diff --git a/FSharp.Profiles.props b/FSharp.Profiles.props
index 4627fcace39..811ee0d0e40 100644
--- a/FSharp.Profiles.props
+++ b/FSharp.Profiles.props
@@ -23,7 +23,7 @@
   </PropertyGroup>
 
   <PropertyGroup Condition="'$(CheckNulls)' == 'true'">
-    <OtherFlags>$(OtherFlags) /checknulls</OtherFlags>
+    <Nullable>enable</Nullable>
   </PropertyGroup>
 
   <PropertyGroup Condition="'$(CheckNulls)' == 'false'">
diff --git a/src/FSharp.Build/Fsc.fs b/src/FSharp.Build/Fsc.fs
index 9de88c9dbca..24952eceea1 100644
--- a/src/FSharp.Build/Fsc.fs
+++ b/src/FSharp.Build/Fsc.fs
@@ -95,6 +95,7 @@ type public Fsc() as this =
     let mutable vslcid: string MaybeNull = null
     let mutable utf8output: bool = false
     let mutable useReflectionFreeCodeGen: bool = false
+    let mutable nullable: bool option = None
 
     /// Trim whitespace ... spaces, tabs, newlines,returns, Double quotes and single quotes
     let wsCharsToTrim = [| ' '; '\t'; '\"'; '\'' |]
@@ -205,6 +206,13 @@ type public Fsc() as this =
         if not tailcalls then
             builder.AppendSwitch("--tailcalls-")
 
+        match nullable with
+        | Some true ->
+            builder.AppendSwitch("--checknulls+")
+            builder.AppendSwitch("--define:NULLABLE")
+        | Some false -> builder.AppendSwitch("--checknulls-")
+        | None -> ()
+
         // PdbFile
         builder.AppendSwitchIfNotNull("--pdb:", pdbFile)
         // Platform
@@ -649,6 +657,18 @@ type public Fsc() as this =
         with get () = subsystemVersion
         and set (p) = subsystemVersion <- p
 
+    member _.Nullable
+        with get () =
+            match nullable with
+            | None -> ""
+            | Some true -> "enable"
+            | Some false -> "disable"
+        and set (p) =
+            match p with
+            | "enable" -> nullable <- Some true
+            | "disable" -> nullable <- Some false
+            | _ -> ()
+
     member _.HighEntropyVA
         with get () = highEntropyVA
         and set (p) = highEntropyVA <- p
diff --git a/src/FSharp.Build/Microsoft.FSharp.Targets b/src/FSharp.Build/Microsoft.FSharp.Targets
index 0ac058e30ba..7334f979086 100644
--- a/src/FSharp.Build/Microsoft.FSharp.Targets
+++ b/src/FSharp.Build/Microsoft.FSharp.Targets
@@ -412,7 +412,8 @@ this file.
               WarnOn="$(WarnOn)"
               Win32IconFile="$(ApplicationIcon)"
               Win32ManifestFile="$(Win32Manifest)"
-              Win32ResourceFile="$(Win32Resource)">
+              Win32ResourceFile="$(Win32Resource)"
+              Nullable="$(Nullable)">
           <Output TaskParameter="CommandLineArgs" ItemName="FscCommandLineArgs" />
         </Fsc>