diff --git a/src/Microsoft.Data.Sqlite.Core/SqliteConnectionFactory.cs b/src/Microsoft.Data.Sqlite.Core/SqliteConnectionFactory.cs
index 9e18fddff64..43c10f98d18 100644
--- a/src/Microsoft.Data.Sqlite.Core/SqliteConnectionFactory.cs
+++ b/src/Microsoft.Data.Sqlite.Core/SqliteConnectionFactory.cs
@@ -20,7 +20,15 @@ internal class SqliteConnectionFactory
         private Dictionary<string, SqliteConnectionPoolGroup> _poolGroups = new();
 
         protected SqliteConnectionFactory()
-            => _pruneTimer = new Timer(PruneCallback, null, TimeSpan.FromMinutes(4), TimeSpan.FromSeconds(30));
+        {
+            if (!AppContext.TryGetSwitch("Microsoft.Data.Sqlite.Issue26422", out var enabled) || !enabled)
+            {
+                AppDomain.CurrentDomain.DomainUnload += (_, _) => ClearPools();
+                AppDomain.CurrentDomain.ProcessExit += (_, _) => ClearPools();
+            }
+
+            _pruneTimer = new Timer(PruneCallback, null, TimeSpan.FromMinutes(4), TimeSpan.FromSeconds(30));
+        }
 
         public SqliteConnectionInternal GetConnection(SqliteConnection outerConnection)
         {