diff --git a/src/coreclr/jit/importercalls.cpp b/src/coreclr/jit/importercalls.cpp
index 3b065e4f40af58..4f4a2f6bacf61a 100644
--- a/src/coreclr/jit/importercalls.cpp
+++ b/src/coreclr/jit/importercalls.cpp
@@ -180,12 +180,6 @@ var_types Compiler::impImportCall(OPCODE                  opcode,
                 compInlineResult->NoteFatal(InlineObservation::CALLEE_HAS_MANAGED_VARARGS);
                 return TYP_UNDEF;
             }
-
-            if ((mflags & CORINFO_FLG_VIRTUAL) && (sig->sigInst.methInstCount != 0) && (opcode == CEE_CALLVIRT))
-            {
-                compInlineResult->NoteFatal(InlineObservation::CALLEE_IS_GENERIC_VIRTUAL);
-                return TYP_UNDEF;
-            }
         }
 
         clsHnd = pResolvedToken->hClass;
@@ -381,12 +375,6 @@ var_types Compiler::impImportCall(OPCODE                  opcode,
 
             case CORINFO_VIRTUALCALL_LDVIRTFTN:
             {
-                if (compIsForInlining())
-                {
-                    compInlineResult->NoteFatal(InlineObservation::CALLSITE_HAS_CALL_VIA_LDVIRTFTN);
-                    return TYP_UNDEF;
-                }
-
                 assert(!(mflags & CORINFO_FLG_STATIC)); // can't call a static method
                 assert(!(clsFlags & CORINFO_FLG_VALUECLASS));
                 // OK, We've been told to call via LDVIRTFTN, so just
diff --git a/src/coreclr/jit/inline.def b/src/coreclr/jit/inline.def
index 6ce57ccfeed7ac..b8bc674bce09a3 100644
--- a/src/coreclr/jit/inline.def
+++ b/src/coreclr/jit/inline.def
@@ -39,7 +39,6 @@ INLINE_OBSERVATION(HAS_NO_BODY,               bool,   "has no body",
 INLINE_OBSERVATION(HAS_NULL_FOR_LDELEM,       bool,   "has null pointer for ldelem",          FATAL,       CALLEE)
 INLINE_OBSERVATION(HAS_UNMANAGED_CALLCONV,    bool,   "has unmanaged calling convention",     FATAL,       CALLEE)
 INLINE_OBSERVATION(IS_ARRAY_METHOD,           bool,   "is array method",                      FATAL,       CALLEE)
-INLINE_OBSERVATION(IS_GENERIC_VIRTUAL,        bool,   "generic virtual",                      FATAL,       CALLEE)
 INLINE_OBSERVATION(IS_JIT_NOINLINE,           bool,   "noinline per JitNoinline",             FATAL,       CALLEE)
 INLINE_OBSERVATION(IS_NOINLINE,               bool,   "noinline per IL/cached result",        FATAL,       CALLEE)
 INLINE_OBSERVATION(IS_SYNCHRONIZED,           bool,   "is synchronized",                      FATAL,       CALLEE)
@@ -137,7 +136,6 @@ INLINE_OBSERVATION(COMPILATION_FAILURE,       bool,   "failed to compile",
 INLINE_OBSERVATION(EXPLICIT_TAIL_PREFIX,      bool,   "explicit tail prefix",                 FATAL,       CALLSITE)
 INLINE_OBSERVATION(EH_TABLE_FULL,             bool,   "callee has eh, eh table is full",      FATAL,       CALLSITE)
 INLINE_OBSERVATION(GENERIC_DICTIONARY_LOOKUP, bool,   "runtime dictionary lookup",            FATAL,       CALLSITE)
-INLINE_OBSERVATION(HAS_CALL_VIA_LDVIRTFTN,    bool,   "call via ldvirtftn",                   FATAL,       CALLSITE)
 INLINE_OBSERVATION(HAS_COMPLEX_HANDLE,        bool,   "complex handle access",                FATAL,       CALLSITE)
 INLINE_OBSERVATION(IMPLICIT_REC_TAIL_CALL,    bool,   "implicit recursive tail call",         FATAL,       CALLSITE)
 INLINE_OBSERVATION(IS_CALL_TO_HELPER,         bool,   "target is helper",                     FATAL,       CALLSITE)