diff --git a/src/mono/mono/mini/method-to-ir.c b/src/mono/mono/mini/method-to-ir.c
index c696cb634566a8..324b4ba778c023 100644
--- a/src/mono/mono/mini/method-to-ir.c
+++ b/src/mono/mono/mini/method-to-ir.c
@@ -7548,6 +7548,9 @@ mono_method_to_ir (MonoCompile *cfg, MonoMethod *method, MonoBasicBlock *start_b
 					if (cfg->compile_aot)
 						cfg->pinvoke_calli_signatures = g_slist_prepend_mempool (cfg->mempool, cfg->pinvoke_calli_signatures, fsig);
 
+					if (fsig->has_type_parameters)
+						GENERIC_SHARING_FAILURE (CEE_CALLI);
+
 					/* Call the wrapper that will do the GC transition instead */
 					MonoMethod *wrapper = mono_marshal_get_native_func_wrapper_indirect (method->klass, fsig, cfg->compile_aot);