diff --git a/packages/react-debug-tools/src/ReactDebugHooks.js b/packages/react-debug-tools/src/ReactDebugHooks.js
index a09da97f90d72..6409647772eff 100644
--- a/packages/react-debug-tools/src/ReactDebugHooks.js
+++ b/packages/react-debug-tools/src/ReactDebugHooks.js
@@ -367,7 +367,11 @@ const DispatcherProxyHandler = {
   },
 };
 
-const DispatcherProxy = new Proxy(Dispatcher, DispatcherProxyHandler);
+// `Proxy` may not exist on some platforms
+const DispatcherProxy =
+  typeof Proxy === 'undefined'
+    ? Dispatcher
+    : new Proxy(Dispatcher, DispatcherProxyHandler);
 
 // Inspect