diff --git a/src/coreclr/jit/hwintrinsiccodegenxarch.cpp b/src/coreclr/jit/hwintrinsiccodegenxarch.cpp
index fdf6e0b0058a06..cb6d1821e3f034 100644
--- a/src/coreclr/jit/hwintrinsiccodegenxarch.cpp
+++ b/src/coreclr/jit/hwintrinsiccodegenxarch.cpp
@@ -1090,18 +1090,12 @@ void CodeGen::genHWIntrinsic_R_R_RM_I(
 
     assert(targetReg != REG_NA);
 
-    if (op2->isContained() || op2->isUsedFromSpillTemp())
-    {
-        assert(HWIntrinsicInfo::SupportsContainment(node->GetHWIntrinsicId()));
-        assertIsContainableHWIntrinsicOp(compiler->m_pLowering, node, op2);
-    }
-
     if (ins == INS_insertps)
     {
-        if (op1Reg == REG_NA)
+        if (op1->isContained())
         {
             // insertps is special and can contain op1 when it is zero
-            assert(op1->isContained() && op1->IsVectorZero());
+            assert(op1->IsVectorZero());
             op1Reg = targetReg;
         }
 
@@ -1115,6 +1109,12 @@ void CodeGen::genHWIntrinsic_R_R_RM_I(
         }
     }
 
+    if (op2->isContained() || op2->isUsedFromSpillTemp())
+    {
+        assert(HWIntrinsicInfo::SupportsContainment(node->GetHWIntrinsicId()));
+        assertIsContainableHWIntrinsicOp(compiler->m_pLowering, node, op2);
+    }
+
     assert(op1Reg != REG_NA);
 
     bool isRMW = node->isRMWHWIntrinsic(compiler);
diff --git a/src/tests/JIT/Regression/JitBlue/Runtime_105467/Runtime_105467.cs b/src/tests/JIT/Regression/JitBlue/Runtime_105467/Runtime_105467.cs
new file mode 100644
index 00000000000000..909de7fc3e2640
--- /dev/null
+++ b/src/tests/JIT/Regression/JitBlue/Runtime_105467/Runtime_105467.cs
@@ -0,0 +1,35 @@
+// Licensed to the .NET Foundation under one or more agreements.
+// The .NET Foundation licenses this file to you under the MIT license.
+
+using System;
+using System.Runtime.CompilerServices;
+using System.Numerics;
+using System.Runtime.Intrinsics;
+using System.Runtime.Intrinsics.X86;
+using Xunit;
+
+// Generated by Fuzzlyn v1.7 on 2024-07-25 11:29:20
+// Run on X64 Windows
+// Seed: 17281006834984098297-vectort,vector128,vector256,x86aes,x86avx,x86avx2,x86bmi1,x86bmi1x64,x86bmi2,x86bmi2x64,x86fma,x86lzcnt,x86lzcntx64,x86pclmulqdq,x86popcnt,x86popcntx64,x86sse,x86ssex64,x86sse2,x86sse2x64,x86sse3,x86sse41,x86sse41x64,x86sse42,x86sse42x64,x86ssse3,x86x86base
+// Reduced from 159.4 KiB to 0.4 KiB in 00:00:57
+// Hits JIT assert in Release:
+// Assertion failed 'isContainable || supportsRegOptional' in 'Program:Main(Fuzzlyn.ExecutionServer.IRuntime)' during 'Generate code' (IL size 47; hash 0xade6b36b; FullOpts)
+//
+//     File: C:\dev\dotnet\runtime4\src\coreclr\jit\hwintrinsiccodegenxarch.cpp Line: 61
+//
+
+public class Runtime_105467
+{
+    public static Vector128<float>[] s_6 = new []{ Vector128<float>.Zero };
+
+    [Fact]
+    public static void TestEntryPoint()
+    {
+        if (Sse41.IsSupported)
+        {
+            var vr3 = s_6[0];
+            var vr4 = Vector128.Create<float>(0);
+            s_6[0] = Sse41.Insert(vr3, vr4, 254);
+        }
+    }
+}
diff --git a/src/tests/JIT/Regression/JitBlue/Runtime_105467/Runtime_105467.csproj b/src/tests/JIT/Regression/JitBlue/Runtime_105467/Runtime_105467.csproj
new file mode 100644
index 00000000000000..de6d5e08882e86
--- /dev/null
+++ b/src/tests/JIT/Regression/JitBlue/Runtime_105467/Runtime_105467.csproj
@@ -0,0 +1,8 @@
+<Project Sdk="Microsoft.NET.Sdk">
+  <PropertyGroup>
+    <Optimize>True</Optimize>
+  </PropertyGroup>
+  <ItemGroup>
+    <Compile Include="$(MSBuildProjectName).cs" />
+  </ItemGroup>
+</Project>