diff --git a/src/mono/mono.proj b/src/mono/mono.proj
index 2cb4ba6ffec9f1..e0fa813eb20601 100644
--- a/src/mono/mono.proj
+++ b/src/mono/mono.proj
@@ -953,6 +953,14 @@ JS_ENGINES = [NODE_JS]
       <_MonoAOTCFLAGSOption>-DCMAKE_C_FLAGS=&quot;@(_MonoAOTCPPFLAGS, ' ') @(_MonoAOTCFLAGS, ' ')&quot;</_MonoAOTCFLAGSOption>
       <_MonoAOTCXXFLAGSOption>-DCMAKE_CXX_FLAGS=&quot;@(_MonoAOTCPPFLAGS, ' ') @(_MonoAOTCXXFLAGS, ' ')&quot;</_MonoAOTCXXFLAGSOption>
     </PropertyGroup>
+
+    <PropertyGroup>
+      <_PythonCmd Condition="'$(HostOS)' != 'windows'">python3</_PythonCmd>
+      <_PythonCmd Condition="'$(HostOS)' == 'windows'">python</_PythonCmd>
+      <!-- Use python from the transport pack on Browser/Wasi -->
+      <_PythonCmd Condition="'$(HostOS)' == 'windows' and ('$(TargetsBrowser)' == 'true' or '$(TargetsWasi)' == 'true')">$([MSBuild]::NormalizePath('$(PkgMicrosoft_NET_Runtime_Emscripten_3_1_56_Python_win-x64)', 'tools', 'python.exe'))</_PythonCmd>
+    </PropertyGroup>
+
     <ItemGroup>
       <MonoAOTCMakeArgs Include="-DAOT_TARGET_TRIPLE=$(MonoAotAbi)"/>
       <MonoAOTCMakeArgs Condition="'$(_MonoUseNinja)' == 'true'" Include="-G Ninja"/>
@@ -975,15 +983,12 @@ JS_ENGINES = [NODE_JS]
       <!-- rename exe -->
       <MonoAOTCMakeArgs Include="-DMONO_CROSS_COMPILE_EXECUTABLE_NAME=1" />
       <MonoAOTCMakeArgs Include="-DCLR_CMAKE_KEEP_NATIVE_SYMBOLS=true" Condition="'$(KeepNativeSymbols)' == 'true'" />
+      <MonoAOTCMakeArgs Condition="'$(HostOS)' == 'windows' and ('$(TargetsBrowser)' == 'true' or '$(TargetsWasi)' == 'true')" Include="-DPython_ROOT_DIR=$([System.IO.Directory]::GetParent('$(_PythonCmd)'))" />
     </ItemGroup>
 
     <PropertyGroup>
       <_MonoSkipInitCompiler Condition="'$(AotHostArchitecture)' != '$(BuildArchitecture)'">false</_MonoSkipInitCompiler>
       <_MonoSkipInitCompiler Condition="'$(CrossBuild)' == 'true'">false</_MonoSkipInitCompiler>
-      <_PythonCmd Condition="'$(HostOS)' != 'windows'">python3</_PythonCmd>
-      <_PythonCmd Condition="'$(HostOS)' == 'windows'">python</_PythonCmd>
-      <!-- Use python from the transport pack on Browser/Wasi -->
-      <_PythonCmd Condition="'$(HostOS)' == 'windows' and ('$(TargetsBrowser)' == 'true' or '$(TargetsWasi)' == 'true')">$([MSBuild]::NormalizePath('$(PkgMicrosoft_NET_Runtime_Emscripten_3_1_56_Python_win-x64)', 'tools', 'python.exe'))</_PythonCmd>
       <_MonoAotCrossOffsetsToolPath>$(MonoProjectRoot)mono\offsets\offsets-tool.py</_MonoAotCrossOffsetsToolPath>
       <_MonoAotCrossOffsetsCommand Condition="'$(MonoUseCrossTool)' == 'true'">$(_PythonCmd) $(_MonoAotCrossOffsetsToolPath) @(MonoAotCrossOffsetsToolParams, ' ')</_MonoAotCrossOffsetsCommand>
       <_MonoAotCMakeConfigureCommand>cmake @(MonoAOTCMakeArgs, ' ') $(MonoCMakeExtraArgs) &quot;$(MonoProjectRoot.TrimEnd('\/'))&quot;</_MonoAotCMakeConfigureCommand>
diff --git a/src/mono/mono/mini/CMakeLists.txt b/src/mono/mono/mini/CMakeLists.txt
index a2b3bdae9a72c0..23b8d15bf708f1 100644
--- a/src/mono/mono/mini/CMakeLists.txt
+++ b/src/mono/mono/mini/CMakeLists.txt
@@ -4,7 +4,7 @@ if(ENABLE_LLVM OR ENABLE_LLVM_RUNTIME OR HOST_BROWSER)
   enable_language(CXX)
 endif()
 
-include(FindPython3)
+include(FindPython)
 
 include_directories(
   ${PROJECT_BINARY_DIR}/
@@ -494,60 +494,60 @@ if(HOST_BROWSER OR HOST_WASI OR TARGET_WASM)
   install(TARGETS mono-wasm-nosimd LIBRARY)
 endif()
 
-find_package(Python3 COMPONENTS Interpreter)
+find_package(Python COMPONENTS Interpreter)
 
 add_custom_command(
   OUTPUT ${CMAKE_CURRENT_BINARY_DIR}/cpu-amd64.h
-  COMMAND ${Python3_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_AMD64 ${CMAKE_CURRENT_SOURCE_DIR} cpu-amd64.h amd64_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-amd64.mdesc
+  COMMAND ${Python_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_AMD64 ${CMAKE_CURRENT_SOURCE_DIR} cpu-amd64.h amd64_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-amd64.mdesc
   DEPENDS ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py mini-ops.h ${CMAKE_CURRENT_SOURCE_DIR}/cpu-amd64.mdesc
   VERBATIM
 )
 
 add_custom_command(
   OUTPUT ${CMAKE_CURRENT_BINARY_DIR}/cpu-x86.h
-  COMMAND ${Python3_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_X86 ${CMAKE_CURRENT_SOURCE_DIR} cpu-x86.h x86_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-x86.mdesc
+  COMMAND ${Python_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_X86 ${CMAKE_CURRENT_SOURCE_DIR} cpu-x86.h x86_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-x86.mdesc
   DEPENDS ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py mini-ops.h ${CMAKE_CURRENT_SOURCE_DIR}/cpu-x86.mdesc
   VERBATIM
 )
 
 add_custom_command(
   OUTPUT ${CMAKE_CURRENT_BINARY_DIR}/cpu-arm64.h
-  COMMAND ${Python3_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_ARM64 ${CMAKE_CURRENT_SOURCE_DIR} cpu-arm64.h arm64_cpu_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-arm64.mdesc
+  COMMAND ${Python_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_ARM64 ${CMAKE_CURRENT_SOURCE_DIR} cpu-arm64.h arm64_cpu_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-arm64.mdesc
   DEPENDS ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py mini-ops.h ${CMAKE_CURRENT_SOURCE_DIR}/cpu-arm64.mdesc
   VERBATIM
 )
 
 add_custom_command(
   OUTPUT ${CMAKE_CURRENT_BINARY_DIR}/cpu-arm.h
-  COMMAND ${Python3_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_ARM ${CMAKE_CURRENT_SOURCE_DIR} cpu-arm.h arm_cpu_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-arm.mdesc
+  COMMAND ${Python_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_ARM ${CMAKE_CURRENT_SOURCE_DIR} cpu-arm.h arm_cpu_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-arm.mdesc
   DEPENDS ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py mini-ops.h ${CMAKE_CURRENT_SOURCE_DIR}/cpu-arm.mdesc
   VERBATIM
 )
 
 add_custom_command(
   OUTPUT ${CMAKE_CURRENT_BINARY_DIR}/cpu-riscv64.h
-  COMMAND ${Python3_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_RISCV64 ${CMAKE_CURRENT_SOURCE_DIR} cpu-riscv64.h riscv64_cpu_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-riscv64.mdesc
+  COMMAND ${Python_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_RISCV64 ${CMAKE_CURRENT_SOURCE_DIR} cpu-riscv64.h riscv64_cpu_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-riscv64.mdesc
   DEPENDS ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py mini-ops.h ${CMAKE_CURRENT_SOURCE_DIR}/cpu-riscv64.mdesc
   VERBATIM
 )
 
 add_custom_command(
   OUTPUT ${CMAKE_CURRENT_BINARY_DIR}/cpu-s390x.h
-  COMMAND ${Python3_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_S390X ${CMAKE_CURRENT_SOURCE_DIR} cpu-s390x.h s390x_cpu_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-s390x.mdesc
+  COMMAND ${Python_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_S390X ${CMAKE_CURRENT_SOURCE_DIR} cpu-s390x.h s390x_cpu_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-s390x.mdesc
   DEPENDS ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py mini-ops.h ${CMAKE_CURRENT_SOURCE_DIR}/cpu-s390x.mdesc
   VERBATIM
 )
 
 add_custom_command(
   OUTPUT ${CMAKE_CURRENT_BINARY_DIR}/cpu-wasm.h
-  COMMAND ${Python3_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_WASM ${CMAKE_CURRENT_SOURCE_DIR} cpu-wasm.h wasm_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-wasm.mdesc
+  COMMAND ${Python_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_WASM ${CMAKE_CURRENT_SOURCE_DIR} cpu-wasm.h wasm_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-wasm.mdesc
   DEPENDS ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py mini-ops.h ${CMAKE_CURRENT_SOURCE_DIR}/cpu-wasm.mdesc
   VERBATIM
 )
 
 add_custom_command(
   OUTPUT ${CMAKE_CURRENT_BINARY_DIR}/cpu-ppc64.h
-  COMMAND ${Python3_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_POWERPC64 ${CMAKE_CURRENT_SOURCE_DIR} cpu-ppc64.h ppc64_cpu_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-ppc64.mdesc
+  COMMAND ${Python_EXECUTABLE} ${CMAKE_CURRENT_SOURCE_DIR}/genmdesc.py TARGET_POWERPC64 ${CMAKE_CURRENT_SOURCE_DIR} cpu-ppc64.h ppc64_cpu_desc ${CMAKE_CURRENT_SOURCE_DIR}/cpu-ppc64.mdesc
   VERBATIM
 )