diff --git a/eng/native/gen-buildsys.cmd b/eng/native/gen-buildsys.cmd
index b81ef55cbe49bb..4c50b42d0274cd 100644
--- a/eng/native/gen-buildsys.cmd
+++ b/eng/native/gen-buildsys.cmd
@@ -60,6 +60,7 @@ if /i "%__Arch%" == "wasm" (
         set __UseEmcmake=1
     )
     if /i "%__Os%" == "wasi" (
+        set "__repoRoot=!__repoRoot:\=/!"
         if "%WASI_SDK_PATH%" == "" (
             if not exist "%__repoRoot%\src\mono\wasi\wasi-sdk" (
                 echo Error: Should set WASI_SDK_PATH environment variable pointing to WASI SDK root.
@@ -72,7 +73,7 @@ if /i "%__Arch%" == "wasm" (
         set "WASI_SDK_PATH=!WASI_SDK_PATH:\=/!"
         if not "!WASI_SDK_PATH:~-1!" == "/" set "WASI_SDK_PATH=!WASI_SDK_PATH!/"
         set __CmakeGenerator=Ninja
-        set __ExtraCmakeParams=%__ExtraCmakeParams% -DCLR_CMAKE_TARGET_OS=wasi -DCLR_CMAKE_TARGET_ARCH=wasm "-DWASI_SDK_PREFIX=!WASI_SDK_PATH!" "-DCMAKE_TOOLCHAIN_FILE=!WASI_SDK_PATH!/share/cmake/wasi-sdk.cmake" "-DCMAKE_SYSROOT=!WASI_SDK_PATH!/share/wasi-sysroot"
+        set __ExtraCmakeParams=%__ExtraCmakeParams% -DCLR_CMAKE_TARGET_OS=wasi -DCLR_CMAKE_TARGET_ARCH=wasm "-DWASI_SDK_PREFIX=!WASI_SDK_PATH!" "-DCMAKE_TOOLCHAIN_FILE=!__repoRoot!/src/native/external/wasi-sdk-p2.cmake" "-DCMAKE_SYSROOT=!WASI_SDK_PATH!/share/wasip2-sysroot"
     )
 ) else (
     set __ExtraCmakeParams=%__ExtraCmakeParams%  "-DCMAKE_SYSTEM_VERSION=10.0"
diff --git a/eng/native/gen-buildsys.sh b/eng/native/gen-buildsys.sh
index 4c1ed0943c45ac..ba2d87a7f74645 100755
--- a/eng/native/gen-buildsys.sh
+++ b/eng/native/gen-buildsys.sh
@@ -4,6 +4,7 @@
 #
 
 scriptroot="$( cd -P "$( dirname "$0" )" && pwd )"
+reporoot="$(cd "$scriptroot"/../..; pwd -P)"
 
 if [[ "$#" -lt 4 ]]; then
   echo "Usage..."
@@ -97,7 +98,7 @@ if [[ "$host_arch" == "wasm" ]]; then
     if [[ "$target_os" == "browser" ]]; then
         cmake_command="emcmake $cmake_command"
     elif [[ "$target_os" == "wasi" ]]; then
-        true
+        cmake_extra_defines="$cmake_extra_defines -DCLR_CMAKE_TARGET_OS=wasi -DCLR_CMAKE_TARGET_ARCH=wasm -DWASI_SDK_PREFIX=$WASI_SDK_PATH -DCMAKE_TOOLCHAIN_FILE=$reporoot/src/native/external/wasi-sdk-p2.cmake" "-DCMAKE_SYSROOT=!WASI_SDK_PATH!/share/wasip2-sysroot"
     else
         echo "target_os was not specified"
         exit 1
diff --git a/src/mono/CMakeLists.txt b/src/mono/CMakeLists.txt
index ba41fa4d9a489f..3e964741a5dbeb 100644
--- a/src/mono/CMakeLists.txt
+++ b/src/mono/CMakeLists.txt
@@ -150,7 +150,7 @@ if(NOT AOT_TARGET_TRIPLE STREQUAL "")
   elseif(AOT_TARGET_TRIPLE STREQUAL "wasm32-unknown-none")
     set(TARGET_SYSTEM_NAME "emscripten")
     set(TARGET_ARCH "wasm")
-  elseif(AOT_TARGET_TRIPLE STREQUAL "wasm32-unknown-wasi")
+  elseif(AOT_TARGET_TRIPLE STREQUAL "wasm32-unknown-wasip2")
     set(TARGET_SYSTEM_NAME "wasi")
     set(TARGET_ARCH "wasm")
   elseif(AOT_TARGET_TRIPLE STREQUAL "x86_64-none-linux-android")
diff --git a/src/mono/Directory.Build.props b/src/mono/Directory.Build.props
index d97bf84a1da660..5ae32b4bdd225e 100644
--- a/src/mono/Directory.Build.props
+++ b/src/mono/Directory.Build.props
@@ -34,12 +34,9 @@
 
   <!-- Directory to provision and use WASI sdk if WASI_SDK_PATH env variable is not set -->
   <PropertyGroup Condition="'$(TargetsWasi)' == 'true'">
-    <!-- force download temmporarily https://github.com/dotnet/runtime/issues/101528
-    <WASI_SDK_PATH Condition="'$(WASI_SDK_PATH)' == ''">$([MSBuild]::NormalizeDirectory($(MSBuildThisFileDirectory), 'wasi', 'wasi-sdk'))</WASI_SDK_PATH>
-    -->
     <WASI_SDK_PATH>$([MSBuild]::NormalizeDirectory($(MSBuildThisFileDirectory), 'wasi', 'wasi-sdk'))</WASI_SDK_PATH>
     <WASI_SDK_PATH>$([MSBuild]::EnsureTrailingSlash('$(WASI_SDK_PATH)').Replace('\', '/'))</WASI_SDK_PATH>
-    <ShouldProvisionWasiSdk Condition="!Exists($(_ProvisionWasiSdkDir))">true</ShouldProvisionWasiSdk>
+    <ShouldProvisionWasiSdk Condition="!Exists($(WASI_SDK_PATH))">true</ShouldProvisionWasiSdk>
   </PropertyGroup>
 
   <PropertyGroup>
diff --git a/src/mono/mono.proj b/src/mono/mono.proj
index 14056eb3a7e24e..c671d48e85af9c 100644
--- a/src/mono/mono.proj
+++ b/src/mono/mono.proj
@@ -327,6 +327,11 @@ JS_ENGINES = [NODE_JS]
           Condition="'$(HostOS)' == 'windows'"
           WorkingDirectory="$(ArtifactsObjDir)"
           IgnoreStandardErrorWarningFormat="true" />
+
+    <Copy SourceFiles="$(MSBuildThisFileDirectory)/wasi/wasi-sdk/share/wasi-sysroot/include/wasm32-wasi-threads/pthread.h"
+          DestinationFiles="$(MSBuildThisFileDirectory)/wasi/wasi-sdk/share/wasi-sysroot/include/wasm32-wasip2/pthread.h"
+          />
+
   </Target>
 
   <Target Name="ValidateWasiSdk" Condition="'$(SkipMonoCrossJitConfigure)' != 'true'">
@@ -851,7 +856,7 @@ JS_ENGINES = [NODE_JS]
     <PropertyGroup Condition="'$(TargetsBrowser)' == 'true' or '$(TargetsWasi)' == 'true'">
       <MonoUseCrossTool>true</MonoUseCrossTool>
       <MonoAotAbi Condition="'$(TargetsBrowser)' == 'true'">wasm32-unknown-none</MonoAotAbi>
-      <MonoAotAbi Condition="'$(TargetsWasi)' == 'true'">wasm32-unknown-wasi</MonoAotAbi>
+      <MonoAotAbi Condition="'$(TargetsWasi)' == 'true'">wasm32-unknown-wasip2</MonoAotAbi>
       <MonoAotOffsetsFile>$(MonoObjCrossDir)offsets-wasm32-unknown-none.h</MonoAotOffsetsFile>
       <MonoLibClang Condition="$([MSBuild]::IsOSPlatform('OSX'))">$(MonoLLVMDir)/$(BuildArchitecture)/lib/libclang.dylib</MonoLibClang>
       <MonoLibClang Condition="$([MSBuild]::IsOSPlatform('Linux'))">$(MonoLLVMDir)/$(BuildArchitecture)/lib/libclang.so</MonoLibClang>
diff --git a/src/mono/mono/mini/mini-wasm.h b/src/mono/mono/mini/mini-wasm.h
index 95bafda3336c04..cef95c98ed4fe5 100644
--- a/src/mono/mono/mini/mini-wasm.h
+++ b/src/mono/mono/mini/mini-wasm.h
@@ -92,7 +92,7 @@ typedef struct {
 #define MONO_ARCH_HAVE_SDB_TRAMPOLINES 1
 #define MONO_ARCH_LLVM_TARGET_LAYOUT "e-m:e-p:32:32-i64:64-n32:64-S128"
 #ifdef TARGET_WASI
-#define MONO_ARCH_LLVM_TARGET_TRIPLE "wasm32-unknown-wasi"
+#define MONO_ARCH_LLVM_TARGET_TRIPLE "wasm32-unknown-wasip2"
 #else
 #define MONO_ARCH_LLVM_TARGET_TRIPLE "wasm32-unknown-emscripten"
 #endif
diff --git a/src/mono/wasi/provision.ps1 b/src/mono/wasi/provision.ps1
index ff336ef4bc22b5..1a6f40cb462de2 100644
--- a/src/mono/wasi/provision.ps1
+++ b/src/mono/wasi/provision.ps1
@@ -17,3 +17,11 @@ Invoke-WebRequest -Uri $WasiSdkUrl -OutFile ./wasi-sdk-$WasiSdkVersion.0-mingw.t
 tar --strip-components=1 -xzf ./wasi-sdk-$WasiSdkVersion.0-mingw.tar.gz -C $WasiSdkPath
 Copy-Item $WasiLocalPath/wasi-sdk-version.txt $WasiSdkPath/wasi-sdk-version.txt
 Remove-Item ./wasi-sdk-$WasiSdkVersion.0-mingw.tar.gz -fo
+
+# Temporary WASI-SDK 22 workaround #2: The version of `wasm-component-ld` that
+# ships with WASI-SDK 22 contains a
+# [bug](https://github.com/bytecodealliance/wasm-component-ld/issues/22) which
+# has been fixed in a v0.5.3 of that utility, so we upgrade it here.
+Invoke-WebRequest -Uri https://github.com/bytecodealliance/wasm-component-ld/releases/download/v0.5.3/wasm-component-ld-v0.5.3-x86_64-windows.zip -OutFile wasm-component-ld-v0.5.3-x86_64-windows.zip
+Expand-Archive -LiteralPath wasm-component-ld-v0.5.3-x86_64-windows.zip -DestinationPath .
+Copy-Item wasm-component-ld-v0.5.3-x86_64-windows/wasm-component-ld.exe $WasiSdkPath/bin
\ No newline at end of file
diff --git a/src/native/external/wasi-sdk-p2.cmake b/src/native/external/wasi-sdk-p2.cmake
new file mode 100644
index 00000000000000..263f20896e303d
--- /dev/null
+++ b/src/native/external/wasi-sdk-p2.cmake
@@ -0,0 +1,45 @@
+# TODO: WASI-SDK doesn't provide a CMake toolchain file for `wasm32-wasip2`, so
+# we must provide it ourselves.  Once
+# https://github.com/WebAssembly/wasi-sdk/pull/430 is merged and included in an
+# upcoming release, we'll be able to remove this file and use that instead.
+
+# Cmake toolchain description file for the Makefile
+
+# This is arbitrary, AFAIK, for now.
+cmake_minimum_required(VERSION 3.4.0)
+
+# Until Platform/WASI.cmake is upstream we need to inject the path to it
+# into CMAKE_MODULE_PATH.
+list(APPEND CMAKE_MODULE_PATH "${CMAKE_CURRENT_LIST_DIR}")
+
+set(CMAKE_SYSTEM_NAME WASI)
+set(CMAKE_SYSTEM_VERSION 1)
+set(CMAKE_SYSTEM_PROCESSOR wasm32)
+set(triple wasm32-wasip2)
+
+if(WIN32)
+	set(WASI_HOST_EXE_SUFFIX ".exe")
+else()
+	set(WASI_HOST_EXE_SUFFIX "")
+endif()
+
+# When building from source, WASI_SDK_PREFIX represents the generated directory
+if(NOT WASI_SDK_PREFIX)
+    set(WASI_SDK_PREFIX ${CMAKE_CURRENT_LIST_DIR}/../../)
+endif()
+
+set(CMAKE_C_COMPILER ${WASI_SDK_PREFIX}/bin/clang${WASI_HOST_EXE_SUFFIX})
+set(CMAKE_CXX_COMPILER ${WASI_SDK_PREFIX}/bin/clang++${WASI_HOST_EXE_SUFFIX})
+set(CMAKE_ASM_COMPILER ${WASI_SDK_PREFIX}/bin/clang${WASI_HOST_EXE_SUFFIX})
+set(CMAKE_AR ${WASI_SDK_PREFIX}/bin/llvm-ar${WASI_HOST_EXE_SUFFIX})
+set(CMAKE_RANLIB ${WASI_SDK_PREFIX}/bin/llvm-ranlib${WASI_HOST_EXE_SUFFIX})
+set(CMAKE_C_COMPILER_TARGET ${triple})
+set(CMAKE_CXX_COMPILER_TARGET ${triple})
+set(CMAKE_ASM_COMPILER_TARGET ${triple})
+
+# Don't look in the sysroot for executables to run during the build
+set(CMAKE_FIND_ROOT_PATH_MODE_PROGRAM NEVER)
+# Only look in the sysroot (not in the host paths) for the rest
+set(CMAKE_FIND_ROOT_PATH_MODE_LIBRARY ONLY)
+set(CMAKE_FIND_ROOT_PATH_MODE_INCLUDE ONLY)
+set(CMAKE_FIND_ROOT_PATH_MODE_PACKAGE ONLY)