diff --git a/src/libraries/tests.proj b/src/libraries/tests.proj
index 5641c763c36977..ffeb39af997abd 100644
--- a/src/libraries/tests.proj
+++ b/src/libraries/tests.proj
@@ -231,7 +231,6 @@
 
   <ItemGroup Condition="'$(TargetOS)' == 'android' and '$(RuntimeFlavor)' == 'CoreCLR' and '$(RunDisablediOSTests)' != 'true'">
     <!-- https://github.com/dotnet/runtime/issues/114951 -->
-    <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Runtime\tests\System.Globalization.Tests\Invariant\Invariant.Tests.csproj" />
     <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Net.Http\tests\FunctionalTests\System.Net.Http.Functional.Tests.csproj" />
     <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Diagnostics.DiagnosticSource\tests\TestWithConfigSwitches\System.Diagnostics.DiagnosticSource.Switches.Tests.csproj" />
     <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Reflection.MetadataLoadContext\tests\System.Reflection.MetadataLoadContext.Tests.csproj" />
diff --git a/src/mono/msbuild/android/build/AndroidBuild.targets b/src/mono/msbuild/android/build/AndroidBuild.targets
index 56dd94a5983986..886e99635a34c6 100644
--- a/src/mono/msbuild/android/build/AndroidBuild.targets
+++ b/src/mono/msbuild/android/build/AndroidBuild.targets
@@ -251,6 +251,7 @@
         ForceAOT="$(RunAOTCompilation)"
         ForceFullAOT="$(ForceFullAOT)"
         ForceInterpreter="$(MonoForceInterpreter)"
+        InvariantGlobalization="$(InvariantGlobalization)"
         IsLibraryMode="$(_IsLibraryMode)"
         MainLibraryFileName="$(MainLibraryFileName)"
         RuntimeHeaders="@(RuntimeHeaders)"
diff --git a/src/tasks/AndroidAppBuilder/AndroidAppBuilder.cs b/src/tasks/AndroidAppBuilder/AndroidAppBuilder.cs
index 006b746ef0d010..bf3d76bcb24626 100644
--- a/src/tasks/AndroidAppBuilder/AndroidAppBuilder.cs
+++ b/src/tasks/AndroidAppBuilder/AndroidAppBuilder.cs
@@ -108,6 +108,11 @@ public class AndroidAppBuilderTask : Task
 
     public bool ForceInterpreter { get; set; }
 
+    /// <summary>
+    /// Indicates whether we want to use invariant globalization mode.
+    /// </summary>
+    public bool InvariantGlobalization { get; set; }
+
     [Output]
     public string ApkBundlePath { get; set; } = ""!;
 
@@ -141,6 +146,7 @@ public override bool Execute()
         apkBuilder.NativeDependencies = NativeDependencies;
         apkBuilder.ExtraLinkerArguments = ExtraLinkerArguments;
         apkBuilder.RuntimeFlavor = RuntimeFlavor;
+        apkBuilder.InvariantGlobalization = InvariantGlobalization;
         (ApkBundlePath, ApkPackageId) = apkBuilder.BuildApk(RuntimeIdentifier, MainLibraryFileName, RuntimeHeaders);
 
         return true;
diff --git a/src/tasks/AndroidAppBuilder/ApkBuilder.cs b/src/tasks/AndroidAppBuilder/ApkBuilder.cs
index 21fd800c89681a..df0772393e73a8 100644
--- a/src/tasks/AndroidAppBuilder/ApkBuilder.cs
+++ b/src/tasks/AndroidAppBuilder/ApkBuilder.cs
@@ -424,6 +424,11 @@ public ApkBuilder(TaskLoggingHelper logger)
             envVariables += $"\t\tsetEnv(\"{name}\", \"{value}\");\n";
         }
 
+        if (InvariantGlobalization)
+        {
+            envVariables += $"\t\tsetEnv(\"DOTNET_SYSTEM_GLOBALIZATION_INVARIANT\", \"true\");\n";
+        }
+
         string jniLibraryName = (IsLibraryMode) ? ProjectName! :
             (StaticLinkedRuntime && IsCoreCLR) ? "monodroid" : "System.Security.Cryptography.Native.Android";
         string monoRunner = Utils.GetEmbeddedResource("MonoRunner.java")
diff --git a/src/tests/build.proj b/src/tests/build.proj
index 8499575b01c257..b1fd5ba3b72efb 100644
--- a/src/tests/build.proj
+++ b/src/tests/build.proj
@@ -264,6 +264,7 @@
         AppDir="$(BuildDir)"
         DiagnosticPorts="$(DiagnosticPorts)"
         ForceInterpreter="$(MonoInterp)"
+        InvariantGlobalization="$(InvariantGlobalization)"
         RuntimeHeaders="$(MicrosoftNetCoreAppRuntimePackDir)/native/include/mono-2.0"
         OutputDir="$(AppDir)"
         ProjectName="$(Category)"