diff --git a/packages/ketcher-core/src/application/indigo.ts b/packages/ketcher-core/src/application/indigo.ts
new file mode 100644
index 0000000000..95de949a50
--- /dev/null
+++ b/packages/ketcher-core/src/application/indigo.ts
@@ -0,0 +1,212 @@
+/****************************************************************************
+ * Copyright 2021 EPAM Systems
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *    http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ ***************************************************************************/
+
+import {
+  AutomapMode,
+  CalculateProps,
+  CalculateResult,
+  CheckResult,
+  CheckTypes,
+  ChemicalMimeType,
+  ConvertResult,
+  InfoResult,
+  OutputFormatType,
+  StructService
+} from 'domain/services'
+import { StructOrString } from 'application/indigo.types'
+import { KetSerializer } from 'domain/serializers'
+import { Struct } from 'domain/entities'
+
+const defaultTypes: Array<CheckTypes> = [
+  'radicals',
+  'pseudoatoms',
+  'stereo',
+  'query',
+  'overlapping_atoms',
+  'overlapping_bonds',
+  'rgroups',
+  'chiral',
+  '3d'
+]
+const defaultCalcProps: Array<CalculateProps> = [
+  'molecular-weight',
+  'most-abundant-mass',
+  'monoisotopic-mass',
+  'gross',
+  'mass-composition'
+]
+
+type ConvertOptions = {
+  outputFormat?: ChemicalMimeType
+}
+type AutomapOptions = {
+  mode?: AutomapMode
+}
+type CheckOptions = {
+  types?: Array<CheckTypes>
+}
+type CalculateOptions = {
+  properties?: Array<CalculateProps>
+}
+type RecognizeOptions = {
+  version?: string
+}
+type GenerateImageOptions = {
+  outputFormat?: OutputFormatType
+  backgroundColor?: string
+}
+
+function convertStructToString(
+  struct: StructOrString,
+  serializer: KetSerializer
+): string {
+  if (typeof struct !== 'string') {
+    const aidMap = new Map()
+    const result = struct.clone(null, null, false, aidMap)
+
+    return serializer.serialize(result)
+  }
+
+  return struct
+}
+
+export class Indigo {
+  #structService: StructService
+  #ketSerializer: KetSerializer
+
+  constructor(structService) {
+    this.#structService = structService
+    this.#ketSerializer = new KetSerializer()
+  }
+
+  info(): Promise<InfoResult> {
+    return this.#structService.info()
+  }
+
+  convert(
+    struct: StructOrString,
+    options?: ConvertOptions
+  ): Promise<ConvertResult> {
+    const outputFormat = options?.outputFormat || ChemicalMimeType.KET
+
+    return this.#structService.convert({
+      struct: convertStructToString(struct, this.#ketSerializer),
+      output_format: outputFormat
+    })
+  }
+
+  layout(struct: StructOrString): Promise<Struct> {
+    return this.#structService
+      .layout({
+        struct: convertStructToString(struct, this.#ketSerializer),
+        output_format: ChemicalMimeType.KET
+      })
+      .then((data) => this.#ketSerializer.deserialize(data.struct))
+  }
+
+  clean(struct: StructOrString): Promise<Struct> {
+    return this.#structService
+      .clean({
+        struct: convertStructToString(struct, this.#ketSerializer),
+        output_format: ChemicalMimeType.KET
+      })
+      .then((data) => this.#ketSerializer.deserialize(data.struct))
+  }
+
+  aromatize(struct: StructOrString): Promise<Struct> {
+    return this.#structService
+      .aromatize({
+        struct: convertStructToString(struct, this.#ketSerializer),
+        output_format: ChemicalMimeType.KET
+      })
+      .then((data) => this.#ketSerializer.deserialize(data.struct))
+  }
+
+  dearomatize(struct: StructOrString): Promise<Struct> {
+    return this.#structService
+      .dearomatize({
+        struct: convertStructToString(struct, this.#ketSerializer),
+        output_format: ChemicalMimeType.KET
+      })
+      .then((data) => this.#ketSerializer.deserialize(data.struct))
+  }
+
+  calculateCip(struct: StructOrString): Promise<Struct> {
+    return this.#structService
+      .calculateCip({
+        struct: convertStructToString(struct, this.#ketSerializer),
+        output_format: ChemicalMimeType.KET
+      })
+      .then((data) => this.#ketSerializer.deserialize(data.struct))
+  }
+
+  automap(struct: StructOrString, options?: AutomapOptions): Promise<Struct> {
+    const mode = options?.mode || 'discard'
+
+    return this.#structService
+      .automap({
+        struct: convertStructToString(struct, this.#ketSerializer),
+        output_format: ChemicalMimeType.KET,
+        mode
+      })
+      .then((data) => this.#ketSerializer.deserialize(data.struct))
+  }
+
+  check(struct: StructOrString, options?: CheckOptions): Promise<CheckResult> {
+    const types = options?.types || defaultTypes
+
+    return this.#structService.check({
+      struct: convertStructToString(struct, this.#ketSerializer),
+      types
+    })
+  }
+
+  calculate(
+    struct: StructOrString,
+    options?: CalculateOptions
+  ): Promise<CalculateResult> {
+    const properties = options?.properties || defaultCalcProps
+
+    return this.#structService.calculate({
+      struct: convertStructToString(struct, this.#ketSerializer),
+      properties
+    })
+  }
+
+  recognize(image: Blob, options?: RecognizeOptions): Promise<Struct> {
+    const version = options?.version || ''
+
+    return this.#structService
+      .recognize(image, version)
+      .then((data) => this.#ketSerializer.deserialize(data.struct))
+  }
+
+  generateImageAsBase64(
+    struct: StructOrString,
+    options?: GenerateImageOptions
+  ): Promise<string> {
+    const outputFormat = options?.outputFormat || 'png'
+    const backgroundColor = options?.backgroundColor || ''
+
+    return this.#structService.generateImageAsBase64(
+      convertStructToString(struct, this.#ketSerializer),
+      {
+        outputFormat,
+        backgroundColor
+      }
+    )
+  }
+}
diff --git a/packages/ketcher-core/src/application/indigo.types.ts b/packages/ketcher-core/src/application/indigo.types.ts
new file mode 100644
index 0000000000..345cc0f20a
--- /dev/null
+++ b/packages/ketcher-core/src/application/indigo.types.ts
@@ -0,0 +1,19 @@
+/****************************************************************************
+ * Copyright 2021 EPAM Systems
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *    http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ ***************************************************************************/
+
+import { Struct } from 'domain/entities'
+
+export type StructOrString = Struct | string
diff --git a/packages/ketcher-core/src/application/ketcher.ts b/packages/ketcher-core/src/application/ketcher.ts
index e6dce07737..c385237d51 100644
--- a/packages/ketcher-core/src/application/ketcher.ts
+++ b/packages/ketcher-core/src/application/ketcher.ts
@@ -16,8 +16,8 @@
 
 import {
   FormatterFactory,
-  SupportedFormat,
-  identifyStructFormat
+  identifyStructFormat,
+  SupportedFormat
 } from './formatters'
 import { GenerateImageOptions, StructService } from 'domain/services'
 
@@ -25,6 +25,7 @@ import { Editor } from './editor'
 import { MolfileFormat } from 'domain/serializers'
 import { Struct } from 'domain/entities'
 import assert from 'assert'
+import { Indigo } from 'application/indigo'
 
 function parseStruct(structStr: string, structService: StructService) {
   const format = identifyStructFormat(structStr)
@@ -47,6 +48,7 @@ export class Ketcher {
   #structService: StructService
   #formatterFactory: FormatterFactory
   #editor: Editor
+  #indigo: Indigo
 
   get editor(): Editor {
     return this.#editor
@@ -64,6 +66,11 @@ export class Ketcher {
     this.#editor = editor
     this.#structService = structService
     this.#formatterFactory = formatterFactory
+    this.#indigo = new Indigo(this.#structService)
+  }
+
+  get indigo() {
+    return this.#indigo
   }
 
   getSmiles(isExtended = false): Promise<string> {
diff --git a/packages/ketcher-core/src/domain/services/struct/structService.types.ts b/packages/ketcher-core/src/domain/services/struct/structService.types.ts
index 57b21ef5a2..fd081782c7 100644
--- a/packages/ketcher-core/src/domain/services/struct/structService.types.ts
+++ b/packages/ketcher-core/src/domain/services/struct/structService.types.ts
@@ -43,8 +43,21 @@ export interface WithSelection {
   selected?: Array<number>
 }
 
+export type CheckTypes =
+  | 'radicals'
+  | 'pseudoatoms'
+  | 'stereo'
+  | 'query'
+  | 'overlapping_atoms'
+  | 'overlapping_bonds'
+  | 'rgroups'
+  | 'chiral'
+  | '3d'
+  | 'chiral_flag'
+  | 'valence'
+
 export interface CheckData extends WithStruct {
-  types: Array<string>
+  types: Array<CheckTypes>
 }
 
 export interface CheckResult {
@@ -78,16 +91,23 @@ export interface CalculateCipData extends WithStruct, WithOutputFormat {}
 
 export interface CalculateCipResult extends WithStruct, WithFormat {}
 
+export type CalculateProps =
+  | 'molecular-weight'
+  | 'most-abundant-mass'
+  | 'monoisotopic-mass'
+  | 'gross'
+  | 'mass-composition'
+
 export interface CalculateData extends WithStruct, WithSelection {
-  properties: Array<string>
+  properties: Array<CalculateProps>
 }
 
-export interface CalculateResult {
-  [key: string]: string | number | boolean
-}
+export type CalculateResult = Record<CalculateProps, string | number | boolean>
+
+export type AutomapMode = 'discard' | 'keep' | 'alter' | 'clear'
 
 export interface AutomapData extends WithStruct, WithOutputFormat {
-  mode: string
+  mode: AutomapMode
 }
 
 export interface AutomapResult extends WithStruct, WithFormat {}
diff --git a/packages/ketcher-standalone/src/infrastructure/services/struct/indigoWorker.types.ts b/packages/ketcher-standalone/src/infrastructure/services/struct/indigoWorker.types.ts
index 586f773548..7c473d79f3 100644
--- a/packages/ketcher-standalone/src/infrastructure/services/struct/indigoWorker.types.ts
+++ b/packages/ketcher-standalone/src/infrastructure/services/struct/indigoWorker.types.ts
@@ -100,6 +100,14 @@ export interface CalculateCipCommandData
     WithStruct,
     WithFormat {}
 
+export type CalculateProps =
+  | 'molecular-weight'
+  | 'most-abundant-mass'
+  | 'monoisotopic-mass'
+  | 'gross'
+  | 'gross-formula'
+  | 'mass-composition'
+
 export interface CalculateCommandData
   extends CommandData,
     WithStruct,
diff --git a/packages/ketcher-standalone/src/infrastructure/services/struct/standaloneStructService.ts b/packages/ketcher-standalone/src/infrastructure/services/struct/standaloneStructService.ts
index 304e597378..2a3fdf9e4f 100644
--- a/packages/ketcher-standalone/src/infrastructure/services/struct/standaloneStructService.ts
+++ b/packages/ketcher-standalone/src/infrastructure/services/struct/standaloneStructService.ts
@@ -19,6 +19,7 @@ import {
   AutomapCommandData,
   CalculateCipCommandData,
   CalculateCommandData,
+  CalculateProps,
   CheckCommandData,
   CleanCommandData,
   Command,
@@ -116,8 +117,8 @@ function convertMimeTypeToOutputFormat(
   return format
 }
 
-function mapCalculatedPropertyName(property: string) {
-  let mappedProperty: string | undefined
+function mapCalculatedPropertyName(property: CalculateProps) {
+  let mappedProperty: CalculateProps | undefined
   switch (property) {
     case 'gross-formula': {
       mappedProperty = 'gross'
@@ -544,18 +545,20 @@ class IndigoService implements StructService {
         worker.terminate()
         const msg: OutputMessage<string> = e.data
         if (!msg.hasError) {
-          const calculatedProperties = JSON.parse(msg.payload!) as KeyValuePair
+          const calculatedProperties: CalculateResult = JSON.parse(msg.payload!)
           const result: CalculateResult = Object.entries(
             calculatedProperties
           ).reduce((acc, curr) => {
             const [key, value] = curr
-            const mappedPropertyName = mapCalculatedPropertyName(key)
+            const mappedPropertyName = mapCalculatedPropertyName(
+              key as CalculateProps
+            )
             if (properties.includes(mappedPropertyName)) {
               acc[mappedPropertyName] = value
             }
 
             return acc
-          }, {})
+          }, {} as CalculateResult)
           resolve(result)
         } else {
           reject(msg.error)