diff --git a/extensions/resteasy-classic/resteasy-server-common/deployment/src/main/java/io/quarkus/resteasy/server/common/deployment/ResteasyServerCommonProcessor.java b/extensions/resteasy-classic/resteasy-server-common/deployment/src/main/java/io/quarkus/resteasy/server/common/deployment/ResteasyServerCommonProcessor.java
index ed6605aa3fbeb..31af96b46ca9e 100644
--- a/extensions/resteasy-classic/resteasy-server-common/deployment/src/main/java/io/quarkus/resteasy/server/common/deployment/ResteasyServerCommonProcessor.java
+++ b/extensions/resteasy-classic/resteasy-server-common/deployment/src/main/java/io/quarkus/resteasy/server/common/deployment/ResteasyServerCommonProcessor.java
@@ -240,7 +240,9 @@ public void build(
             jaxrsProvidersToRegisterBuildItem = getFilteredJaxrsProvidersToRegisterBuildItem(
                     jaxrsProvidersToRegisterBuildItem, allowedClasses, excludedClasses);
 
-            Collection<ClassInfo> knownApplications = index.getAllKnownSubclasses(ResteasyDotNames.APPLICATION);
+            Collection<ClassInfo> knownApplications = index.getAllKnownSubclasses(ResteasyDotNames.APPLICATION).stream()
+                    .filter(ci -> !ci.isAbstract()).collect(
+                            Collectors.toSet());
             // getAllowedClasses throws an Exception if multiple Applications are found, so we should only get 1
             if (knownApplications.size() == 1) {
                 appClass = knownApplications.iterator().next().name().toString();
diff --git a/extensions/resteasy-classic/resteasy/deployment/src/test/java/io/quarkus/resteasy/test/root/ApplicationTest.java b/extensions/resteasy-classic/resteasy/deployment/src/test/java/io/quarkus/resteasy/test/root/ApplicationTest.java
index eb5c2ad1879d0..22646dea2e296 100644
--- a/extensions/resteasy-classic/resteasy/deployment/src/test/java/io/quarkus/resteasy/test/root/ApplicationTest.java
+++ b/extensions/resteasy-classic/resteasy/deployment/src/test/java/io/quarkus/resteasy/test/root/ApplicationTest.java
@@ -42,7 +42,7 @@ class ApplicationTest {
                             ResponseFilter1.class, ResponseFilter2.class,
                             ResponseFilter3.class, ResponseFilter4.class, ResponseFilter5.class, ResponseFilter6.class,
                             Feature1.class, Feature2.class, DynamicFeature1.class, DynamicFeature2.class,
-                            ExceptionMapper1.class, ExceptionMapper2.class, AppTest.class));
+                            ExceptionMapper1.class, ExceptionMapper2.class, AppTest.class, AppTest2.class));
 
     @DisplayName("Should access to ok of resource 1 and provide a response with the expected headers")
     @Test
@@ -309,4 +309,8 @@ public Set<Object> getSingletons() {
                             new ResponseFilter1(), new DynamicFeature1()));
         }
     }
+
+    public static abstract class AppTest2 extends Application {
+
+    }
 }