diff --git a/packages/react-dom/npm/profiling.js b/packages/react-dom/npm/profiling.js
new file mode 100644
index 0000000000000..91f89f07ffe13
--- /dev/null
+++ b/packages/react-dom/npm/profiling.js
@@ -0,0 +1,38 @@
+'use strict';
+
+function checkDCE() {
+  /* global __REACT_DEVTOOLS_GLOBAL_HOOK__ */
+  if (
+    typeof __REACT_DEVTOOLS_GLOBAL_HOOK__ === 'undefined' ||
+    typeof __REACT_DEVTOOLS_GLOBAL_HOOK__.checkDCE !== 'function'
+  ) {
+    return;
+  }
+  if (process.env.NODE_ENV !== 'production') {
+    // This branch is unreachable because this function is only called
+    // in production, but the condition is true only in development.
+    // Therefore if the branch is still here, dead code elimination wasn't
+    // properly applied.
+    // Don't change the message. React DevTools relies on it. Also make sure
+    // this message doesn't occur elsewhere in this function, or it will cause
+    // a false positive.
+    throw new Error('^_^');
+  }
+  try {
+    // Verify that the code above has been dead code eliminated (DCE'd).
+    __REACT_DEVTOOLS_GLOBAL_HOOK__.checkDCE(checkDCE);
+  } catch (err) {
+    // DevTools shouldn't crash React, no matter what.
+    // We should still report in case we break this code.
+    console.error(err);
+  }
+}
+
+if (process.env.NODE_ENV === 'production') {
+  // DCE check should happen before ReactDOM bundle executes so that
+  // DevTools can report bad minification during injection.
+  checkDCE();
+  module.exports = require('./cjs/react-dom.profiling.min.js');
+} else {
+  module.exports = require('./cjs/react-dom.development.js');
+}
diff --git a/packages/react-dom/package.json b/packages/react-dom/package.json
index 31f29f85ad9c1..4b5186d1486b6 100644
--- a/packages/react-dom/package.json
+++ b/packages/react-dom/package.json
@@ -25,6 +25,7 @@
     "LICENSE",
     "README.md",
     "index.js",
+    "profiling.js",
     "server.js",
     "server.browser.js",
     "server.node.js",