/spf13/viper"
 )
 
-const DefaultClientConfigTemplate = `# This is a TOML config file.
+const (
+	DefaultClientConfigTemplate = `# This is a TOML config file.
 # For more information, see https://github.com/toml-lang/toml
 
 ###############################################################################
@@ -27,7 +28,16 @@ output = "{{ .Output }}"
 node = "{{ .Node }}"
 # Transaction broadcasting mode (sync|async)
 broadcast-mode = "{{ .BroadcastMode }}"
+
+# gRPC server endpoint to which the client will connect.
+# It can be overwritten by the --grpc-addr flag in each command.
+grpc-address = "{{ .GRPC.Address }}"
+
+# Allow the gRPC client to connect over insecure channels.
+# It can be overwritten by the --grpc-insecure flag in each command.
+grpc-insecure = {{ .GRPC.Insecure }}
 `
+)
 
 var configTemplate *template.Template