diff --git a/x-pack/plugins/security_solution/cypress/integration/timeline_local_storage.spec.ts b/x-pack/plugins/security_solution/cypress/integration/timeline_local_storage.spec.ts
index 383ebe2220585..2fb265c55e3ad 100644
--- a/x-pack/plugins/security_solution/cypress/integration/timeline_local_storage.spec.ts
+++ b/x-pack/plugins/security_solution/cypress/integration/timeline_local_storage.spec.ts
@@ -13,7 +13,8 @@ import { TABLE_COLUMN_EVENTS_MESSAGE } from '../screens/hosts/external_events';
 import { waitsForEventsToBeLoaded, openEventsViewerFieldsBrowser } from '../tasks/hosts/events';
 import { removeColumn, resetFields } from '../tasks/timeline';
 
-describe('persistent timeline', () => {
+// FLAKY: https://github.com/elastic/kibana/issues/72339
+describe.skip('persistent timeline', () => {
   before(() => {
     loginAndWaitForPage(HOSTS_URL);
     openEvents();