diff --git a/src/libraries/System.Net.Sockets/tests/FunctionalTests/SocketOptionNameTest.cs b/src/libraries/System.Net.Sockets/tests/FunctionalTests/SocketOptionNameTest.cs
index 2d7139a05803cb..26752dd31f5dcb 100644
--- a/src/libraries/System.Net.Sockets/tests/FunctionalTests/SocketOptionNameTest.cs
+++ b/src/libraries/System.Net.Sockets/tests/FunctionalTests/SocketOptionNameTest.cs
@@ -67,7 +67,6 @@ public void MulticastOption_CreateSocketSetGetOption_GroupAndInterfaceIndex_SetS
 
         [ConditionalFact(typeof(PlatformDetection), nameof(PlatformDetection.IsNotWindowsNanoNorServerCore))] // Skip on Nano: https://github.com/dotnet/runtime/issues/26286
         [ActiveIssue("https://github.com/dotnet/runtime/issues/104547", typeof(PlatformDetection), nameof(PlatformDetection.IsQemuLinux))]
-        [ActiveIssue("https://github.com/dotnet/runtime/issues/113827", typeof(PlatformDetection), nameof(PlatformDetection.IsAppleMobile))]
         public async Task MulticastInterface_Set_AnyInterface_Succeeds()
         {
             // On all platforms, index 0 means "any interface"
diff --git a/src/native/libs/Common/pal_config.h.in b/src/native/libs/Common/pal_config.h.in
index 4439e8cebfeaa4..d789d0e2f5d807 100644
--- a/src/native/libs/Common/pal_config.h.in
+++ b/src/native/libs/Common/pal_config.h.in
@@ -67,6 +67,7 @@
 #cmakedefine01 HAVE_SUPPORT_FOR_DUAL_MODE_IPV4_PACKET_INFO
 #cmakedefine01 HAVE_IN_PKTINFO
 #cmakedefine01 HAVE_IP_MREQN
+#cmakedefine01 HAVE_IP_MULTICAST_IFINDEX
 #cmakedefine01 HAVE_NETINET_TCP_VAR_H
 #cmakedefine01 HAVE_NETINET_UDP_VAR_H
 #cmakedefine01 HAVE_NETINET_IP_VAR_H
diff --git a/src/native/libs/System.Native/pal_networking.c b/src/native/libs/System.Native/pal_networking.c
index cae1285e7e74e4..0ba5b87ebef1f7 100644
--- a/src/native/libs/System.Native/pal_networking.c
+++ b/src/native/libs/System.Native/pal_networking.c
@@ -1119,6 +1119,7 @@ int32_t SystemNative_GetIPv4MulticastOption(intptr_t socket, int32_t multicastOp
     return Error_SUCCESS;
 }
 
+
 int32_t SystemNative_SetIPv4MulticastOption(intptr_t socket, int32_t multicastOption, IPv4MulticastOption* option)
 {
     if (option == NULL)
@@ -1134,6 +1135,16 @@ int32_t SystemNative_SetIPv4MulticastOption(intptr_t socket, int32_t multicastOp
         return Error_EINVAL;
     }
 
+#if HAVE_IP_MULTICAST_IFINDEX
+    // Use IP_MULTICAST_IFINDEX when available for interface index specification
+    if (optionName == SocketOptionName_SO_IP_MULTICAST_IF)
+    {
+        uint32_t ifindex = (uint32_t)option->InterfaceIndex;
+        int err = setsockopt(fd, IPPROTO_IP, IP_MULTICAST_IFINDEX, &ifindex, sizeof(ifindex));
+        return err == 0 ? Error_SUCCESS : SystemNative_ConvertErrorPlatformToPal(errno);
+    }
+#endif
+
 #if HAVE_IP_MREQN
     struct ip_mreqn opt;
     memset(&opt, 0, sizeof(struct ip_mreqn));
diff --git a/src/native/libs/configure.cmake b/src/native/libs/configure.cmake
index 477f9f1f14a037..7a511c559585f8 100644
--- a/src/native/libs/configure.cmake
+++ b/src/native/libs/configure.cmake
@@ -82,6 +82,18 @@ check_c_source_compiles(
     "
     HAVE_IP_MREQN)
 
+check_c_source_compiles(
+    "
+    #include <sys/socket.h>
+    #include <${SOCKET_INCLUDES}>
+    int main(void)
+    {
+        int opt = IP_MULTICAST_IFINDEX;
+        return 0;
+    }
+    "
+    HAVE_IP_MULTICAST_IFINDEX)
+
 # /in_pktinfo
 
 check_c_source_compiles(