diff --git a/src/plugins/kibana_usage_collection/server/collectors/management/schema.ts b/src/plugins/kibana_usage_collection/server/collectors/management/schema.ts
index e5ddfbe4dd037..6b3db9460eb7c 100644
--- a/src/plugins/kibana_usage_collection/server/collectors/management/schema.ts
+++ b/src/plugins/kibana_usage_collection/server/collectors/management/schema.ts
@@ -22,6 +22,10 @@ export const stackManagementSchema: MakeSchemaFrom<UsageStats> = {
       _meta: { description: 'Non-default value of setting.' },
     },
   },
+  'securitySolution:maxUnassociatedNotes': {
+    type: 'integer',
+    _meta: { description: 'The maximum number of allowed unassociated notes' },
+  },
   'securitySolution:defaultThreatIndex': {
     type: 'keyword',
     _meta: { description: 'Default value of the setting was changed.' },
diff --git a/src/plugins/kibana_usage_collection/server/collectors/management/types.ts b/src/plugins/kibana_usage_collection/server/collectors/management/types.ts
index 2acb487e7ed08..92076ebc302e2 100644
--- a/src/plugins/kibana_usage_collection/server/collectors/management/types.ts
+++ b/src/plugins/kibana_usage_collection/server/collectors/management/types.ts
@@ -183,5 +183,6 @@ export interface UsageStats {
   'aiAssistant:preferredAIAssistantType': string;
   'observability:profilingFetchTopNFunctionsFromStacktraces': boolean;
   'securitySolution:excludedDataTiersForRuleExecution': string[];
+  'securitySolution:maxUnassociatedNotes': number;
   'observability:searchExcludedDataTiers': string[];
 }
diff --git a/src/plugins/telemetry/schema/oss_plugins.json b/src/plugins/telemetry/schema/oss_plugins.json
index 616a037fbd5d1..a3e46f5684135 100644
--- a/src/plugins/telemetry/schema/oss_plugins.json
+++ b/src/plugins/telemetry/schema/oss_plugins.json
@@ -9888,6 +9888,12 @@
             }
           }
         },
+        "securitySolution:maxUnassociatedNotes": {
+          "type": "integer",
+          "_meta": {
+            "description": "The maximum number of allowed unassociated notes"
+          }
+        },
         "securitySolution:defaultThreatIndex": {
           "type": "keyword",
           "_meta": {
@@ -10050,7 +10056,7 @@
             "description": "Non-default value of setting."
           }
         },
-        "securitySolution:enableVisualizationsInFlyout":{
+        "securitySolution:enableVisualizationsInFlyout": {
           "type": "boolean",
           "_meta": {
             "description": "Non-default value of setting."
diff --git a/x-pack/plugins/security_solution/common/constants.ts b/x-pack/plugins/security_solution/common/constants.ts
index 35f2b8ae177c0..e7bb823c04ec8 100644
--- a/x-pack/plugins/security_solution/common/constants.ts
+++ b/x-pack/plugins/security_solution/common/constants.ts
@@ -71,6 +71,7 @@ export const SECURITY_TAG_NAME = 'Security Solution' as const;
 export const SECURITY_TAG_DESCRIPTION = 'Security Solution auto-generated tag' as const;
 export const DEFAULT_SPACE_ID = 'default' as const;
 export const DEFAULT_RELATIVE_DATE_THRESHOLD = 24 as const;
+export const DEFAULT_MAX_UNASSOCIATED_NOTES = 1000 as const;
 
 // Document path where threat indicator fields are expected. Fields are used
 // to enrich signals, and are copied to threat.enrichments.
@@ -200,6 +201,9 @@ export const ENABLE_ASSET_CRITICALITY_SETTING = 'securitySolution:enableAssetCri
 export const EXCLUDED_DATA_TIERS_FOR_RULE_EXECUTION =
   'securitySolution:excludedDataTiersForRuleExecution' as const;
 
+/** This Kibana Advances setting allows users to define the maximum amount of unassociated notes (notes without a `timelineId`) */
+export const MAX_UNASSOCIATED_NOTES = 'securitySolution:maxUnassociatedNotes' as const;
+
 /** This Kibana Advanced Setting allows users to enable/disable the Visualizations in Flyout feature */
 export const ENABLE_VISUALIZATIONS_IN_FLYOUT_SETTING =
   'securitySolution:enableVisualizationsInFlyout' as const;
diff --git a/x-pack/plugins/security_solution/public/notes/api/api.test.ts b/x-pack/plugins/security_solution/public/notes/api/api.test.ts
new file mode 100644
index 0000000000000..bc53b7bd78ac5
--- /dev/null
+++ b/x-pack/plugins/security_solution/public/notes/api/api.test.ts
@@ -0,0 +1,53 @@
+/*
+ * Copyright Elasticsearch B.V. and/or licensed to Elasticsearch B.V. under one
+ * or more contributor license agreements. Licensed under the Elastic License
+ * 2.0; you may not use this file except in compliance with the Elastic License
+ * 2.0.
+ */
+import type { PersistNoteRouteResponse } from '../../../common/api/timeline';
+import { KibanaServices } from '../../common/lib/kibana';
+import * as api from './api';
+
+jest.mock('../../common/lib/kibana', () => {
+  return {
+    KibanaServices: {
+      get: jest.fn(),
+    },
+  };
+});
+
+describe('Notes API client', () => {
+  beforeAll(() => {
+    jest.resetAllMocks();
+  });
+  describe('create note', () => {
+    it('should throw an error when a response code other than 200 is returned', async () => {
+      const errorResponse: PersistNoteRouteResponse = {
+        data: {
+          persistNote: {
+            code: 500,
+            message: 'Internal server error',
+            note: {
+              timelineId: '1',
+              noteId: '2',
+              version: '3',
+            },
+          },
+        },
+      };
+      (KibanaServices.get as jest.Mock).mockReturnValue({
+        http: {
+          patch: jest.fn().mockReturnValue(errorResponse),
+        },
+      });
+
+      expect(async () =>
+        api.createNote({
+          note: {
+            timelineId: '1',
+          },
+        })
+      ).rejects.toThrow();
+    });
+  });
+});
diff --git a/x-pack/plugins/security_solution/public/notes/api/api.ts b/x-pack/plugins/security_solution/public/notes/api/api.ts
index eb25eed9f2816..4bda803950b84 100644
--- a/x-pack/plugins/security_solution/public/notes/api/api.ts
+++ b/x-pack/plugins/security_solution/public/notes/api/api.ts
@@ -5,7 +5,12 @@
  * 2.0.
  */
 
-import type { BareNote, Note } from '../../../common/api/timeline';
+import type {
+  BareNote,
+  DeleteNoteResponse,
+  GetNotesResponse,
+  PersistNoteRouteResponse,
+} from '../../../common/api/timeline';
 import { KibanaServices } from '../../common/lib/kibana';
 import { NOTE_URL } from '../../../common/constants';
 
@@ -16,16 +21,18 @@ import { NOTE_URL } from '../../../common/constants';
  */
 export const createNote = async ({ note }: { note: BareNote }) => {
   try {
-    const response = await KibanaServices.get().http.patch<{
-      data: { persistNote: { code: number; message: string; note: Note } };
-    }>(NOTE_URL, {
+    const response = await KibanaServices.get().http.patch<PersistNoteRouteResponse>(NOTE_URL, {
       method: 'PATCH',
       body: JSON.stringify({ note }),
       version: '2023-10-31',
     });
-    return response.data.persistNote.note;
+    const noteResponse = response.data.persistNote;
+    if (noteResponse.code !== 200) {
+      throw new Error(noteResponse.message);
+    }
+    return noteResponse.note;
   } catch (err) {
-    throw new Error(`Failed to stringify query: ${JSON.stringify(err)}`);
+    throw new Error(('message' in err && err.message) || 'Request failed');
   }
 };
 
@@ -44,20 +51,17 @@ export const fetchNotes = async ({
   filter: string;
   search: string;
 }) => {
-  const response = await KibanaServices.get().http.get<{ totalCount: number; notes: Note[] }>(
-    NOTE_URL,
-    {
-      query: {
-        page,
-        perPage,
-        sortField,
-        sortOrder,
-        filter,
-        search,
-      },
-      version: '2023-10-31',
-    }
-  );
+  const response = await KibanaServices.get().http.get<GetNotesResponse>(NOTE_URL, {
+    query: {
+      page,
+      perPage,
+      sortField,
+      sortOrder,
+      filter,
+      search,
+    },
+    version: '2023-10-31',
+  });
   return response;
 };
 
@@ -65,13 +69,10 @@ export const fetchNotes = async ({
  * Fetches all the notes for an array of document ids
  */
 export const fetchNotesByDocumentIds = async (documentIds: string[]) => {
-  const response = await KibanaServices.get().http.get<{ notes: Note[]; totalCount: number }>(
-    NOTE_URL,
-    {
-      query: { documentIds },
-      version: '2023-10-31',
-    }
-  );
+  const response = await KibanaServices.get().http.get<GetNotesResponse>(NOTE_URL, {
+    query: { documentIds },
+    version: '2023-10-31',
+  });
   return response;
 };
 
@@ -79,13 +80,10 @@ export const fetchNotesByDocumentIds = async (documentIds: string[]) => {
  * Fetches all the notes for an array of saved object ids
  */
 export const fetchNotesBySaveObjectIds = async (savedObjectIds: string[]) => {
-  const response = await KibanaServices.get().http.get<{ notes: Note[]; totalCount: number }>(
-    NOTE_URL,
-    {
-      query: { savedObjectIds },
-      version: '2023-10-31',
-    }
-  );
+  const response = await KibanaServices.get().http.get<GetNotesResponse>(NOTE_URL, {
+    query: { savedObjectIds },
+    version: '2023-10-31',
+  });
   return response;
 };
 
@@ -93,7 +91,7 @@ export const fetchNotesBySaveObjectIds = async (savedObjectIds: string[]) => {
  * Deletes multiple notes
  */
 export const deleteNotes = async (noteIds: string[]) => {
-  const response = await KibanaServices.get().http.delete<{ data: unknown }>(NOTE_URL, {
+  const response = await KibanaServices.get().http.delete<DeleteNoteResponse>(NOTE_URL, {
     body: JSON.stringify({ noteIds }),
     version: '2023-10-31',
   });
diff --git a/x-pack/plugins/security_solution/public/notes/components/add_note.test.tsx b/x-pack/plugins/security_solution/public/notes/components/add_note.test.tsx
index 9b2e0596d5357..e195339c28a52 100644
--- a/x-pack/plugins/security_solution/public/notes/components/add_note.test.tsx
+++ b/x-pack/plugins/security_solution/public/notes/components/add_note.test.tsx
@@ -102,6 +102,7 @@ describe('AddNote', () => {
   });
 
   it('should render error toast if create a note fails', () => {
+    const createNoteError = new Error('This error comes from the backend');
     const store = createMockStore({
       ...mockGlobalState,
       notes: {
@@ -112,7 +113,7 @@ describe('AddNote', () => {
         },
         error: {
           ...mockGlobalState.notes.error,
-          createNote: { type: 'http', status: 500 },
+          createNote: createNoteError,
         },
       },
     });
@@ -123,9 +124,12 @@ describe('AddNote', () => {
       </TestProviders>
     );
 
-    expect(mockAddError).toHaveBeenCalledWith(null, {
-      title: CREATE_NOTE_ERROR,
-    });
+    expect(mockAddError).toHaveBeenCalledWith(
+      createNoteError,
+      expect.objectContaining({
+        title: CREATE_NOTE_ERROR,
+      })
+    );
   });
 
   it('should call onNodeAdd callback when it is available', async () => {
diff --git a/x-pack/plugins/security_solution/public/notes/components/add_note.tsx b/x-pack/plugins/security_solution/public/notes/components/add_note.tsx
index d31aaaa028b56..b3b226550b66f 100644
--- a/x-pack/plugins/security_solution/public/notes/components/add_note.tsx
+++ b/x-pack/plugins/security_solution/public/notes/components/add_note.tsx
@@ -25,6 +25,7 @@ import {
   ReqStatus,
   selectCreateNoteError,
   selectCreateNoteStatus,
+  userClosedCreateErrorToast,
 } from '../store/notes.slice';
 import { MarkdownEditor } from '../../common/components/markdown_editor';
 
@@ -101,14 +102,19 @@ export const AddNote = memo(
       setEditorValue('');
     }, [dispatch, editorValue, eventId, telemetry, timelineId, onNoteAdd]);
 
+    const resetError = useCallback(() => {
+      dispatch(userClosedCreateErrorToast());
+    }, [dispatch]);
+
     // show a toast if the create note call fails
     useEffect(() => {
       if (createStatus === ReqStatus.Failed && createError) {
-        addErrorToast(null, {
+        addErrorToast(createError, {
           title: CREATE_NOTE_ERROR,
         });
+        resetError();
       }
-    }, [addErrorToast, createError, createStatus]);
+    }, [addErrorToast, createError, createStatus, resetError]);
 
     const buttonDisabled = useMemo(
       () => disableButton || editorValue.trim().length === 0 || isMarkdownInvalid,
diff --git a/x-pack/plugins/security_solution/public/notes/store/notes.slice.test.ts b/x-pack/plugins/security_solution/public/notes/store/notes.slice.test.ts
index 1d2d197705fef..3ab0333dc1abb 100644
--- a/x-pack/plugins/security_solution/public/notes/store/notes.slice.test.ts
+++ b/x-pack/plugins/security_solution/public/notes/store/notes.slice.test.ts
@@ -46,6 +46,7 @@ import {
   fetchNotesBySavedObjectIds,
   selectNotesBySavedObjectId,
   selectSortedNotesBySavedObjectId,
+  userClosedCreateErrorToast,
 } from './notes.slice';
 import type { NotesState } from './notes.slice';
 import { mockGlobalState } from '../../common/mock';
@@ -533,6 +534,25 @@ describe('notesSlice', () => {
       });
     });
 
+    describe('userClosedCreateErrorToast', () => {
+      it('should reset create note error', () => {
+        const action = { type: userClosedCreateErrorToast.type };
+
+        expect(
+          notesReducer(
+            {
+              ...initalEmptyState,
+              error: {
+                ...initalEmptyState.error,
+                createNote: new Error(),
+              },
+            },
+            action
+          ).error.createNote
+        ).toBe(null);
+      });
+    });
+
     describe('userSelectedNotesForDeletion', () => {
       it('should set correct id when user selects a note to delete', () => {
         const action = { type: userSelectedNotesForDeletion.type, payload: '1' };
diff --git a/x-pack/plugins/security_solution/public/notes/store/notes.slice.ts b/x-pack/plugins/security_solution/public/notes/store/notes.slice.ts
index 2d24ab838ee06..979e984b5719b 100644
--- a/x-pack/plugins/security_solution/public/notes/store/notes.slice.ts
+++ b/x-pack/plugins/security_solution/public/notes/store/notes.slice.ts
@@ -103,7 +103,7 @@ export const fetchNotesByDocumentIds = createAsyncThunk<
 >('notes/fetchNotesByDocumentIds', async (args) => {
   const { documentIds } = args;
   const res = await fetchNotesByDocumentIdsApi(documentIds);
-  return normalizeEntities(res.notes);
+  return normalizeEntities('notes' in res ? res.notes : []);
 });
 
 export const fetchNotesBySavedObjectIds = createAsyncThunk<
@@ -113,7 +113,7 @@ export const fetchNotesBySavedObjectIds = createAsyncThunk<
 >('notes/fetchNotesBySavedObjectIds', async (args) => {
   const { savedObjectIds } = args;
   const res = await fetchNotesBySaveObjectIdsApi(savedObjectIds);
-  return normalizeEntities(res.notes);
+  return normalizeEntities('notes' in res ? res.notes : []);
 });
 
 export const fetchNotes = createAsyncThunk<
@@ -130,7 +130,10 @@ export const fetchNotes = createAsyncThunk<
 >('notes/fetchNotes', async (args) => {
   const { page, perPage, sortField, sortOrder, filter, search } = args;
   const res = await fetchNotesApi({ page, perPage, sortField, sortOrder, filter, search });
-  return { ...normalizeEntities(res.notes), totalCount: res.totalCount };
+  return {
+    ...normalizeEntities('notes' in res ? res.notes : []),
+    totalCount: 'totalCount' in res ? res.totalCount : 0,
+  };
 });
 
 export const createNote = createAsyncThunk<NormalizedEntity<Note>, { note: BareNote }, {}>(
@@ -199,6 +202,9 @@ const notesSlice = createSlice({
     userSelectedBulkDelete: (state) => {
       state.pendingDeleteIds = state.selectedIds;
     },
+    userClosedCreateErrorToast: (state) => {
+      state.error.createNote = null;
+    },
   },
   extraReducers(builder) {
     builder
@@ -308,12 +314,12 @@ export const selectFetchNotesError = (state: State) => state.notes.error.fetchNo
 export const selectFetchNotesStatus = (state: State) => state.notes.status.fetchNotes;
 
 export const selectNotesByDocumentId = createSelector(
-  [selectAllNotes, (state: State, documentId: string) => documentId],
+  [selectAllNotes, (_: State, documentId: string) => documentId],
   (notes, documentId) => notes.filter((note) => note.eventId === documentId)
 );
 
 export const selectNotesBySavedObjectId = createSelector(
-  [selectAllNotes, (state: State, savedObjectId: string) => savedObjectId],
+  [selectAllNotes, (_: State, savedObjectId: string) => savedObjectId],
   (notes, savedObjectId) =>
     savedObjectId.length > 0 ? notes.filter((note) => note.timelineId === savedObjectId) : []
 );
@@ -321,10 +327,10 @@ export const selectNotesBySavedObjectId = createSelector(
 export const selectDocumentNotesBySavedObjectId = createSelector(
   [
     selectAllNotes,
-    (
-      state: State,
-      { documentId, savedObjectId }: { documentId: string; savedObjectId: string }
-    ) => ({ documentId, savedObjectId }),
+    (_: State, { documentId, savedObjectId }: { documentId: string; savedObjectId: string }) => ({
+      documentId,
+      savedObjectId,
+    }),
   ],
   (notes, { documentId, savedObjectId }) =>
     notes.filter((note) => note.eventId === documentId && note.timelineId === savedObjectId)
@@ -334,7 +340,7 @@ export const selectSortedNotesByDocumentId = createSelector(
   [
     selectAllNotes,
     (
-      state: State,
+      _: State,
       {
         documentId,
         sort,
@@ -359,7 +365,7 @@ export const selectSortedNotesBySavedObjectId = createSelector(
   [
     selectAllNotes,
     (
-      state: State,
+      _: State,
       {
         savedObjectId,
         sort,
@@ -391,6 +397,7 @@ export const {
   userSearchedNotes,
   userSelectedRow,
   userClosedDeleteModal,
+  userClosedCreateErrorToast,
   userSelectedNotesForDeletion,
   userSelectedBulkDelete,
 } = notesSlice.actions;
diff --git a/x-pack/plugins/security_solution/public/timelines/containers/notes/api.ts b/x-pack/plugins/security_solution/public/timelines/containers/notes/api.ts
index 25cb18f574260..b1506c17a7cbe 100644
--- a/x-pack/plugins/security_solution/public/timelines/containers/notes/api.ts
+++ b/x-pack/plugins/security_solution/public/timelines/containers/notes/api.ts
@@ -6,7 +6,7 @@
  */
 
 import { NOTE_URL } from '../../../../common/constants';
-import type { BareNote, Note } from '../../../../common/api/timeline';
+import type { BareNote, PersistNoteRouteResponse } from '../../../../common/api/timeline';
 import { KibanaServices } from '../../../common/lib/kibana';
 
 export const persistNote = async ({
@@ -27,7 +27,7 @@ export const persistNote = async ({
   } catch (err) {
     return Promise.reject(new Error(`Failed to stringify query: ${JSON.stringify(err)}`));
   }
-  const response = await KibanaServices.get().http.patch<Note[]>(NOTE_URL, {
+  const response = await KibanaServices.get().http.patch<PersistNoteRouteResponse>(NOTE_URL, {
     method: 'PATCH',
     body: requestBody,
     version: '2023-10-31',
diff --git a/x-pack/plugins/security_solution/server/lib/timeline/routes/notes/get_notes.ts b/x-pack/plugins/security_solution/server/lib/timeline/routes/notes/get_notes.ts
index 2794fd5d8cd7d..0f3440d8ed13a 100644
--- a/x-pack/plugins/security_solution/server/lib/timeline/routes/notes/get_notes.ts
+++ b/x-pack/plugins/security_solution/server/lib/timeline/routes/notes/get_notes.ts
@@ -11,11 +11,11 @@ import type { SortOrder } from '@elastic/elasticsearch/lib/api/typesWithBodyKey'
 import { buildRouteValidationWithZod } from '@kbn/zod-helpers';
 import { timelineSavedObjectType } from '../../saved_object_mappings';
 import type { SecuritySolutionPluginRouter } from '../../../../types';
-import { NOTE_URL } from '../../../../../common/constants';
+import { MAX_UNASSOCIATED_NOTES, NOTE_URL } from '../../../../../common/constants';
 
 import { buildSiemResponse } from '../../../detection_engine/routes/utils';
 import { buildFrameworkRequest } from '../../utils/common';
-import { getAllSavedNote, MAX_UNASSOCIATED_NOTES } from '../../saved_object/notes';
+import { getAllSavedNote } from '../../saved_object/notes';
 import { noteSavedObjectType } from '../../saved_object_mappings/notes';
 import { GetNotesRequestQuery, type GetNotesResponse } from '../../../../../common/api/timeline';
 
@@ -39,6 +39,10 @@ export const getNotesRoute = (router: SecuritySolutionPluginRouter) => {
         try {
           const queryParams = request.query;
           const frameworkRequest = await buildFrameworkRequest(context, request);
+          const {
+            uiSettings: { client: uiSettingsClient },
+          } = await frameworkRequest.context.core;
+          const maxUnassociatedNotes = await uiSettingsClient.get<number>(MAX_UNASSOCIATED_NOTES);
           const documentIds = queryParams.documentIds ?? null;
           const savedObjectIds = queryParams.savedObjectIds ?? null;
           if (documentIds != null) {
@@ -48,7 +52,7 @@ export const getNotesRoute = (router: SecuritySolutionPluginRouter) => {
                 type: noteSavedObjectType,
                 search: docIdSearchString,
                 page: 1,
-                perPage: MAX_UNASSOCIATED_NOTES,
+                perPage: maxUnassociatedNotes,
               };
               const res = await getAllSavedNote(frameworkRequest, options);
               const body: GetNotesResponse = res ?? {};
@@ -58,7 +62,7 @@ export const getNotesRoute = (router: SecuritySolutionPluginRouter) => {
                 type: noteSavedObjectType,
                 search: documentIds,
                 page: 1,
-                perPage: MAX_UNASSOCIATED_NOTES,
+                perPage: maxUnassociatedNotes,
               };
               const res = await getAllSavedNote(frameworkRequest, options);
               return response.ok({ body: res ?? {} });
@@ -73,7 +77,7 @@ export const getNotesRoute = (router: SecuritySolutionPluginRouter) => {
                   id: soIdSearchString,
                 },
                 page: 1,
-                perPage: MAX_UNASSOCIATED_NOTES,
+                perPage: maxUnassociatedNotes,
               };
               const res = await getAllSavedNote(frameworkRequest, options);
               const body: GetNotesResponse = res ?? {};
@@ -85,7 +89,7 @@ export const getNotesRoute = (router: SecuritySolutionPluginRouter) => {
                   type: timelineSavedObjectType,
                   id: savedObjectIds,
                 },
-                perPage: MAX_UNASSOCIATED_NOTES,
+                perPage: maxUnassociatedNotes,
               };
               const res = await getAllSavedNote(frameworkRequest, options);
               const body: GetNotesResponse = res ?? {};
diff --git a/x-pack/plugins/security_solution/server/lib/timeline/saved_object/notes/saved_object.test.ts b/x-pack/plugins/security_solution/server/lib/timeline/saved_object/notes/saved_object.test.ts
index ed5b198932768..227c336d9a19a 100644
--- a/x-pack/plugins/security_solution/server/lib/timeline/saved_object/notes/saved_object.test.ts
+++ b/x-pack/plugins/security_solution/server/lib/timeline/saved_object/notes/saved_object.test.ts
@@ -187,6 +187,10 @@ describe('persistNote', () => {
     created_at: '2024-06-25T22:56:01.354Z',
     created_by: 'u_mGBROF_q5bmFCATbLXAcCwKa0k8JvONAwSruelyKA5E_0',
   };
+  const mockUiSettingsClientGet = jest.fn();
+  const mockUiSettingsClient = {
+    get: mockUiSettingsClientGet,
+  };
   const mockSavedObjectClient = savedObjectsClientMock.create();
   const core = coreMock.createRequestHandlerContext();
   const context = {
@@ -197,6 +201,10 @@ describe('persistNote', () => {
         ...core.savedObjects,
         client: mockSavedObjectClient,
       },
+      uiSettings: {
+        ...core.uiSettings,
+        client: mockUiSettingsClient,
+      },
     },
     resolve: jest.fn(),
   } as unknown as RequestHandlerContext;
@@ -304,7 +312,7 @@ describe('persistNote', () => {
       message: 'Cannot create more than 1000 notes without associating them to a timeline',
       note: mockNote,
     });
-
+    mockUiSettingsClientGet.mockResolvedValue(1000);
     const result = await persistNote({ request: mockRequest, noteId: null, note: mockNote });
 
     expect(result.code).toBe(403);
diff --git a/x-pack/plugins/security_solution/server/lib/timeline/saved_object/notes/saved_object.ts b/x-pack/plugins/security_solution/server/lib/timeline/saved_object/notes/saved_object.ts
index 300903f8b22ee..ff353efe0fb53 100644
--- a/x-pack/plugins/security_solution/server/lib/timeline/saved_object/notes/saved_object.ts
+++ b/x-pack/plugins/security_solution/server/lib/timeline/saved_object/notes/saved_object.ts
@@ -16,7 +16,7 @@ import { identity } from 'fp-ts/lib/function';
 import type { SavedObjectsFindOptions } from '@kbn/core/server';
 import type { AuthenticatedUser } from '@kbn/security-plugin/common';
 import { getUserDisplayName } from '@kbn/user-profile-components';
-import { UNAUTHENTICATED_USER } from '../../../../../common/constants';
+import { MAX_UNASSOCIATED_NOTES, UNAUTHENTICATED_USER } from '../../../../../common/constants';
 import type {
   Note,
   BareNote,
@@ -31,8 +31,6 @@ import { noteSavedObjectType } from '../../saved_object_mappings/notes';
 import { timelineSavedObjectType } from '../../saved_object_mappings';
 import { noteFieldsMigrator } from './field_migrator';
 
-export const MAX_UNASSOCIATED_NOTES = 1000;
-
 export const deleteNotesByTimelineId = async (request: FrameworkRequest, timelineId: string) => {
   const options: SavedObjectsFindOptions = {
     type: noteSavedObjectType,
@@ -135,7 +133,10 @@ export const createNote = async ({
   note: BareNote | BareNoteWithoutExternalRefs;
   overrideOwner?: boolean;
 }): Promise<ResponseNote> => {
-  const savedObjectsClient = (await request.context.core).savedObjects.client;
+  const {
+    savedObjects: { client: savedObjectsClient },
+    uiSettings: { client: uiSettingsClient },
+  } = await request.context.core;
   const userInfo = request.user;
 
   const noteWithCreator = overrideOwner ? pickSavedNote(noteId, { ...note }, userInfo) : note;
@@ -145,15 +146,15 @@ export const createNote = async ({
       data: noteWithCreator,
     });
   if (references.length === 1 && references[0].id === '') {
-    // Limit unassociated events to 1000
+    const maxUnassociatedNotes = await uiSettingsClient.get<number>(MAX_UNASSOCIATED_NOTES);
     const notesCount = await savedObjectsClient.find<SavedObjectNoteWithoutExternalRefs>({
       type: noteSavedObjectType,
       hasReference: { type: timelineSavedObjectType, id: '' },
     });
-    if (notesCount.total >= MAX_UNASSOCIATED_NOTES) {
+    if (notesCount.total >= maxUnassociatedNotes) {
       return {
         code: 403,
-        message: `Cannot create more than ${MAX_UNASSOCIATED_NOTES} notes without associating them to a timeline`,
+        message: `Cannot create more than ${maxUnassociatedNotes} notes without associating them to a timeline`,
         note: {
           ...note,
           noteId: uuidv1(),
diff --git a/x-pack/plugins/security_solution/server/lib/timeline/utils/common.ts b/x-pack/plugins/security_solution/server/lib/timeline/utils/common.ts
index 259719a18bdf0..a3de26000d8a0 100644
--- a/x-pack/plugins/security_solution/server/lib/timeline/utils/common.ts
+++ b/x-pack/plugins/security_solution/server/lib/timeline/utils/common.ts
@@ -23,14 +23,19 @@ export const buildFrameworkRequest = async (
   const coreContext = await context.core;
   const savedObjectsClient = coreContext.savedObjects.client;
   const user = coreContext.security.authc.getCurrentUser();
+  const uiSettings = coreContext.uiSettings;
 
   return set<FrameworkRequest>(
-    'user',
-    user,
-    set<KibanaRequest & { context: RequestHandlerContext }>(
-      'context.core.savedObjects.client',
-      savedObjectsClient,
-      request
+    'context.core.uiSettings',
+    uiSettings,
+    set<FrameworkRequest>(
+      'user',
+      user,
+      set<KibanaRequest & { context: RequestHandlerContext }>(
+        'context.core.savedObjects.client',
+        savedObjectsClient,
+        request
+      )
     )
   );
 };
diff --git a/x-pack/plugins/security_solution/server/ui_settings.ts b/x-pack/plugins/security_solution/server/ui_settings.ts
index 36b6a5a6582c8..ecf3629b54831 100644
--- a/x-pack/plugins/security_solution/server/ui_settings.ts
+++ b/x-pack/plugins/security_solution/server/ui_settings.ts
@@ -19,6 +19,7 @@ import {
   DEFAULT_INDEX_PATTERN,
   DEFAULT_INTERVAL_PAUSE,
   DEFAULT_INTERVAL_VALUE,
+  DEFAULT_MAX_UNASSOCIATED_NOTES,
   DEFAULT_RULE_REFRESH_INTERVAL_ON,
   DEFAULT_RULE_REFRESH_INTERVAL_VALUE,
   DEFAULT_RULES_TABLE_REFRESH_SETTING,
@@ -28,6 +29,7 @@ import {
   ENABLE_NEWS_FEED_SETTING,
   IP_REPUTATION_LINKS_SETTING,
   IP_REPUTATION_LINKS_SETTING_DEFAULT,
+  MAX_UNASSOCIATED_NOTES,
   NEWS_FEED_URL_SETTING,
   NEWS_FEED_URL_SETTING_DEFAULT,
   ENABLE_CCS_READ_WARNING_SETTING,
@@ -342,6 +344,26 @@ export const initUiSettings = (
       requiresPageReload: true,
       schema: schema.arrayOf(schema.string()),
     },
+    [MAX_UNASSOCIATED_NOTES]: {
+      name: i18n.translate('xpack.securitySolution.uiSettings.maxUnassociatedNotesLabel', {
+        defaultMessage: 'Maximum amount of unassociated notes',
+      }),
+      description: i18n.translate(
+        'xpack.securitySolution.uiSettings.maxUnassociatedNotesDescription',
+        {
+          defaultMessage:
+            'Defines the maximum amount of unassociated notes (notes that are not assigned to a timeline) that can be created.',
+        }
+      ),
+      type: 'number',
+      value: DEFAULT_MAX_UNASSOCIATED_NOTES,
+      schema: schema.number({
+        min: 1,
+        max: 1000,
+        defaultValue: DEFAULT_MAX_UNASSOCIATED_NOTES,
+      }),
+      requiresPageReload: false,
+    },
     [EXCLUDED_DATA_TIERS_FOR_RULE_EXECUTION]: {
       name: i18n.translate(
         'xpack.securitySolution.uiSettings.excludedDataTiersForRuleExecutionLabel',
@@ -353,8 +375,8 @@ export const initUiSettings = (
         'xpack.securitySolution.uiSettings.excludedDataTiersForRuleExecutionDescription',
         {
           defaultMessage: `
-          When configured, events from the specified data tiers are not searched during rules executions. 
-          <br/>This might help to improve rule performance or reduce execution time. 
+          When configured, events from the specified data tiers are not searched during rules executions.
+          <br/>This might help to improve rule performance or reduce execution time.
           <br/>If you specify multiple data tiers, separate values with commas. For example: data_frozen,data_cold`,
         }
       ),