diff --git a/src/mono/mono/utils/mono-codeman.c b/src/mono/mono/utils/mono-codeman.c
index 26f8715c61dd0b..c655d04c8ccbea 100644
--- a/src/mono/mono/utils/mono-codeman.c
+++ b/src/mono/mono/utils/mono-codeman.c
@@ -735,12 +735,10 @@ mono_codeman_enable_write (void)
 	if (codeman_no_exec)
 		return;
 #ifdef HAVE_PTHREAD_JIT_WRITE_PROTECT_NP
-	if (__builtin_available (macOS 11, *)) {
-		int level = GPOINTER_TO_INT (mono_native_tls_get_value (write_level_tls_id));
-		level ++;
-		mono_native_tls_set_value (write_level_tls_id, GINT_TO_POINTER (level));
-		pthread_jit_write_protect_np (0);
-	}
+	int level = GPOINTER_TO_INT (mono_native_tls_get_value (write_level_tls_id));
+	level ++;
+	mono_native_tls_set_value (write_level_tls_id, GINT_TO_POINTER (level));
+	pthread_jit_write_protect_np (0);
 #elif defined(HOST_MACCAT) && defined(__aarch64__)
 	/* JITing in Catalyst apps is not allowed on Apple Silicon, so assume if we're here we don't really have executable pages. */
 #endif
@@ -758,14 +756,12 @@ mono_codeman_disable_write (void)
 	if (codeman_no_exec)
 		return;
 #ifdef HAVE_PTHREAD_JIT_WRITE_PROTECT_NP
-	if (__builtin_available (macOS 11, *)) {
-		int level = GPOINTER_TO_INT (mono_native_tls_get_value (write_level_tls_id));
-		g_assert (level);
-		level --;
-		mono_native_tls_set_value (write_level_tls_id, GINT_TO_POINTER (level));
-		if (level == 0)
-			pthread_jit_write_protect_np (1);
-	}
+	int level = GPOINTER_TO_INT (mono_native_tls_get_value (write_level_tls_id));
+	g_assert (level);
+	level --;
+	mono_native_tls_set_value (write_level_tls_id, GINT_TO_POINTER (level));
+	if (level == 0)
+		pthread_jit_write_protect_np (1);
 #elif defined(HOST_MACCAT) && defined(__aarch64__)
 	/* JITing in Catalyst apps is not allowed on Apple Silicon, so assume if we're here we don't really have executable pages */
 #endif
diff --git a/src/mono/mono/utils/mono-mmap.c b/src/mono/mono/utils/mono-mmap.c
index 09af6f8994b942..fe7db3bbaf3b8a 100644
--- a/src/mono/mono/utils/mono-mmap.c
+++ b/src/mono/mono/utils/mono-mmap.c
@@ -285,9 +285,7 @@ mono_valloc (void *addr, size_t length, int flags, MonoMemAccountType type)
 			mflags |= MAP_JIT;
 #if defined(HOST_ARM64) && !defined(HOST_MACCAT)
 		/* Patching code on apple silicon seems to cause random crashes without this flag */
-		/* No __builtin_available in old versions of Xcode that could be building Mono on x86 or amd64 */
-		if (__builtin_available (macOS 11, *))
-			mflags |= MAP_JIT;
+		mflags |= MAP_JIT;
 #endif
 	}
 #endif
diff --git a/src/native/libs/System.Security.Cryptography.Native.Apple/pal_ecc.c b/src/native/libs/System.Security.Cryptography.Native.Apple/pal_ecc.c
index dc5f195ab24226..88c4832ef30736 100644
--- a/src/native/libs/System.Security.Cryptography.Native.Apple/pal_ecc.c
+++ b/src/native/libs/System.Security.Cryptography.Native.Apple/pal_ecc.c
@@ -24,10 +24,7 @@ int32_t AppleCryptoNative_EccGenerateKey(int32_t keySizeBits,
     {
         CFDictionaryAddValue(attributes, kSecAttrKeyType, kSecAttrKeyTypeEC);
         CFDictionaryAddValue(attributes, kSecAttrKeySizeInBits, cfKeySizeValue);
-        if (__builtin_available(macOS 10.15, iOS 13, tvOS 13, *))
-        {
-            CFDictionaryAddValue(attributes, kSecUseDataProtectionKeychain, kCFBooleanTrue);
-        }
+        CFDictionaryAddValue(attributes, kSecUseDataProtectionKeychain, kCFBooleanTrue);
 
         *pPrivateKey = SecKeyCreateRandomKey(attributes, pErrorOut);
         if (*pPrivateKey != NULL)
diff --git a/src/native/libs/System.Security.Cryptography.Native.Apple/pal_rsa.c b/src/native/libs/System.Security.Cryptography.Native.Apple/pal_rsa.c
index 1746828d5b0d7d..fa76a4323225e5 100644
--- a/src/native/libs/System.Security.Cryptography.Native.Apple/pal_rsa.c
+++ b/src/native/libs/System.Security.Cryptography.Native.Apple/pal_rsa.c
@@ -26,10 +26,7 @@ int32_t AppleCryptoNative_RsaGenerateKey(int32_t keySizeBits,
     {
         CFDictionaryAddValue(attributes, kSecAttrKeyType, kSecAttrKeyTypeRSA);
         CFDictionaryAddValue(attributes, kSecAttrKeySizeInBits, cfKeySizeValue);
-        if (__builtin_available(macOS 10.15, iOS 13, tvOS 13, *))
-        {
-            CFDictionaryAddValue(attributes, kSecUseDataProtectionKeychain, kCFBooleanTrue);
-        }
+        CFDictionaryAddValue(attributes, kSecUseDataProtectionKeychain, kCFBooleanTrue);
 
         *pPrivateKey = SecKeyCreateRandomKey(attributes, pErrorOut);
         if (*pPrivateKey != NULL)
diff --git a/src/native/libs/System.Security.Cryptography.Native.Apple/pal_sec.c b/src/native/libs/System.Security.Cryptography.Native.Apple/pal_sec.c
index 07cc20d1724f20..8e48ff2ea279a5 100644
--- a/src/native/libs/System.Security.Cryptography.Native.Apple/pal_sec.c
+++ b/src/native/libs/System.Security.Cryptography.Native.Apple/pal_sec.c
@@ -5,10 +5,5 @@
 
 CFStringRef AppleCryptoNative_SecCopyErrorMessageString(OSStatus osStatus)
 {
-    if (__builtin_available(iOS 11.3, tvOS 11.3, *))
-    {
-        return SecCopyErrorMessageString(osStatus, NULL);
-    }
-
-    return CFStringCreateWithFormat(NULL, NULL, CFSTR("OSStatus %d"), (int)osStatus);
+    return SecCopyErrorMessageString(osStatus, NULL);
 }
diff --git a/src/native/minipal/memorybarrierprocesswide.c b/src/native/minipal/memorybarrierprocesswide.c
index 7582332f86c9e9..6a9704c9920a98 100644
--- a/src/native/minipal/memorybarrierprocesswide.c
+++ b/src/native/minipal/memorybarrierprocesswide.c
@@ -166,27 +166,9 @@ void minipal_memory_barrier_process_wide(void)
     // Iterate through each of the threads in the list.
     for (mach_msg_type_number_t i = 0; i < cThreads; i++)
     {
-        if (__builtin_available (macOS 10.14, iOS 12, tvOS 9, *))
-        {
-            // Request the threads pointer values to force the thread to emit a memory barrier
-            size_t registers = 128;
-            machret = thread_get_register_pointer_values(pThreads[i], &sp, &registers, registerValues);
-        }
-        else
-        {
-            // fallback implementation for older OS versions
-#if defined(HOST_AMD64)
-            x86_thread_state64_t threadState;
-            mach_msg_type_number_t count = x86_THREAD_STATE64_COUNT;
-            machret = thread_get_state(pThreads[i], x86_THREAD_STATE64, (thread_state_t)&threadState, &count);
-#elif defined(HOST_ARM64)
-            arm_thread_state64_t threadState;
-            mach_msg_type_number_t count = ARM_THREAD_STATE64_COUNT;
-            machret = thread_get_state(pThreads[i], ARM_THREAD_STATE64, (thread_state_t)&threadState, &count);
-#else
-            #error Unexpected architecture
-#endif
-        }
+        // Request the threads pointer values to force the thread to emit a memory barrier
+        size_t registers = 128;
+        machret = thread_get_register_pointer_values(pThreads[i], &sp, &registers, registerValues);
 
         if (machret == KERN_INSUFFICIENT_BUFFER_SIZE)
         {